CAS 88889-14-9

Fosinopril sódico

Descrição:

Fosinopril sódico é um inibidor da enzima conversora de angiotensina (ECA) usado principalmente no tratamento da hipertensão e insuficiência cardíaca. É um pró-fármaco que é convertido no corpo em sua forma ativa, fosinoprilato, que inibe a enzima ECA, levando a uma diminuição na produção de angiotensina II, um potente vasoconstritor. Isso resulta em vasodilatação, redução da pressão arterial e diminuição da carga de trabalho do coração. Fosinopril sódico é caracterizado por sua estrutura única, que inclui um grupo ácido fosfínico, contribuindo para seu mecanismo de ação. É tipicamente administrado por via oral e tem uma meia-vida relativamente longa, permitindo a dosagem uma vez ao dia. Efeitos colaterais comuns podem incluir tontura, tosse e níveis elevados de potássio. Assim como outros inibidores da ECA, é contraindicado na gravidez e deve ser usado com cautela em pacientes com comprometimento renal. No geral, Fosinopril sódico é um medicamento eficaz para o manejo de condições cardiovasculares, com um perfil de segurança bem estabelecido quando usado adequadamente.

Fórmula: C₃₀H₄₆NNaO₇P

InChI: InChI=1/C30H46NO7P.Na/c1-4-28(33)37-30(22(2)3)38-39(36,18-12-11-15-23-13-7-5-8-14-23)21-27(32)31-20-25(19-26(31)29(34)35)24-16-9-6-10-17-24;/h5,7-8,13-14,22,24-26,30H,4,6,9-12,15-21H2,1-3H3,(H,34,35);/q;+1/p-1/t25-,26+,30+,39-;/m1./s1

Chave InChI: InChIKey=NIDZYXQFQSHBTG-WATAJHSMSA-N

SMILES: C(CP(O[C@H](OC(CC)=O)[C@@H](C)C)(CCCCC1=CC=CC=C1)=O)(=O)N2C[C@@H](C[C@H]2C(O)=O)[C@H]3CCCCC3.[Na]

Sinónimos:

• (4S)-4-Cyclohexyl-1-{[(RS)-2-methyl-1-(propionyloxy)propoxy]-(4-phenylbutyl)phosphinylacetyl}-L-proline sodium salt
• (4S)-4-cyclohexyl-1-{[(R)-[2-methyl-1-(propanoyloxy)propoxy](4-phenylbutyl)phosphoryl]acetyl}-L-proline
• (4S)-4-cyclohexyl-1-{[{[(1S)-2-methyl-1-(propanoyloxy)propyl]oxy}(4-phenylbutyl)phosphoryl]acetyl}-L-proline
• <span class="text-smallcaps">L</span>-Proline, 4-cyclohexyl-1-[2-[(R)-[(1S)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-, sodium salt (1:1), (4S)-
• <span class="text-smallcaps">L</span>-Proline, 4-cyclohexyl-1-[[(R)-[(1S)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-, sodium salt, (4S)-
• <span class="text-smallcaps">L</span>-Proline, 4-cyclohexyl-1-[[[2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-, sodium salt, [1[S*(R*)],2α,4β]-
• Acecor
• Eosinopril
• Fosenopril sodium
• Monopril
• Secorvas
• Sq 28555
• Staril
• sodium (2S,4S)-4-cyclohexyl-1-({[2-methyl-1-(propanoyloxy)propoxy](4-phenylbutyl)phosphoryl}acetyl)pyrrolidine-2-carboxylate
• sodium (2S,4S)-4-cyclohexyl-1-{[(R)-{[(1S)-2-methyl-1-(propanoyloxy)propyl]oxy}(4-phenylbutyl)phosphoryl]acetyl}pyrrolidine-2-carboxylate
• L-Proline, 4-cyclohexyl-1-[2-[(R)-[(1S)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-, sodium salt (1:1), (4S)-
• L-Proline, 4-cyclohexyl-1-[[(R)-[(1S)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-, sodium salt, (4S)-
• Fosinopril sodium
• L-Proline, 4-cyclohexyl-1-[[[2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-, sodium salt, [1[S*(R*)],2α,4β]-
• ELIDIUR
• (4S)-4-CYCLOHEXYL-1-[[(R)-[(1S)-2-METHYL-1-(1-OXOPROPOXY)PROPOXY](4-PHENYLBUTYL)PHOSPHINYL]ACETYL]-L-PROLINE
• 4β-Cyclohexyl-1-[[[(S)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-L-proline sodium salt
• FOSINOPRIL-D5 SODIUM SALT
• FOSINOPRIL SODIUM SALT
• FOSINORM
• Forsinopril sodium salt
• FOSINOPRIL NA
• Dynacil, Elidiur, Fosinorm, Monopril, Staril, Tensozide, (4S)-4-Cyclohexyl-1-[[(R)-[(1S)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-L-proline
• TENSOZIDE
• FOSINPRIL SODIUM

FOSINOPRIL SODIUM CRS

CAS: 88889-14-9

FOSINOPRIL SODIUM CRS

Fórmula: C₃₀H₄₆NO₇P

Cor e Forma: Powder

Peso molecular: 563.6625

Ref: 41-Y0001227

Fosinopril sodium

CAS: 88889-14-9

Fosinopril sodium

Fórmula: C₃₀H₄₅NNaO₇P

Pureza: 99.5%

Cor e Forma: Off-White

Peso molecular: 585.28313

Ref: 47-1091

Fosinopril Sodium

CAS: 88889-14-9

Cardiovascular drugs, not elsewhere specified or includ

Fórmula: C₃₀H₄₅NO₇PNa

Cor e Forma: Powder

Peso molecular: 585.28313

Ref: 45-1283404

L-Proline,4-cyclohexyl-1-[[(R)-[(1S)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-, sodium salt, (4S)-

CAS: 88889-14-9

Fórmula: C₃₀H₄₅NNaO₇P

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 585.6443

Ref: IN-DA00IFIB

Fosinopril sodium

CAS: 88889-14-9

Fosinopril sodium: ACE inhibitor prodrug for hypertension, becomes active metabolite fosinoprilat.

Fórmula: C₃₀H₄₅NO₇P·Na

Pureza: 99.37% - 99.40%

Cor e Forma: White To Off-White Crystalline Solid

Peso molecular: 585.65

Ref: TM-T1489

Fosinopril Sodium Salt

CAS: 88889-14-9

Fórmula: C₃₀H₄₅NO₇P·Na

Cor e Forma: White To Off-White Solid

Peso molecular: 585.66

Ref: 4Z-F-121

Fosinopril Sodium

CAS: 88889-14-9

Fosinopril Sodium

Pureza: 98%

Peso molecular: 586.64g/mol

Ref: 54-OR1029490

Fosinopril sodium

CAS: 88889-14-9

Fosinopril sodium

Pureza: ≥98%

Peso molecular: 585.65g/mol

Ref: 54-BUP11288

Fosinopril sodium salt

CAS: 88889-14-9

Fórmula: C₃₀H₄₅NO₇P·Na

Peso molecular: 585.64

Ref: 7W-GP0614

Fosinopril-d5 Sodium Salt

CAS: 88889-14-9

Fórmula: C₃₀H₄₀D₅NO₇P·Na

Cor e Forma: White To Off-White Solid

Peso molecular: 567.70 22.99

Ref: 4Z-F-1218

Fosinopril Sodium

CAS: 88889-14-9

Fórmula: C₃₀H₄₅NNaO₇P

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 585.65

Ref: 3B-F1242

Fosinopril Sodium

CAS: 88889-14-9

Cor e Forma: Neat

Ref: 86-MM0645.00

Fosinopril Sodium Salt

CAS: 88889-14-9

Applications A phosphinic acid containing angiotensin converting enzyme (ACE) inhibitor. Antihypertensive.
References Singhvi, S.M., et al.: Br. J. Clin. Pharmacol., 25, 9 (1988), Sullivan, P.A., et al.: Am. J. Hypertension, 1, 280S (1988),

Fórmula: C₃₀H₄₅NO₇P·Na

Cor e Forma: Neat

Peso molecular: 585.64

Ref: TR-F727800

Fosinopril sodium

CAS: 88889-14-9

Angiotensin converting enzyme inhibitor

Fórmula: C₃₀H₄₅NNaO₇P

Pureza: Min. 98 Area-%

Cor e Forma: White Off-White Powder

Peso molecular: 585.64 g/mol

Ref: 3D-FF23598

Fosinopril sodium salt - Bio-X ™

CAS: 88889-14-9

Fosinopril belongs to the angiotensin-converting enzyme (ACE) inhibitor class of drugs, which prevents the conversion of angiotensin I to angiotensin II. This leads to decreases in blood pressure and slows down the progression of kidney disease, hypertension and heart failure.

Fórmula: C₃₀H₄₆NO₇P•Na

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 586.65 g/mol

Ref: 3D-BF164489