CAS: 952021-60-2 - PF 00477736

Fórmula: C₂₂H₂₅N₇O₂

InChI: InChI=1S/C22H25N7O2/c1-29-11-13(9-25-29)20-16-10-24-28-21(30)15-7-14(8-17(27-20)18(15)16)26-22(31)19(23)12-5-3-2-4-6-12/h7-12,19,27H,2-6,23H2,1H3,(H,26,31)(H,28,30)/t19-/m1/s1

Chave InChI: InChIKey=NDEXUOWTGYUVGA-LJQANCHMSA-N

SMILES: O=C1NN=CC2=C(NC=3C=C(C=C1C32)NC(=O)C(N)C4CCCCC4)C=5C=NN(C5)C

Sinónimos:

• (αR)-α-Amino-N-[5,6-dihydro-2-(1-methyl-1H-pyrazol-4-yl)-6-oxo-1H-pyrrolo[4,3,2-ef][2,3]benzodiazepin-8-yl]cyclohexaneacetamide
• (R)-2-Amino-2-cyclohexyl-N-(2-(1-methyl-1H-pyrazol-4-yl)-6-oxo-5,6-dihydro-1H-[1,2]diazepino[4,5,6-cd]indol-8-yl)acetamide
• PF 00477736
• (αR)-α-AMino-N-[5,6-dihydro-2-(1-Methyl-1H-pyrazol-4-yl)-6-oxo-1H-pyrrolo[4,3,2-ef][2,3]benzodiazepin-8-yl]cyclohexaneacetaMide
• (R)-2-Amino-2-cyclohexyl-N-(5-(1-methyl-1H-pyrazol-4-yl)-1-oxo-2,6-dihydro-1H-[1,2]diazepino[4,5,6-cd]indol-8-yl)acetamide
• PF 477736
• Cyclohexaneacetamide, α-amino-N-[5,6-dihydro-2-(1-methyl-1H-pyrazol-4-yl)-6-oxo-1H-pyrrolo[4,3,2-ef][2,3]benzodiazepin-8-yl]-, (αR)-

PF-477736

CAS: 952021-60-2

• Fórmula: C₂₂H₂₅N₇O₂
• Pureza: 97%
• Cor e Forma: Solid
• Peso molecular: 419.4796

PF-477736

CAS: 952021-60-2

• Fórmula: C₂₂H₂₅N₇O₂
• Peso molecular: 419.48

PF 477736

CAS: 952021-60-2

PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) …

• Fórmula: C₂₂H₂₅N₇O₂
• Pureza: 98% - 98.34%
• Cor e Forma: Solid
• Peso molecular: 419.48

PF 477736

CAS: 952021-60-2

PF 477736 is a chemical inhibitor of the checkpoint kinase 1 (Chk1) that blocks DNA …

• Fórmula: C₂₂H₂₅N₇O₂
• Pureza: Min. 95%
• Peso molecular: 419.48 g/mol