CAS: 957054-33-0 - Thieno[3,2-d]pyrimidine, 2-(1H-indazol-4-yl)-6-[[4-(methylsulfonyl)-1-piperazinyl]methyl]-4-(4-morpholinyl)-, methanesulfonate (1:2)

Fórmula: C₂₃H₂₇N₇O₃S₂·2CH₄O₃S

InChI: InChI=1S/C23H27N7O3S2.CH4O3S/c1-35(31,32)30-7-5-28(6-8-30)15-16-13-20-21(34-16)23(29-9-11-33-12-10-29)26-22(25-20)17-3-2-4-19-18(17)14-24-27-19;1-5(2,3)4/h2-4,13-14H,5-12,15H2,1H3,(H,24,27);1H3,(H,2,3,4)

Chave InChI: InChIKey=OZRVQTBMLHRDIR-UHFFFAOYSA-N

SMILES: O=S(=O)(O)C.O=S(=O)(N1CCN(CC=2SC3=C(N=C(N=C3N4CCOCC4)C=5C=CC=C6NN=CC65)C2)CC1)C

Sinónimos:

• 2-(1H-Indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine
• 2-(1H-Indazol-4-yl)-6-[[4-(methylsulfonyl)-1-piperazinyl]methyl]-4-(4-morpholinyl)thieno[3,2-d]pyrimidine
• Gdc-0941
• Thieno[3,2-d]pyrimidine, 2-(1H-indazol-4-yl)-6-[[4-(methylsulfonyl)-1-piperazinyl]methyl]-4-(4-morpholinyl)-, methanesulfonate (1:2)

Pictilisib dimethanesulfonate

CAS: 957054-33-0

Pictilisib dimethanesulfonate (GDC-0941 2 MeSO3H salt) is a potent inhibitor of PI3Kα/δ with IC50 of …

• Fórmula: C₂₅H₃₅N₇O₉S₄
• Pureza: 99.63%
• Cor e Forma: Solid
• Peso molecular: 705.85

4-(2-(1H-indazol-4-yl)-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)thieno[3,2-d]pyrimidin-4-yl)morpholine dimethanesulfonate

CAS: 957054-33-0

• Fórmula: C₂₅H₃₅N₇O₉S₄
• Pureza: 98%
• Cor e Forma: Solid
• Peso molecular: 705.8469

GDC-0941 Bimesylate

CAS: 957054-33-0

Applications Potent inhibitor of Phosphatidylinositol 3-kinase (PI3K)

• Fórmula: C₂₃H₂₇N₇O₃S₂· 2(CH₄O₃S)
• Cor e Forma: Light Yellow Solid
• Peso molecular: 705.85

GDC 0941 bimesylate

CAS: 957054-33-0

Pan-PI3K inhibitor of class I catalytic subunits; anti-proliferative

• Fórmula: C₂₅H₃₅N₇O₉S₄
• Pureza: Min. 95%
• Peso molecular: 705.85 g/mol