CAS 90332-64-2

10-Desacetil-7-xilosiltaxol B

Descrição:

10-Desacetil-7-xilosiltaxol B, identificado pelo seu número CAS 90332-64-2, é um composto químico que pertence à classe dos taxanos, conhecidos por suas complexas estruturas policíclicas e significativa atividade biológica. Esta substância é caracterizada por sua estrutura molecular única, que inclui um núcleo de taxano modificado pela presença de um grupo xilosil e a ausência de um grupo acetil na posição 10. O composto exibe propriedades farmacológicas notáveis, particularmente no contexto do tratamento do câncer, uma vez que os taxanos são frequentemente utilizados por sua capacidade de inibir a divisão celular estabilizando os microtúbulos. Além disso, a presença do grupo xilosil pode influenciar sua solubilidade e biodisponibilidade, afetando potencialmente sua eficácia terapêutica. Assim como muitos produtos naturais derivados de fontes vegetais, o composto também pode exibir uma variedade de atividades biológicas além de seus efeitos antitumorais, tornando-se um assunto de interesse para futuras pesquisas em química medicinal e farmacologia.

Fórmula: C₄₈H₅₉NO₁₇

InChI: InChI=1S/C48H59NO17/c1-8-23(2)41(57)49-33(26-15-11-9-12-16-26)36(54)43(59)63-29-20-48(60)40(65-42(58)27-17-13-10-14-18-27)38-46(7,39(56)35(53)32(24(29)3)45(48,5)6)30(19-31-47(38,22-62-31)66-25(4)50)64-44-37(55)34(52)28(51)21-61-44/h8-18,28-31,33-38,40,44,51-55,60H,19-22H2,1-7H3,(H,49,57)/b23-8+/t28-,29+,30+,31-,33+,34+,35-,36-,37-,38+,40+,44+,46-,47+,48-/m1/s1

Chave InChI: InChIKey=YAOWLIDDDUBAEI-ZVZSAYPQSA-N

SMILES: O(C(C)=O)[C@]12[C@@]3([C@@](C)([C@@H](O[C@H]4[C@H](O)[C@@H](O)[C@H](O)CO4)C[C@]1(OC2)[H])C(=O)[C@H](O)C=5C(C)(C)[C@](O)([C@H]3OC(=O)C6=CC=CC=C6)C[C@H](OC([C@@H]([C@@H](NC(/C(=C/C)/C)=O)C7=CC=CC=C7)O)=O)C5C)[H]

Sinónimos:

• 7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete, benzenepropanoic acid deriv.
• 10-Deacetylcephalomannine 7-xyloside
• Benzenepropanoic acid, α-hydroxy-β-[(2-methyl-1-oxo-2-butenyl)amino]-, 12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-6,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-(β-D-xylopyranosyloxy)-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, [2aR-[2aα,4β,4aβ,6β,9a[αR*,βS*(E)],11α,12α,12aα,12bα]]-
• Benzenepropanoic acid, α-hydroxy-β-[[(2E)-2-methyl-1-oxo-2-buten-1-yl]amino]-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-6,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-(β-D-xylopyranosyloxy)-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester
• Benzenepropanoic acid, α-hydroxy-β-[[(2E)-2-methyl-1-oxo-2-butenyl]amino]-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-6,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-(β-D-xylopyranosyloxy)-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-
• 7-Xylosyl-10-deacetylcephalomannine
• 10-Deacetyl-7-xylosyltaxol B
• Benzenepropanoic acid, α-hydroxy-β-[[(2E)-2-methyl-1-oxo-2-buten-1-yl]amino]-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-6,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-(β-D-xylopyranosyloxy)-7,11-methano-1H-cyclodeca[3,4]benz[1,2...
• 7-Xylosyl-10-deacetyltaxol B
• DEACETYL-7-XYLOSYLCEPHALOMANNINE, 10-(RG)

DEACETYL-7-XYLOSYLCEPHALOMANNINE, 10-(RG)

CAS: 90332-64-2

Fórmula: C₄₈H₅₉NO₁₇

Pureza: 98%

Peso molecular: 921.9786

Ref: IN-DA00H097

7-Xylosyl-10-deacetyltaxol B

CAS: 90332-64-2

7-Xylosyl-10-deacetyltaxol B (7-xylosyl-10-Deacetylpaclitaxel B) is a paclitaxel derivative with antitumour activity that is used in the synthesis of paclitaxel

Fórmula: C₄₈H₅₉NO₁₇

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 921.98

Ref: TM-TN1335

7-Xylosyl-10-deacetyltaxol B

CAS: 90332-64-2

Fórmula: C₄₈H₅₉NO₁₇

Pureza: 95%~99%

Peso molecular: 921.99

Ref: BP-SBP03711

7-Xylosyl-10-deacetyltaxol B

CAS: 90332-64-2

7-Xylosyl-10-deacetyltaxol B is a natural product derivative, which is a taxoid compound commonly isolated from yew tree species such as Taxus brevifolia. This derivative is structurally adapted from the well-known chemotherapeutic agent paclitaxel. The source, primarily the bark and needles of yew plants, provides a rich repository of taxanes, which are crucial for their cytotoxic properties against cancer cells.

Fórmula: C₄₈H₅₉NO₁₇

Pureza: Min. 95%

Peso molecular: 922 g/mol

Ref: 3D-QDA33264