CAS 90776-58-2

(R)-2-[(3S,4S)-3-[(R)-1-(tert-butil-dimetilsililoxi)etil]-2-oxoazetidin-4-il]ácido propiônico

Descrição:

A substância química conhecida como (R)-2-[(3S,4S)-3-[(R)-1-(tert-butil-dimetilsililoxi)etil]-2-oxoazetidin-4-il]ácido propiônico, com o número CAS 90776-58-2, é um composto quiral que apresenta uma estrutura complexa que inclui um anel de azetidina e um grupo de ácido propiónico. Sua estereoquímica é significativa, pois contém múltiplos centros quirais, que podem influenciar sua atividade biológica e interações. A presença do grupo tert-butyldimethylsilyloxy sugere que este composto pode ser utilizado em química orgânica sintética, particularmente em estratégias de grupos de proteção ou como um intermediário na síntese de moléculas mais complexas. O anel de azetidina contribui para a rigidez do composto e pode afetar suas propriedades farmacocinéticas. Além disso, o componente de ácido propiónico indica aplicações potenciais em química medicinal, possivelmente como um agente farmacêutico. No geral, as características estruturais únicas e a estereoquímica do composto o tornam de interesse em vários campos, incluindo desenvolvimento de medicamentos e síntese orgânica.

Fórmula: C₁₄H₂₇NO₄Si

InChI: InChI=1S/C14H27NO4Si/c1-8(13(17)18)11-10(12(16)15-11)9(2)19-20(6,7)14(3,4)5/h8-11H,1-7H3,(H,15,16)(H,17,18)/t8-,9-,10-,11-/m1/s1

Chave InChI: InChIKey=NNANGMFTFSNDLW-GWOFURMSSA-N

SMILES: [C@@H](C(O)=O)(C)[C@@]1([C@@]([C@H](O[Si](C(C)(C)C)(C)C)C)(C(=O)N1)[H])[H]

Sinónimos:

• (2R)-2-{(2S,3S)-3-[(1R)-1-{[tert-butyl(dimethyl)silyl]oxy}ethyl]-4-oxoazetidin-2-yl}propanoic acid
• (3S 4S)-3-[(R)-1-(T-Butyldimethylsilyloxy)Ethyl]-4-[(R)-1-Carboxyethyl]-2-Azetidinone
• (3S,4S)-3-[(1R)-1-[(tert-Butyldimethylsilyl)oxy]ethyl]-4-((1R)-1-carboxyethyl)azetidin-2-one
• (3S,4S)-3-[(R)-(Butyldimethylsilyloxy)Ethyl]-4-[(R)-Carboxyethyl]-2-Azetidinone
• (3S,4S)-3-[(R)-1-(Tert-Butyldimethylsiloxy)Ethyl]-4-[(R)-1-Carboxyethyl]-2-Azetidinone
• (3S,4S)-3-[(R)-1-(Tert-Butyldimethylsilyloxy)Ethyl]-4-[(R)-1-Carboxyethyl]-2-Azetidinone
• (3S,4S)-4-[(R)-1-carboxy-ethyl]-3-[(R)-1-(t-butyldimethylsilyloxy)ethyl]-2-azetidinone
• (3S,4S)-4-[(R)-1-carboxyethyl]-3-[(R)-1-(t-butyldimethylsilyloxy)ethyl]-2-azetidinone
• (R)-2-((2S,3S)-3-((R)-1-(Tert-Butyldimethylsilyloxy)Ethyl)-4-Oxoazetidin-2-Yl)Propanoic Acid
• (R)-2-[(3S,4S)-3-[(R)-1-(tert-Butyldimethylsilyloxy)ethyl]-2-oxoazetidin-4-yl]propionic acid
• (αR,2S,3S)-3-[(1R)-1-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]ethyl]-α-methyl-4-oxo-2-azetidineacetic acid
• 1-Bma
• 2-Azetidineacetic acid, 3-[(1R)-1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethyl]-α-methyl-4-oxo-, (αR,2S,3S)-
• 2-Azetidineacetic acid, 3-[1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethyl]-α-methyl-4-oxo-, [2S-[2α(S*),3β(S*)]]-
• 4-BMA(for Meropenem)
• 4-Bma
• 4Bma
• Side Chain For Imipenem
• [2R-[2α(R*),3β(R*)] ]-3-[1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethyl]-α-methl-4-oxo-2-azetidineacetic acid

(3S,4S)-4-[(R)-1-carboxyethyl]-3-[(R)-1-(t-butyldimethylsilyloxy)ethyl]-2-azetidinone

CAS: 90776-58-2

Fórmula: C₁₄H₂₇NO₄Si

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 301.4540

Ref: IN-DA003BTJ

(R)-2-((2S,3S)-3-((R)-1-((Tert-Butyldimethylsilyl)Oxy)Ethyl)-4-Oxoazetidin-2-Yl)Propanoic Acid

CAS: 90776-58-2

(R)-2-((2S,3S)-3-((R)-1-((Tert-Butyldimethylsilyl)Oxy)Ethyl)-4-Oxoazetidin-2-Yl)Propanoic Acid

Pureza: 95%

Peso molecular: 301.45g/mol

Ref: 54-OR1008440

(3S 4S)-3-[ (R)-1-(T-Butyldimethylsilyloxy)ethyl]-4[(R)-1-carboxyethyl]-2-azetidinone

CAS: 90776-58-2

S03379 - (3S 4S)-3-[ (R)-1-(T-Butyldimethylsilyloxy)ethyl]-4[(R)-1-carboxyethyl]-2-azetidinone

Fórmula: C₁₄H₂₇NO₄Si

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 301.458

Ref: 10-S03379

(3S,4S)-3-((R)-(tert-Butyldimethyl-silyloxy)ethyl)-4((R)-carboxyethyl)-2-azetidinone

CAS: 90776-58-2

(3S,4S)-3-((R)-(tert-Butyldimethyl-silyloxy)ethyl)-4((R)-carboxyethyl)-2-azetidinone (SBET) is a propionylated carbapenem antibiotic. It is an analog of ertapenem, a carbapenem antibiotic that has been developed for the treatment of multidrug resistant Gram-negative bacteria. SBET has been shown to have stereospecificity in vitro studies and to be metabolized by organic acids. The reaction yields are dependent on the solvents used. The functional groups on SBET are important for its activity as a carbapenem antibiotic.

Fórmula: C₁₄H₂₇NO₄Si

Pureza: Min. 95%

Peso molecular: 301.45 g/mol

Ref: 3D-FB149807