CAS 9073-60-3

β-Lactamase

Descrição:

β-Lactamase é uma enzima que desempenha um papel crucial na resistência a antibióticos, particularmente contra antibióticos β-lactâmicos como penicilinas e cefalosporinas. É produzida por várias bactérias, incluindo espécies Gram-positivas e Gram-negativas. A função principal do β-Lactamase é hidrolisar o anel β-lactâmico desses antibióticos, tornando-os ineficazes e permitindo que as bactérias sobrevivam na presença desses medicamentos. A enzima apresenta uma variedade de características, incluindo sua capacidade de variar em especificidade e atividade dependendo da cepa bacteriana e do tipo de antibiótico β-lactâmico. Os β-Lactamases podem ser classificados em diferentes grupos com base em sua estrutura molecular e mecanismo de ação, incluindo β-Lactamases de serina e metalo-β-Lactamases. A presença de genes de β-Lactamase em populações bacterianas é uma preocupação significativa em ambientes clínicos, pois contribui para o crescente problema da resistência a antibióticos, tornando as infecções mais difíceis de tratar. Compreender os mecanismos e características dos β-Lactamases é essencial para desenvolver novas estratégias para combater infecções resistentes a antibióticos.

Fórmula: Unspecified

Sinónimos:

• 3: PN: WO2019216248 SEQID: 10 claimed DNA
• Carbapenamase
• Carbapenem hydrolase
• Carbapenem-hydrolyzing β-lactamase
• Carbapenemase
• Carbapenemase 1
• Cefinase
• Cefotaximase
• Ceftazidimase
• Ceftazimidase
• Cefuroximase
• Cephalosporinase
• Cephamycinase
• Cloxacilanase
• Difco Penase
• Difco Penase Concentrate
• E.C. 3.5.2.6
• E.C. 3.5.2.8
• Imipenem-hydrolyzing β-lactamase
• Imipenemase
• Lactamasa, Β-
• Lactamase
• Metallo-β-lactamase
• Metallo-β-lactamases
• Neutrapen
• Oxacillinase
• Oxyiminocephalosporinase
• Penase
• Penicilloyl serine transferase
• Proteins, gene blaZ
• β-Lactamase
• β-Lactamase II
• EC 3.5.2.6
• b-Lactamase, Bacillus cereus 569/H9
• CENTA B-LACTAMASE SUBSTRATE

LacBuster™-L concentrate

CAS: 9073-60-3

Beta-lactamase solution targeting beta-lactam antibiotics such as penicillins, carbapenems and cephalosporins. According to US Pharmacopeia (USP <71>) and EP, LacBusterTM-L is suitable for sterility testing methods such as membrane filtration and direct inoculation.

Ref: 3D-EBL019.7

LacBuster™ (b-lactamase) settle plates

CAS: 9073-60-3

A general purpose growth medium supplemented with LacBuster™ to effectively neutralize beta-lactam antibiotics. This product is suitable for the cultivation of a wide variety of microorganisms for environmental monitoring within the pharmaceutical industry and for high performance monitoring of your isolators and clean rooms during beta lactam manufacture

Ref: 3D-EBL061

LacBuster™-L 1000 (β-lactamase)

CAS: 9073-60-3

Ready to use beta-lactamase solution targeting beta-lactam antibiotics such as penicillins, carbapenems and cephalosporins. According to US Pharmacopeia (USP <71>) and EP, LacBusterTM-L is suitable for sterility testing methods such as membrane filtration and direct inoculation.

Ref: 3D-EBL011.3

OXA-11 (β-Lactamase)

CAS: 9073-60-3

OXA-11 (β-Lactamase) is an enzyme of the β-lactamase class, which is primarily derived from Gram-negative bacteria. This enzyme is characterized by its ability to hydrolyze β-lactam antibiotics, rendering them ineffective by breaking the β-lactam ring, a crucial component of these antibiotics. OXA-11 is a notable member of the oxacillinase group within class D β-lactamases, known for its resistance to penicillins and cephalosporins.

Ref: 3D-EB10013

LacBuster™-L bulk (β-lactamase)

CAS: 9073-60-3

Ready to use beta-lactamase solution targeting beta-lactam antibiotics such as penicillins, carbapenems and cephalosporins. According to US Pharmacopeia (USP <71>) and EP, LacBusterTM-L is suitable for sterility testing methods such as membrane filtration and direct inoculation.

Ref: 3D-EBL010.7

LacBuster™-S bulk (β-Lactamase)

CAS: 9073-60-3

This product shows beta-lactamase activity against clinically relevant beta-lactam antibiotics such as penicillins, carbapenems and cephalosporins. This product may be of particular interest for laboratory teams who require the sterility testing of biological specimens or for environmental monitoring applications.

Ref: 3D-EBL020.5

LacBuster™-S bulk for plates (β-lactamase)

CAS: 9073-60-3

This product shows beta-lactamase activity against clinically relevant beta-lactam antibiotics such as penicillins, carbapenems and cephalosporins. This product may be of particular interest for laboratory teams who require the sterility testing of biological specimens or for environmental monitoring applications.

Ref: 3D-EBL039.5

SPM-1 (β-Lactamase)

CAS: 9073-60-3

SPM-1 (β-Lactamase) is an enzyme, which is a type of metallo-beta-lactamase enzyme, derived from bacterial origins, specifically from pathogens associated with nosocomial infections. This enzyme acts by hydrolyzing the amide bond in the beta-lactam ring of antibiotics, rendering β-lactam antibiotics ineffective. SPM-1 participates in antibiotic resistance by facilitating the degradation of a wide range of β-lactam antibiotics, including penicillins and cephalosporins, thereby nullifying their therapeutic effects.

Ref: 3D-EBL091.5

NMCA (β-Lactamase)

CAS: 9073-60-3

NMCA (β-Lactamase) is an enzyme that hydrolyzes β-lactam antibiotics, a type of product crucial for studies in antibiotic resistance mechanisms. This enzyme is derived from bacterial sources, specifically those strains known for their role in beta-lactam drug resistance. The mode of action of β-Lactamase involves the enzymatic breakdown of the β-lactam ring found in penicillins and cephalosporins, thereby neutralizing the antibiotic's efficacy. This catalytic process is an essential focus for researchers studying bacterial defense mechanisms and the development of resistant strains.

Ref: 3D-EBL096.6

β-Lactamase Kit 01

CAS: 9073-60-3

Beta-lactamase enzymes demonstrate activity against clinically relevant beta-lactam antibiotics such as penicillins, carbapenems and cephalosporins. This product may be of particular interest for laboratory teams who require the sterility testing of biological specimens or for environmental monitoring applications.

Ref: 3D-EBL_KIT01