CAS 9007-43-6

Citocromo c

Descrição:

Citocromo c é uma pequena proteína heme encontrada nas mitocôndrias de células eucarióticas, desempenhando um papel crucial na cadeia de transporte de elétrons, que é essencial para a respiração celular. É caracterizada por sua capacidade de sofrer oxidação e redução reversíveis, facilitando a transferência de elétrons entre os complexos III e IV da cadeia respiratória mitocondrial. A proteína contém um grupo heme, que é responsável por sua atividade redox e lhe confere uma cor distintiva. Citocromo c é altamente conservada entre espécies, indicando sua importância biológica fundamental. Geralmente, existe como uma proteína solúvel no espaço intermembranar das mitocôndrias e está envolvida na apoptose, onde pode ser liberada no citosol para ativar caspases. A estrutura molecular de Citocromo c inclui uma forma globular compacta, com um peso molecular que varia ligeiramente entre diferentes organismos. Sua estabilidade e função podem ser influenciadas por fatores como pH, temperatura e a presença de ligantes. No geral, Citocromo c é vital para a produção de energia e regulação celular em organismos aeróbicos.

Fórmula: Unspecified

InChI: InChI=1/C42H54N8O6S2.Fe/c1-19-25(9-11-37(51)52)33-16-34-26(10-12-38(53)54)20(2)30(48-34)14-35-40(24(6)58-18-28(44)42(56)46-8)22(4)32(50-35)15-36-39(21(3)31(49-36)13-29(19)47-33)23(5)57-17-27(43)41(55)45-7;/h13-16,23-24,27-28H,9-12,17-18,43-44H2,1-8H3,(H6,45,46,47,48,49,50,51,52,53,54,55,56);/q;+2/p-2/b29-13-,30-14-,31-13-,32-15-,33-16-,34-16-,35-14-,36-15-;

SMILES: Cc1c(CCC(=O)O)c2=CC3=NC(=CC4=NC(=Cc5c(c(C)c(C=c1[nH]2)[nH]5)C(C)SCC(C(=O)[N-]C)[NH3+])C(=C4C(C)SCC(C(=NC)O)N)C)C(=C3CCC(=O)O)C.[Fe]

Sinónimos:

• Citocromo C
• Cromoci
• Cytochrom c
• Cytochrome (bovine heart)
• Cytochrome C (horse heart)
• Cytochrome CymA
• Cytochrome c from horse heart
• Cytochrome c, Equine Heart
• Cytochrome�c equine heart
• Cytochrome�c from pigeon breast muscle
• Cytomac P
• Cytorest
• Ferricytochrome c
• Ferrocytochrome c
• Landrax
• Microperoxidase
• cytochrome C from bison heart
• cytochrome C from bovine heart
• cytochrome C from chicken heart
• cytochrome C from dog heart
• cytochrome C from pigeon breast muscle
• cytochrome C from porcine heart
• cytochrome C from rabbit heart
• cytochrome C from rat heart
• cytochrome C from saccharomyces*cerevisiae
• cytochrome C from sheep heart
• cytochrome C from tuna heart
• cytochrome C peptide map control
• cytochrome C practical grade: from*bovine heart
• iron(2+) (1Z,6Z,12Z,17Z)-4,9-bis(1-{[2-amino-3-(methylamino)-3-oxopropyl]sulfanyl}ethyl)-15,19-bis(2-carboxyethyl)-5,10,14,20-tetramethyl-21,22,23,24-tetraazapentacyclo[16.2.1.1~3,6~.1~8,11~.1~13,16~]tetracosa-1,3(24),4,6,8,10,12,14,16(22),17,19-undecaene-21,23-diide (non-preferred name)
• CYTOCHROME-C

Cytochrome C

CAS: 9007-43-6

Cytochrome C

Peso molecular: 884.89g/mol

Ref: 54-BUP20270

Cytochrome C, from equine heart

CAS: 9007-43-6

Pureza: ≥ 90.0%

Cor e Forma: Red to dark red or brown powder

Peso molecular: -

Ref: 7W-GE9437

Cytochrome C

CAS: 9007-43-6

Cytochrome C, class 1 c-type protein, has varied functions based on location and conditions.

Fórmula: C₄₂H₅₂FeN₈O₆S₂

Pureza: 95%

Cor e Forma: Brown-Red Crystalline Powder

Peso molecular: 884.9

Ref: TM-T9782

Cytochrome C

CAS: 9007-43-6

Fórmula: C₄₂H₅₂FeN₈O₆S₂

Cor e Forma: Neat

Peso molecular: 884.89

Ref: TR-C272015

Cytochrome C

CAS: 9007-43-6

Cytochrome C is a heme protein, which is predominantly found in the mitochondria of eukaryotic cells. Its source is the electron transport chain, where it functions as an essential component in the process of oxidative phosphorylation. Cytochrome C facilitates the transfer of electrons between Complex III and Complex IV, a crucial step in cellular respiration.In addition to its role in energy production, Cytochrome C is involved in the intrinsic pathway of apoptosis. Upon release into the cytosol, it binds to Apaf-1, leading to the formation of the apoptosome and subsequent activation of caspases that drive the apoptotic cascade. This dual functionality makes Cytochrome C a critical molecule in both energy metabolism and programmed cell death.Researchers utilize Cytochrome C in various applications, including the study of electron transport mechanisms, assays to measure apoptosis, and investigations into mitochondrial disorders. Its role as an apoptotic marker also aids in cancer research, providing insights into cell death regulation.Molecular weight is approx 12,000Da.

Fórmula: C₄₂H₅₄FeN₈O₆S₂

Pureza: (%) Min. 95%

Cor e Forma: Red Powder

Peso molecular: 12,000 g/mol

Ref: 3D-FC32167

Cytochrome C (Oxidized) (Type 1) ex. Horse Heart extrapure, 90%

CAS: 9007-43-6

Pureza: ~ 90%

Cor e Forma: Brown to Very Dark Brown and Red to Very Dark Red, crystalline powder

Ref: SR-81551

Cytochrome C (Oxidized) (Type 2) ex. Horse Heart, 95%

CAS: 9007-43-6

Pureza: min. 95% of reduced Cyto.C

Cor e Forma: Red to brownish red, Crystalline powder

Ref: SR-90777

Cytochrome c

CAS: 9007-43-6

Pureza: BioReagent, ≥95%(SDS-PAGE)

Cor e Forma: Solid

Peso molecular: 884.28

Ref: 10-F996428

Cytochrome C

CAS: 9007-43-6

Fórmula: C₄₂H₅₂FeN₈O₆S₂

Pureza: 99%

Cor e Forma: Solid

Peso molecular: 884.8872800000004

Ref: IN-DA00GRJG