CAS 914934-02-4

2-Hydroxy Estradiol 1-N3-Adenine

Produto Controlado

CAS: 914934-02-4

Applications 2-Hydroxy Estradiol 1-N3-Adenine is an estrogen metabolite formed with DNA which can lead to the mutations that initiate breast, prostate, and other types of cancer. The N3Ade depurinating adducts could serve as biomarkers to predict the risk of breast cancer.
References Chakravarti, D., et al.: Mutat. Res., 456, 17 (2000), Liehr, J., et al.: Endocr. Rev., 21, 4054 (2000), Chakravarti, D., et al.: Oncogene, 20, 7945 (2001), Cavalieri, E., et al.: Chem. Res. Toxicol., 14, 1041 (2002), Paula, M. et al.: J Steroid Biochem. Mol. Biol., 101, 204 (2006);

Fórmula: C₂₃H₂₇N₅O₃

Cor e Forma: Neat

Peso molecular: 421.492

Ref: TR-H942103