CAS: 879085-55-9 - 2-chloro-N-[4-chloro-3-(pyridin-2-yl)phenyl]-4-(methylsulfonyl)benzamide

Fórmula: C₁₉H₁₄Cl₂N₂O₃S

InChI: InChI=1S/C19H14Cl2N2O3S/c1-27(25,26)13-6-7-14(17(21)11-13)19(24)23-12-5-8-16(20)15(10-12)18-4-2-3-9-22-18/h2-11H,1H3,(H,23,24)

Chave InChI: InChIKey=BPQMGSKTAYIVFO-UHFFFAOYSA-N

SMILES: O=C(NC=1C=CC(Cl)=C(C1)C2=NC=CC=C2)C3=CC=C(C=C3Cl)S(=O)(=O)C

Sinónimos:

• 2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide
• Benzamide, 2-Chloro-N-[4-Chloro-3-(2-Pyridinyl)Phenyl]-4-(Methylsulfonyl)-
• Erivedge
• Gdc-0449
• Vismodegib
• Vismodegib (GDC-0449)

Vismodegib

CAS: 879085-55-9

• Fórmula: C₁₉H₁₄Cl₂N₂O₃S
• Cor e Forma: White To Off-White Solid
• Peso molecular: 421.31

Vismodegib-d4

CAS: 1450990-33-6 879085-55-9

• Fórmula: C₁₉H₁₀D₄Cl₂N₂O₃S
• Cor e Forma: White To Off-White Solid
• Peso molecular: 425.32

Vismodegib

CAS: 879085-55-9

Vismodegib (GDC-0449) is a hedgehog pathway inhibitor (IC50: 3 nM). It also inhibits P-gp (IC50: …

• Fórmula: C₁₉H₁₄Cl₂N₂O₃S
• Pureza: 98% - 99.99%
• Cor e Forma: Solid
• Peso molecular: 421.3

Vismodegib

CAS: 879085-55-9

• Fórmula: C₁₉H₁₄Cl₂N₂O₃S
• Pureza: 99.41% (Typical Value in Batch COA)
• Cor e Forma: off-white solid
• Peso molecular: 421.30g/mol

Vismodegib

CAS: 879085-55-9

Applications Vismodegib targets the Hedgehog (Hh) pathway. Inhibition of the Hh signaling may be effective …

• Fórmula: C₁₉H₁₄Cl₂N₂O₃S
• Cor e Forma: Off-White
• Peso molecular: 421.30

Vismodegib

CAS: 879085-55-9

Vismodegib is a Hedgehog (Hh) pathway inhibitor belonging to the 2-arylpyridine class. It acts as …

• Fórmula: C₁₉H₁₄Cl₂N₂O₃S
• Pureza: Min. 95%
• Cor e Forma: Powder
• Peso molecular: 421.30 g/mol

Vismodegib-d7

CAS: 879085-55-9

• Fórmula: C₁₉D₇H₇Cl₂N₂O₃S
• Cor e Forma: Neat
• Peso molecular: 428.34