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CAS 90357-51-0
:N-[4-Ciano-3-(trifluorometil)fenil]-2-metil-2-oxiranocarboxamida
Descrição:
N-[4-Ciano-3-(trifluorometil)fenil]-2-metil-2-oxiranocarboxamida, com o número CAS 90357-51-0, é um composto químico caracterizado por sua estrutura única, que inclui um grupo funcional epóxido (oxirano) e um grupo ciano ligado a um anel fenílico. A presença de um grupo trifluorometílico aumenta sua estabilidade química e lipofilicidade, tornando-o potencialmente útil em várias aplicações, incluindo produtos farmacêuticos e agroquímicos. A funcionalidade epóxica do composto sugere que ele pode participar de reações de abertura de anel, o que pode levar à formação de diversos derivados. Além disso, o grupo ciano pode contribuir para a reatividade e polaridade do composto, influenciando sua solubilidade e interação com sistemas biológicos. No geral, as características distintas deste composto o tornam um assunto de interesse na química sintética e na ciência dos materiais, embora aplicações específicas dependam de mais pesquisas sobre suas propriedades e comportamento em diferentes ambientes.
Fórmula:C12H9F3N2O2
InChI:InChI=1S/C12H9F3N2O2/c1-11(6-19-11)10(18)17-8-3-2-7(5-16)9(4-8)12(13,14)15/h2-4H,6H2,1H3,(H,17,18)
Chave InChI:InChIKey=UQUQTWDUTIAAAY-UHFFFAOYSA-N
SMILES:C(NC1=CC(C(F)(F)F)=C(C#N)C=C1)(=O)C2(C)CO2
Sinónimos:- 1,2-Epoxy-2-Methyl-N-[4-Cyano-3-(Trifluoromethyl)]
- 1,2-Epoxy-2-Methyl-N[4-Cyano-3(Trifluoromethyl)-Phenyl]Propanamide
- 2-Methyl-oxirane-2-carboxylic acid (4-cyano-3-trifluoromethylphenyl)-amide
- 2-Methyloxirane-2-carboxylic acid N-(4-cyano-3-trifluoromethylphenyl)amide
- 2-Oxiranecarboxamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyl-
- 4'-Cyano-3'-trifluoromethyl-2,3-epoxy-2-methylpropioanilide
- Carboxamide
- N-[4-Cyano-3-(Triflouromethyl)Phenyl]-2-Methyl-2-Oxirane Carboxamide
- N-[4-Cyano-3-(Trifluoromethyl)Phenyl]Methacrylamide Epoxide
- N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide
- N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-oxiranecarboxamide
- N-[4-Cyano-3-(trifluoromethyl)phenyl]-methacrylamide exoxide
- N-[4-Cyano-3-Trifluoromethy Phenyl]-2-Oxirane Carboxamide
- N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyl-oxiranecarboxamide
- N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide
- Oxiranecarboxamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyl-
- Phenyl]-2-methyl-2-oxirane
- Ver mais sinónimos
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9 produtos.
Oxiranecarboxamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyl-
CAS:Fórmula:C12H9F3N2O2Pureza:98%Cor e Forma:SolidPeso molecular:270.2073Bicalutamide Impurity 3 (Bicalutamide Epoxide Impurity)
CAS:Fórmula:C12H9F3N2O2Cor e Forma:White To Off-White SolidPeso molecular:270.21N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamide
CAS:N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamidePureza:98%Peso molecular:270.21g/mol1,2-Epoxy-2-methyl-N-[4-cyano-3-(trifluoromethyl)-phenyl]propionamide
CAS:Produto ControladoFórmula:C12H9F3N2O2Cor e Forma:NeatPeso molecular:270.21N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide
CAS:Fórmula:C12H9F3N2O2Pureza:>95.0%(GC)Cor e Forma:White to Almost white powder to crystalPeso molecular:270.21N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide
CAS:Produto ControladoImpurity Bicalutamide Oxirane Impurity / Bicalutamide Epoxide Impurity
Applications N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide, is an intermediate in synthesis of more complex pharmaceutical compounds. It is used in the synthesis of potential impurities of Bicalutamide (B382000), which is an oral nonsteroidal, anti-androgen drug used for prostate cancer.
References Nandu Baban, B., et al.: Synthetic Communications, 39, 1516 (2009);Fórmula:C12H9F3N2O2Cor e Forma:NeatPeso molecular:270.21N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamide
CAS:Fórmula:C12H9F3N2O2Pureza:98%Cor e Forma:SolidPeso molecular:270.211N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide
CAS:N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide (NUOX) is a potential anticancer agent that has been shown to have an acidic pKa of 5.8 and to be active against cancer cells in the same way as bicalutamide, which is a known antiandrogen. NUOX has been shown to increase the number of cavities in polybenzimidazole (PBI) films by enhancing the rate of oxidation. NUOX also inhibits the growth of human cancer cells by binding sulfide groups on proteins and DNA, inhibiting cellular respiration. NUOX is not water soluble, so it must be dissolved in solvents such as acetonitrile or chloroform before administration.Fórmula:C12H9F3N2O2Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:270.21 g/mol
![Oxiranecarboxamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyl-](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA00IG48.jpg&w=3840&q=75)
![1,2-Epoxy-2-methyl-N-[4-cyano-3-(trifluoromethyl)-phenyl]propionamide](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F86%2Fthumb%2FMM0894.11.jpg&w=3840&q=75)
![N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3B%2Fthumb%2FC3607.jpg&w=3840&q=75)
![N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb%2FC987585.jpg&w=3840&q=75)
![N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb%2FIC58274.jpg&w=3840&q=75)
