CAS 911-40-0

Ácido 7-cetodesoxicólico

Descrição:

Ácido 7-cetodesoxicólico, também conhecido como 7-keto-DCA, é um derivado de ácido biliar caracterizado pela presença de um grupo cetona na posição C7 do núcleo esteroide. É um sólido branco a off-white que é solúvel em solventes orgânicos, mas tem solubilidade limitada em água. Este composto é um metabolito do ácido desoxicólico e desempenha um papel em vários processos biológicos, incluindo o metabolismo de lipídios e a emulsificação de gorduras. Sua estrutura apresenta uma espinha dorsal esteroide, que é típica dos ácidos biliares, e exibe propriedades anfipáticas, permitindo que interaja com ambientes hidrofílicos e hidrofóbicos. Ácido 7-cetodesoxicólico despertou interesse na pesquisa por suas potenciais aplicações terapêuticas, particularmente no contexto de distúrbios metabólicos e obesidade. Além disso, pode influenciar vias de sinalização celular e foi estudado por seus efeitos no metabolismo do colesterol. Assim como muitos ácidos biliares, sua atividade biológica está intimamente ligada à sua concentração e à presença de outros ácidos biliares no trato gastrointestinal.

Fórmula: C₂₄H₃₈O₅

InChI: InChI=1/C24H38O5/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26/h13-18,20,22,25,27H,4-12H2,1-3H3,(H,28,29)/t13-,14+,15-,16-,17+,18+,20+,22+,23+,24-/m1/s1

Chave InChI: InChIKey=RHCPKKNRWFXMAT-RRWYKFPJSA-N

SMILES: O=C1[C@]2([C@]3([C@@](C)([C@@]([C@@H](CCC(O)=O)C)(CC3)[H])[C@@H](O)C[C@@]2([C@]4(C)[C@](C1)(C[C@H](O)CC4)[H])[H])[H])[H]

Sinónimos:

• (3a,5b,12a)-3,12-dihydroxy-7-oxo-Cholan-24-oic acid
• (3α,5β,12α)-3,12-Dihydroxy-7-oxocholan-24-oic acid
• 3A,12A-Dihydroxy-7-Oxo-5B-Cholan-24-Oic Acid
• 3α,12α-Dihydroxy-7-keto-5β-cholanic acid
• 3α,12α-Dihydroxy-7-ketocholanic acid
• 3α,12α-Dihydroxy-7-oxo-5β-cholanoic acid
• 5β-Cholan-24-oic acid, 3α,12α-dihydroxy-7-oxo-
• 5β-Cholanic acid, 3α,12α-dihydroxy-7-oxo-
• 5β-Cholanic acid-3α,12α-diol-7-one
• 7-Ketodeoxycholic acid
• 7-Oxo-3α,12α-dihydroxy-5β-cholanoic acid
• 7-Oxo-3α,12α-dihydroxycholan-24-oic acid
• 7-Oxodeoxycholic acid
• 7-keto-3α,12α-Dihydroxy-5β-cholanic acid
• 7-keto-Deoxycholic acid
• Cholan-24-Oic Acid, 3,12-Dihydroxy-7-Oxo-, (3Alpha,5Beta,12Alpha)-
• Cholan-24-oic acid, 3,12-dihydroxy-7-oxo-, (3α,5β,12α)-
• 5-BETA-CHOLANIC ACID-3-ALPHA, 12-ALPHA-DIOL-7-ONE
• 3,12-DIHYDROXY-7-OXOCHOLAN-24-OIC ACID
• 3α,12α-dihydroxy-7-keto-5β-cholan-24-oic acid
• 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanic acid
• Deoxycholic Acid 7-Oxo Impurity
• 7-Ketodeoxycholic acida
• Ursodeoxycholic Acid Impurity 11
• 7-Keto-3alpha,12alpha-dihydroxycholanic acid
• 7-DEHYDROCHOLIC ACID

7-keto Deoxycholic Acid

CAS: 911-40-0

Fórmula: C₂₄H₃₈O₅

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 406.5555

Ref: IN-DA006QNT

Cholic Acid Impurity 12 (7-Ketodeoxy Cholic Acid)

CAS: 911-40-0

Fórmula: C₂₄H₃₈O₅

Peso molecular: 406.56

Ref: 4Z-C-57119

7-Keto-3Α,12-Α-Dihydroxycholanic Acid

CAS: 911-40-0

7-Keto-3Α,12-Α-Dihydroxycholanic Acid

Pureza: 97%

Peso molecular: 406.57g/mol

Ref: 54-OR1026113

7-keto-deoxycholic acid

CAS: 911-40-0

7-keto-deoxycholic acid is converted from Lactobacillus and Bifidobacterium with specific condition and from cholic acid in vitro.

Fórmula: C₂₄H₃₈O₅

Pureza: 99.63% - 99.63%

Cor e Forma: Solid

Peso molecular: 406.56

Ref: TM-TN7120

7-keto-deoxycholic acid

CAS: 911-40-0

7-keto-deoxycholic acid

Pureza: ≥98%

Peso molecular: 406.56g/mol

Ref: 54-BUP15614

7-oxo-Deoxycholic acid

CAS: 911-40-0

Fórmula: C24H38O5

Pureza: >96%

Cor e Forma: Solid

Peso molecular: 406.56

Ref: 48-65-1117

7-Keto-3α,12-α-dihydroxycholanic Acid

Produto Controlado

CAS: 911-40-0

Fórmula: C₂₄H₃₈O₅

Cor e Forma: Off White Solid

Peso molecular: 406.56

Ref: TR-K188480

7-Keto-3α,12-α-dihydroxycholanic acid

Produto Controlado

CAS: 911-40-0

7-Keto-3α,12-α-dihydroxycholanic acid is a lipid molecule that belongs to the class of sodium salts. It has been shown to form stable complexes with biological samples and is useful for sample preparation before analysis. 7-Keto-3α,12-α-dihydroxycholanic acid has been used in studies of hepatic steatosis in rats, which demonstrated statistically significant changes in liver fat content. This molecule also may be involved in bowel disease because it is a precursor for bile acids and the synthesis of cholesterol. 7KDHC has been associated with redox potential and microbial metabolism. 7KDHC may also have anti-inflammatory effects that help reduce symptoms of inflammatory bowel disease (IBD).

Fórmula: C₂₄H₃₈O₅

Pureza: Min. 95 Area-%

Cor e Forma: White Powder

Peso molecular: 406.56 g/mol

Ref: 3D-FK24796

7-Ketodeoxycholic acid

CAS: 911-40-0

Fórmula: C₂₄H₃₈O₅

Peso molecular: 406.56

Ref: ST-EA-CP-U1016

7-Ketodeoxycholic Acid

CAS: 911-40-0

Fórmula: C₂₄H₃₈O₅

Peso molecular: 406.56

Ref: ST-EA-CP-C93031