CAS: 905579-51-3 - Pevonedistat

Fórmula: C₂₁H₂₅N₅O₄S

InChI: InChI=1S/C21H25N5O4S/c22-31(28,29)30-11-14-9-15(10-19(14)27)26-8-7-17-20(23-12-24-21(17)26)25-18-6-5-13-3-1-2-4-16(13)18/h1-4,7-8,12,14-15,18-19,27H,5-6,9-11H2,(H2,22,28,29)(H,23,24,25)/t14-,15+,18-,19-/m0/s1

Chave InChI: InChIKey=MPUQHZXIXSTTDU-QXGSTGNESA-N

SMILES: O=S(=O)(OCC1CC(N2C=CC=3C(=NC=NC32)NC4C=5C=CC=CC5CC4)CC1O)N

Sinónimos:

• MLN 4924
• Pevonedistat
• Sulfamic acid, [(1S,2S,4R)-4-[4-[[(1S)-2,3-dihydro-1H-inden-1-yl]amino]-7H-pyrrolo[2,3-d]pyrimidin-7-yl]-2-hydroxycyclopentyl]methyl ester

Sulfamic acid [(1S,2S,4R)-4-[4-[[(1S)-2,3-dihydro-1H-inden-1-yl]amino]-7H-pyrrolo[2,3-d]pyrimidin-7-yl]-2-hydroxycyclopentyl]methyl ester

CAS: 905579-51-3

• Fórmula: C₂₁H₂₅N₅O₄S
• Pureza: 98%
• Cor e Forma: Solid
• Peso molecular: 443.5193

MLN 4924

CAS: 905579-51-3

• Fórmula: C₂₁H₂₅N₅O₄S
• Pureza: ≥ 98.0%
• Cor e Forma: White solid
• Peso molecular: 443.52

Pevonedistat

CAS: 905579-51-3

Pevonedistat (MLN4924) is a potent and selective NEDD8 activating enzyme (NAE) inhibitor (IC50=4.7 nM).

• Fórmula: C₂₁H₂₅N₅O₄S
• Pureza: 95% - 99.92%
• Cor e Forma: Solid
• Peso molecular: 443.52

MLN 4924

CAS: 905579-51-3

MLN 4924 is an investigational agent that has been shown to inhibit the neddylation of …

• Fórmula: C₂₁H₂₅N₅O₄S
• Pureza: Min. 95%
• Cor e Forma: White Powder
• Peso molecular: 443.52 g/mol

MLN 4924

CAS: 905579-51-3

Applications A potent and selective inhibitor of NAE. An inhibitor of NEDD8-activating enzyme as a …

• Fórmula: C₂₁H₂₅N₅O₄S
• Cor e Forma: Neat
• Peso molecular: 443.52