CAS 93957-55-2
:Fluvastatina sódica
Descrição:
Fluvastatina sódica é um agente sintético redutor de lipídios que pertence à classe das estatinas, utilizado principalmente para gerenciar a hiperlipidemia e reduzir o risco de doenças cardiovasculares. Funciona como um inibidor da HMG-CoA redutase, que desempenha um papel crucial na biossíntese do colesterol. O composto é caracterizado por sua capacidade de reduzir os níveis de colesterol de lipoproteínas de baixa densidade (LDL) enquanto aumenta modestamente o colesterol de lipoproteínas de alta densidade (HDL). Fluvastatina sódica é tipicamente administrado por via oral e é bem absorvido no trato gastrointestinal, embora sua biodisponibilidade seja afetada pelo metabolismo de primeira passagem no fígado. O medicamento geralmente é bem tolerado, mas os efeitos colaterais potenciais podem incluir dor muscular, anormalidades nas enzimas hepáticas e distúrbios gastrointestinais. É contraindicado em pacientes com doença hepática ativa ou aqueles que estão grávidas ou amamentando. Fluvastatina sódica é frequentemente prescrito em conjunto com modificações dietéticas e mudanças no estilo de vida para aumentar sua eficácia no manejo do colesterol. O monitoramento regular dos níveis de lipídios e testes de função hepática é recomendado durante o tratamento.
Fórmula:C24H26FNO4·Na
InChI:InChI=1/C24H26FNO4.Na/c1-15(2)26-21-6-4-3-5-20(21)24(16-7-9-17(25)10-8-16)22(26)12-11-18(27)13-19(28)14-23(29)30;/h3-12,15,18-19,27-28H,13-14H2,1-2H3,(H,29,30);/b12-11+;/t18-,19-;/s2
Chave InChI:InChIKey=CUOKYGJQSIKNFS-ZADPHQEYNA-N
SMILES:C(=C/[C@@H](C[C@@H](CC(O)=O)O)O)\C1=C(C=2C(N1C(C)C)=CC=CC2)C3=CC=C(F)C=C3.[Na]
Sinónimos:- (3R,5S,6E)-rel-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid monosodium salt
- 6-Heptenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-, monosodium salt, (3R,5S,6E)-rel-
- 6-Heptenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-, monosodium salt, [R*,S*-(E)]-(±)-
- 6-Heptenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-, sodium salt (1:1), (3R,5S,6E)-rel-
- Almastatin
- Canef
- Cranoc
- Fluindostatin
- Fluvastatin Sodium Salt
- Fractal
- Lescol
- Lescol XL
- Lochol
- Locol
- Sodium (3R,5S,6E)-7-[3-(4-Fluorophenyl)-1-(1-Methylethyl)-1H-Indol-2-Yl]-3,5-Dihydroxy-6-Heptenoate
- Vastin
- Xu 62-320
- sodium (3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoate
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19 produtos.
Fluvastatin Sodium Salt
CAS:Fórmula:C24H25FNNaO4Pureza:>98.0%(HPLC)(N)Cor e Forma:Light orange to Yellow to Green powder to crystalPeso molecular:433.46FLUVASTATIN SODIUM CRS
CAS:FLUVASTATIN SODIUM CRSFórmula:C24H25FNNaO4Cor e Forma:White. Orange. Light Yellow. Powder.Peso molecular:433.4478FLUVASTATIN FOR SYSTEM SUITABILITY CRS
CAS:FLUVASTATIN FOR SYSTEM SUITABILITY CRSFórmula:C24H25FNNaO4Peso molecular:433.4478Fluvastatin sodium
CAS:Fluvastatin sodiumFórmula:C24H25NNaO4Pureza:97.4%Cor e Forma:Light Yellow. To. OrangePeso molecular:414.16813Fluvastatin Sodium
CAS:Cardiovascular drugs, not elsewhere specified or includedFórmula:C24H25FNNaO4Cor e Forma:White Yellow PowderPeso molecular:433.16653sodium (3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoate
CAS:Fórmula:C24H25FNNaO4Pureza:98%Cor e Forma:SolidPeso molecular:433.4478Fluvastatin sodium
CAS:Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterolFórmula:C24H25FNNaO4Pureza:98.54% - 99.56%Cor e Forma:Light Yellow Solid PowderPeso molecular:433.45Fluvastatin-d6 Sodium Salt
CAS:Fórmula:C24H19D6FNO4·NaCor e Forma:Off-White SolidPeso molecular:416.50 22.99Fluvastatin sodium salt
CAS:Fórmula:C24H25FNO4·Na·xH2OPureza:98.0 - 102.0 % (anhydrous basis)Cor e Forma:Off-white to pale yellow or light yellow-orange powderPeso molecular:433.45 (anhydrous)Fluvastatin Sodium Salt(Relative Stereochemistry)
CAS:<p>Stability Hygroscopic<br>Applications A synthetic HMG-CoA reductase inhibitor. Antilipemic.<br>References Yuan, J., et al.: Atherosclerosis, 87, 147 (1991), Tse, F.L.S., et al.: J. Clin. Pharmacol., 32, 630 (1992), Dain, J.G., et al.: Drug Metab. Disposit., 21, 567 (1993);<br></p>Fórmula:C24H25FNO4·NaCor e Forma:NeatPeso molecular:433.45Fluvastatin-d6 Sodium
CAS:Produto Controlado<p>Applications Fluvastatin-d6 Sodium Salt is the labeled analogue of Fluvastatin Sodium Salt (F601250), a synthetic HMG-CoA reductase inhibitor. Antilipemic.<br>References Yuan, J., et al.: Atherosclerosis, 87, 147 (1991), Tse, F.L.S., et al.: J. Clin. Pharmacol., 32, 630 (1992), Dain, J.G., et al.: Drug Metab. Disposit., 21, 567 (1993);<br></p>Fórmula:C24H19D6FNNaO4Cor e Forma:NeatPeso molecular:439.48Fluvastatin sodium
CAS:<p>Fluvastatin is a statin that lowers blood cholesterol and triglycerides by inhibiting HMG-CoA reductase, an enzyme that plays a critical role in the synthesis of cholesterol. Fluvastatin has also been shown to reduce the incidence of myocardial infarction, and to reduce atherosclerotic lesions in animal models, reducing the incidence of cardiovascular disease. Fluvastatin also has been shown to inhibit the activation of toll-like receptor 4 (TLR4) by lipopolysaccharide (LPS), which may be related to its anti-inflammatory effects. Furthermore, through lowering blood cholesterol, Fluvastatin also inhibits tubulointerstitial injury and prevents renal damage caused by high concentrations of the lipid.</p>Fórmula:C24H25FNNaO4Pureza:Min. 98%Cor e Forma:Off-White PowderPeso molecular:433.45 g/molFluvastatin sodium salt - Bio-X ™
CAS:Fluvastatin is a statin that lowers blood cholesterol and triglycerides by inhibiting HMG-CoA reductase, an enzyme that plays a critical role in the synthesis of cholesterol. Fluvastatin has also been shown to reduce the incidence of myocardial infarction, and to reduce atherosclerotic lesions in animal models, reducing the incidence of cardiovascular disease. Fluvastatin also has been shown to inhibit the activation of toll-like receptor 4 (TLR4) by lipopolysaccharide (LPS), which may be related to its anti-inflammatory effects. Furthermore, through lowering blood cholesterol, Fluvastatin also inhibits tubulointerstitial injury and prevents renal damage caused by high concentrations of the lipid.Fórmula:C24H25FNNaO4Pureza:Min. 98%Peso molecular:433.45 g/mol
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