CAS 9011-18-1

Sulfato de dextrano sódico

Descrição:

Sulfato de dextrano sódico é um polissacarídeo sulfato derivado do dextrano, um glucano ramificado complexo. É caracterizado por seu alto peso molecular e é tipicamente usado como anticoagulante e em várias aplicações biomédicas. A substância aparece como um pó branco a off-white e é solúvel em água, formando uma solução viscosa. Sulfato de dextrano sódico exibe uma carga negativa devido aos grupos sulfato, o que contribui para sua capacidade de interagir com proteínas e outras biomoléculas, tornando-o útil em sistemas de liberação de medicamentos e como agente estabilizante em várias formulações. Além disso, tem sido estudado por seus potenciais efeitos terapêuticos, incluindo propriedades antivirais e anti-inflamatórias. Seu perfil de segurança é geralmente favorável, mas pode causar reações adversas em alguns indivíduos, particularmente em altas concentrações. Assim como com qualquer substância química, diretrizes adequadas de manuseio e uso devem ser seguidas para garantir segurança e eficácia em suas aplicações.

Fórmula: H₂O₄S·xNa·xUnspecified

Sinónimos:

• Asuro
• Colyonal
• Dexnon
• Dextralip 15
• Dextran Sulfate Sodium
• Dextran sodium sulfate
• Dextran sulfate sodium salt
• Dextran sulfuric acid ester sodium salt
• Dextran, hydrogen sulfate, sodium salt
• Dextransulfate sodium sulfur
• Dextrarine
• Dexulate
• MDS (polysaccharide)
• MDS-Kowa A

Dextran sulfate sodium salt - MW 40,000

CAS: 9011-18-1

Dextran sulphate is a dextran derivative whose ulcer (colitis) -causing properties were first reported in hamsters and extrapolated a few years later to mice and rats. The exact mechanisms through which dextran sulphate induces intestinal inflammation are unclear but may be the result of direct damage of the monolayer of epithelial cells in the colon, leading to the crossing of intestinal contents (e.g., commensal bacteria and their products) into underlying tissue and therefore induction of inflammation.  The dextran sulphate sodium induced ulceration model in laboratory animals has some advantages when compared to other animal models of colitis, due to its simplicity and has many similarities to human inflammatory bowel disease.

Cor e Forma: Off-White Powder

Ref: 3D-YD31804

Dextran sulfate sodium salt - MW 9,000-16,000

CAS: 9011-18-1

Dextran sulphate is a dextran derivative whose ulcer (colitis) -causing properties were first reported in hamsters and extrapolated a few years later to mice and rats. The exact mechanisms through which dextran sulphate induces intestinal inflammation are unclear but may be the result of direct damage of the monolayer of epithelial cells in the colon, leading to the crossing of intestinal contents (for e.g. commensal bacteria and their products) into underlying tissue and therefore induction of inflammation.  The dextran sulphate sodium induced ulceration model in laboratory animals has some advantages, when compared to other animal models of colitis, due to its simplicity and similarities to human inflammatory bowel disease.

Cor e Forma: Powder

Ref: 3D-YD31802

Dextran sulfate sodium salt (MW 5000)

CAS: 9011-18-1

Pureza: 98%

Ref: 10-F554564

Dextran sulfate sodium - MW 5,000-8,000

CAS: 9011-18-1

Dextran sulphate is a dextran derivative whose ulcer (colitis) -causing properties were first reported in hamsters and extrapolated a few years later to mice and rats. The exact mechanisms through which dextran sulphate induces intestinal inflammation are unclear but may be the result of direct damage of the monolayer of epithelial cells in the colon, leading to the crossing of intestinal contents (for e.g. commensal bacteria and their products) into underlying tissue and therefore induction of inflammation.  The dextran sulphate sodium induced ulceration model in laboratory animals has some advantages, when compared to other animal models of colitis, due to its simplicity and similarities to human inflammatory bowel disease.

Fórmula: (C₆H₇Na₃O₁₄S₃)n

Pureza: Min. 95%

Cor e Forma: Powder

Ref: 3D-YD31801

Dextran Sulphate Sodium Salt 30-50(DSS 35-50) ex. Leuconostoc Sp.Colitis Grade for molecular biology

CAS: 9011-18-1

Cor e Forma: White to off-white, Powder, Clear, Colourless to pale yellow

Peso molecular: made from Dextran 35 - 50 KDa

Ref: SR-76203

Dextran Sulphate Sodium Salt 500 (DSS 500) ex. Leuconostoc Sp. for molecular biology

CAS: 9011-18-1

Cor e Forma: White to pale yellow, Powder, Clear

Peso molecular: made from Dextran 500 KDa

Ref: SR-99629

Dextran sulfate sodium salt - MW 150,000

CAS: 9011-18-1

Induces ulceration; used to model inflammatory bowel disease

Pureza: Min. 95%

Cor e Forma: Powder

Ref: 3D-OD157161

Dextran sulfate sodium - MW 3000-6000

CAS: 9011-18-1

Dextran sulfate sodium is a complex carbohydrate that consists of a linear chain of many glucose molecules. It is often used as a gel to protect the bowel during radiation therapy and in the treatment of severe burns. Dextran sulfate sodium can be modified with methylation, click modification, fluorination, saccharide, or glycosylation. Dextran sulfate sodium also has many applications in biochemistry and medicine such as being used as an osmotic agent in cell culture media, after being glycosylated it can be used to treat inflammatory bowel disease. This product is custom synthesized by our company and is available in various sizes from MW 3000-6000.

Pureza: Min. 95%

Cor e Forma: Powder

Ref: 3D-YD176024

Dextran sulfate sodium salt - MW 9,000-16,000

CAS: 9011-18-1

Dextran sulfate sodium salt is a water-soluble polymer that is used as a drug carrier and has many applications in the pharmaceutical industry. It is an oligosaccharide with an average molecular weight of 9,000 to 16,000 Daltons. Dextran sulfate sodium salt can be used for the treatment of cavities, especially those that are infected or in which there is a risk of infection. It can also be used for intubation and has been shown to be effective at reducing allergic reactions by blocking the release of histamine by mast cells. Dextran sulfate sodium salt also has kinetic properties and can be used to study enzymatic reactions. This polymer is not toxic because it cannot be absorbed through the skin or gastrointestinal tract.

Fórmula: (C₆H₇Na₃O₁₄S₃)n

Ref: 3D-D-0695