CAS 92823-03-5

Flomoxef sódico

Descrição:

Flomoxef sódico é um antibiótico cefalosporínico de amplo espectro, utilizado principalmente por suas propriedades antibacterianas. É eficaz contra uma variedade de bactérias Gram-positivas e Gram-negativas, tornando-o útil no tratamento de infecções causadas por esses patógenos. O composto é caracterizado por sua capacidade de resistir à hidrólise por certas beta-lactamases, o que aumenta sua eficácia contra cepas bacterianas resistentes. Flomoxef sódico é tipicamente administrado por injeção e é conhecido por seu perfil de toxicidade relativamente baixo. Sua farmacocinética inclui boa penetração nos tecidos e uma meia-vida favorável, permitindo esquemas de dosagem eficazes. A substância é frequentemente utilizada em ambientes clínicos para tratar infecções do trato respiratório, infecções do trato urinário e infecções de pele. Assim como qualquer antibiótico, o potencial de desenvolvimento de resistência exige uma consideração cuidadosa de seu uso, e é importante seguir as diretrizes para a prescrição adequada para mitigar esse risco. No geral, Flomoxef sódico representa uma opção valiosa no arsenal de terapias antimicrobianas.

Fórmula: C₁₅H₁₈F₂N₆O₇S₂·Na

InChI: InChI=1S/C15H18F2N6O7S2.Na/c1-29-15(18-8(25)6-31-13(16)17)11(28)23-9(10(26)27)7(4-30-12(15)23)5-32-14-19-20-21-22(14)2-3-24;/h12-13,24H,2-6H2,1H3,(H,18,25)(H,26,27);/t12-,15+;/m1./s1

Chave InChI: InChIKey=SYHZUFMYQQRMKT-YLCXCWDSSA-N

SMILES: N(C(CSC(F)F)=O)[C@@]1(OC)[C@@]2(N(C1=O)C(C(O)=O)=C(CSC=3N(CCO)N=NN3)CO2)[H].[Na]

Sinónimos:

• 5-Oxa-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((((difluoromethyl)thio)acetyl)amino)-3-(((1-(2-hydroxyethyl)-1H-tetrazol-5-yl)thio)methyl)-7-methoxy-8-oxo-, monosodium salt, cis-
• 5-Oxa-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(2-((difluoromethyl)thio)acetamido)-3-(((1-(2-hydroxyethyl)-1H-tetrazol-5-yl)thio)methyl)-7-methoxy-8-oxo-, sodium salt,(6R,7R)-
• 5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[(difluoromethyl)thio]acetyl]amino]-3-[[[1-(2-hydroxyethyl)-1H-tetrazol-5-yl]thio]methyl]-7-methoxy-8-oxo-, monosodium salt, (6R,7R)-
• 5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[(difluoromethyl)thio]acetyl]amino]-3-[[[1-(2-hydroxyethyl)-1H-tetrazol-5-yl]thio]methyl]-7-methoxy-8-oxo-, monosodium salt, (6R-cis)-
• 5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[(difluoromethyl)thio]acetyl]amino]-3-[[[1-(2-hydroxyethyl)-1H-tetrazol-5-yl]thio]methyl]-7-methoxy-8-oxo-, sodium salt (1:1), (6R,7R)-
• 6315 S Shionogi
• 6315S
• Flomoxef sodium salt
• Flumarin
• sodium (6R,7R)-7-({[(difluoromethyl)sulfanyl]acetyl}amino)-3-({[1-(2-hydroxyethyl)-1H-tetrazol-5-yl]sulfanyl}methyl)-7-methoxy-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

Flomoxef sodium

CAS: 92823-03-5

Fórmula: C₁₅H₁₇F₂N₆NaO₇S₂

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 518.4481

Ref: IN-DA00GRA2

Flomoxef Sodium Salt

CAS: 92823-03-5

Fórmula: C₁₅H₁₇F₂N₆O₇S₂·Na

Cor e Forma: White To Off-White Solid

Peso molecular: 495.45 22.99

Ref: 4Z-F-107001

Flomoxef Sodium

Produto Controlado

CAS: 92823-03-5

Stability Hygroscopic
Applications Flomoxef Sodium is a sodium salt derivative of Flomoxef (F401850); an oxacephem derived beta-lactam antibiotic that is particularly effective against gram-positive bacteria.
References Miwa, H. et al.: Chemotherapy, 35, 121 (1987); Mikamo, H. et al.: Curr. Therap. Res., 56, 873 (1995);

Fórmula: C₁₅H₁₇F₂N₆NaO₇S₂

Cor e Forma: Neat

Peso molecular: 518.45

Ref: TR-F403000

Flomoxef Sodium - Bio-X ™

CAS: 92823-03-5

Flomoxef sodium is a water-soluble second/fourth-generation cephalosporin, Shionogi β-lactam antibiotic. Flomoxef inhibits bacterial growth through inhibition of cell wall biosynthesis. It has been shown to be effective against infections caused by Streptococcus pneumoniae, Enterobacter aerogenes, and Acinetobacter baumannii among other bacteria, and can be used to treat ongoing infections or as a prophylactic for example ahead of surgery. Flomoxef sodium has been shown to have synergistic effects when used in combination with isepamicin sulfate and penicillin, which may be due to its ability to increase the permeability of the bacterial cell membrane. Clinical trials are currently underway for flomoxef sodium as a treatment for MRSA infections and UTIs. 
Flomoxef Sodium is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Fórmula: C₁₅H₁₈F₂N₆O₇S₂•Na

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 519.46 g/mol

Ref: 3D-BF300080

Flomoxef Sodium

CAS: 92823-03-5

Flomoxef sodium is a water-soluble prodrug with antibacterial activity that is converted to the active form, flomoxef. Flomoxef sodium inhibits bacterial growth by binding to penicillin-binding proteins and inhibiting cell wall synthesis. It has been shown to be effective against infections caused by Streptococcus pneumoniae, Enterobacter aerogenes, and Acinetobacter baumannii. Flomoxef sodium has been shown to have synergistic effects when used in combination with isepamicin sulfate and penicillin, which may be due to its ability to increase the permeability of the bacterial cell membrane. Clinical trials are currently underway for flomoxef sodium as a treatment for MRSA infections.

Fórmula: C₁₅H₁₇F₂N₆NaO₇S₂

Cor e Forma: White Powder

Peso molecular: 518.45 g/mol

Ref: 3D-FF41634

Flomoxef sodium

CAS: 92823-03-5

Flomoxef sodium, an antibiotic belonging to the oxacephem group, exhibits excellent activity against a broad spectrum of Gram-positive bacteria.

Fórmula: C₁₅H₁₇F₂N₆NaO₇S₂

Pureza: 99.28%

Cor e Forma: Solid

Peso molecular: 518.44

Ref: TM-T11301L

Flomoxef Sodium Salt

CAS: 92823-03-5

Fórmula: C₁₅H₁₇F₂N₆O₇S₂Na

Peso molecular: 495.45 : 23.0

Ref: ST-EA-CP-F143003