CAS 87-08-1

Penicilina V

Descrição:

Penicilina V, também conhecido como fenoximetilpenicilina, é um antibiótico de espectro estreito que pertence à classe das penicilinas. É utilizado principalmente para tratar infecções bacterianas, particularmente aquelas causadas por organismos gram-positivos. A fórmula química de Penicilina V é C16H17N2O5S, e apresenta um anel beta-lactâmico, que é essencial para sua atividade antibacteriana. Este composto é caracterizado por sua estabilidade em ambientes ácidos, tornando-o adequado para administração oral, ao contrário de algumas outras penicilinas que são mais sensíveis ao ácido estomacal. Penicilina V é tipicamente administrado na forma de seu sal potássico, melhorando sua solubilidade e biodisponibilidade. Seu mecanismo de ação envolve a inibição da síntese da parede celular bacteriana, levando à lise celular e morte. Efeitos colaterais comuns podem incluir reações alérgicas, distúrbios gastrointestinais e, em casos raros, superinfecção devido à interrupção da flora normal. Penicilina V é frequentemente prescrito para condições como faringite estreptocócica, infecções de pele e infecções dentárias, demonstrando sua importância clínica no tratamento de várias infecções bacterianas.

Fórmula: C₁₆H₁₈N₂O₅S

InChI: InChI=1S/C16H18N2O5S/c1-16(2)12(15(21)22)18-13(20)11(14(18)24-16)17-10(19)8-23-9-6-4-3-5-7-9/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22)/t11-,12+,14-/m1/s1

Chave InChI: InChIKey=BPLBGHOLXOTWMN-MBNYWOFBSA-N

SMILES: C(O)(=O)[C@@H]1N2[C@@]([C@H](NC(COC3=CC=CC=C3)=O)C2=O)(SC1(C)C)[H]

Sinónimos:

• (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[(2-phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-(2-phenoxyacetamido)-
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(2-phenoxyacetyl)amino]-, (2S,5R,6R)-
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(phenoxyacetyl)amino]-, [2S-(2α,5α,6β)]-
• 6-(Phenoxyacetamido)penicillanic acid
• Acipen-V
• Calcipen
• Crystapen V
• Distaquaine V
• Eskacillin V
• Fenacilin
• Fenoximetilpenicilina
• Meropenin
• Oracillin
• Oracilline
• Oratren
• Orocillin
• Ospen
• Pen-Oral
• Pen-Vee
• Pen-vee-oral
• Penicillin V
• Penicillin V (Phenoxymethylpenicillinic Acid)
• Penicillin, phenoxymethyl-
• Phenocillin
• Phenopenicillin
• Phenospen
• Phenoxymethylpenicillin
• Phenoxymethylpenicilline
• Phenoxymethylpenicillinic acid
• Stabicillin
• V-Cil
• V-Cillin
• V-Cylina
• V-Cyline
• V-Tablopen
• Vebecillin
• [2S-(2α,5α,6β)]-3,3-dimethyl-7-oxo-6-[(phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

PHENOXYMETHYLPENICILLIN FOR SYSTEM SUITABILITY CRS

CAS: 87-08-1

PHENOXYMETHYLPENICILLIN FOR SYSTEM SUITABILITY CRS

Fórmula: C₁₆H₁₈N₂O₅S

Cor e Forma: Crystalline Powder. White. Powder.

Peso molecular: 350.3895

Ref: 41-Y0001868

PHENOXYMETHYLPENICILLIN RS

CAS: 87-08-1

PHENOXYMETHYLPENICILLIN RS

Fórmula: C₁₆H₁₈N₂O₅S

Peso molecular: 350.3895

Ref: 41-ICRS0383

PHENOXYMETHYLPENICILLIN CRS

CAS: 87-08-1

PHENOXYMETHYLPENICILLIN CRS

Fórmula: C₁₆H₁₈N₂O₅S

Cor e Forma: Crystalline Powder. White. Powder.

Peso molecular: 350.3895

Ref: 41-P1000000

Penicillin V

CAS: 87-08-1

Penicillins and their derivatives with a penicillanic a

Fórmula: C₁₆H₁₈N₂O₅S

Cor e Forma: Powder

Peso molecular: 350.38 g/mol

Ref: 45-1504489

(2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[(2-phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

CAS: 87-08-1

Fórmula: C₁₆H₁₈N₂O₅S

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 350.3895

Ref: IN-DA00GROE

Penicillin V

CAS: 87-08-1

Penicillin V: orally active antibiotic against Streptococci, C. difficile, and S. aureus; treats otitis, sinusitis, pharyngitis, tonsillitis.

Fórmula: C₁₆H₁₈N₂O₅S

Cor e Forma: Solid

Peso molecular: 350.39

Ref: TM-T73601

Phenoxymethylpenicillin

CAS: 87-08-1

Fórmula: C₁₆H₁₈N₂O₅S

Cor e Forma: Neat

Peso molecular: 350.39

Ref: 04-C16045500

Phenoxymethylpenicillin 100 µg/mL in Acetonitrile

CAS: 87-08-1

Fórmula: C₁₆H₁₈N₂O₅S

Cor e Forma: Single Solution

Peso molecular: 350.39

Ref: 04-A16045500AL-100

Penicillin V

Produto Controlado

CAS: 87-08-1

Applications Penicillin V is an antibacterial agent. This compound is a contaminant of emerging concern (CECs).
References Goldenthal, E.I., et al.: Toxicol. Appl. Pharmacol., 18, 185 (1971), Dunham, J.M., et al.: Anal. Profiles Drug Subs., 1, 249 (1972),

Fórmula: C₁₆H₁₈N₂O₅S

Cor e Forma: White To Off-White

Peso molecular: 350.39

Ref: TR-P223505

Penicillin V

CAS: 87-08-1

Penicillin V is an antibiotic that belongs to the class of penicillins. It is used in the treatment of bacterial infections, such as streptococcal pharyngitis and infectious diseases. Penicillin V binds to the penicillin-binding proteins, which are located on the outer surface of the bacterial membrane and prevent cell wall synthesis. This binding inhibits cell wall biosynthesis by preventing transpeptidation and transglycosylation reactions and leads to cell death. Penicillin V also inhibits the production of certain cytokines, including interleukin-1β (IL-1β) and tumor necrosis factor α (TNFα), which may be a result of its ability to inhibit Toll-like receptor 4 (TLR4). The solubility data for penicillin V was obtained from experiments conducted with experimental animals. The oral cephalosporins were shown to have a greater affinity for penicillin-binding proteins than pen

Fórmula: C₁₆H₁₈N₂O₅S

Pureza: Min. 95%

Peso molecular: 350.39 g/mol

Ref: 3D-AAA08708