CAS 960404-48-2

(1S)-1,5-Anidro-1-C-[4-cloro-3-[(4-etoxifenil)metil]fenil]-D-glucitol (S)-propano-1,2-diol (1:1) monohidrato

Descrição:

(1S)-1,5-Anidro-1-C-[4-cloro-3-[(4-etoxifenil)metil]fenil]-D-glucitol (S)-propano-1,2-diol (1:1) monohidrato, com número CAS 960404-48-2, é um composto orgânico complexo caracterizado por sua estereoquímica específica e grupos funcionais. Esta substância apresenta uma estrutura de glucitol, que é um álcool de açúcar, indicando potencial solubilidade em água e relevância biológica. A presença de um grupo cloro e um moiety etoxifenílico sugere que pode exibir propriedades eletrônicas únicas e potenciais interações com alvos biológicos. A forma de monoidratado indica que contém uma molécula de água por unidade de fórmula, o que pode influenciar sua estabilidade, solubilidade e comportamento de cristalização. Compostos desse tipo são frequentemente estudados por suas propriedades farmacológicas, e sua complexidade estrutural pode contribuir para diversas atividades biológicas. No geral, as características deste composto o tornam um assunto de interesse em química medicinal e desenvolvimento de medicamentos, particularmente no contexto do design de terapias com mecanismos de ação específicos.

Fórmula: C₂₁H₂₅ClO₆·C₃H₈O₂·H₂O

InChI: InChI=1S/C21H25ClO6.C3H8O2.H2O/c1-2-27-15-6-3-12(4-7-15)9-14-10-13(5-8-16(14)22)21-20(26)19(25)18(24)17(11-23)28-21;1-3(5)2-4;/h3-8,10,17-21,23-26H,2,9,11H2,1H3;3-5H,2H2,1H3;1H2/t17-,18-,19+,20-,21+;3-;/m10./s1

Chave InChI: InChIKey=GOADIQFWSVMMRJ-UPGAGZFNSA-N

SMILES: O[C@H]1[C@@H](O[C@H](CO)[C@@H](O)[C@@H]1O)C2=CC(CC3=CC=C(OCC)C=C3)=C(Cl)C=C2.[C@@H](CO)(C)O.O

Sinónimos:

• (1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-<span class="text-smallcaps">D</span>-glucitol (S)-propane-1,2-diol (1:1) monohydrate
• <span class="text-smallcaps">D</span>-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-, (1S)-, compd. with (2S)-1,2-propanediol (1:1), monohydrate
• <span class="text-smallcaps">D</span>-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-, (1S)-, compd. with (2S)-1,2-propanediol, hydrate (1:1:1)
• Dapagliflozin (S)-propylene glycol hydrate
• Dapagliflozin Propylene Glycolate Hydrate
• Edistride
• Farxiga
• Forxiga
• D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-, (1S)-, compd. with (2S)-1,2-propanediol (1:1), monohydrate
• D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-, (1S)-, compd. with (2S)-1,2-propanediol, hydrate (1:1:1)
• (1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol (S)-propane-1,2-diol (1:1) monohydrate

DAPAGLIFLOZIN PROPYLENE GLYCOL MONOHYDRATE CRS

CAS: 960404-48-2

DAPAGLIFLOZIN PROPYLENE GLYCOL MONOHYDRATE CRS

Ref: 41-Y0002487

Dapagliflozin Propanediol

CAS: 960404-48-2

Aromatic heterocyclic compounds with oxygen hetero-atom(s) only, nesoi

Fórmula: C₂₁H₂₅ClO₆·C₃H₈O₂·H₂O

Cor e Forma: White Off-White Powder

Peso molecular: 502.19696

Ref: 45-1163253

D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-, (1S)-, compd. with (2S)-1,2-propanediol, hydrate (1:1:1)

CAS: 960404-48-2

Fórmula: C₂₄H₃₅ClO₉

Pureza: 99%

Cor e Forma: Solid

Peso molecular: 502.9823

Ref: IN-DA00IMNP

Dapagliflozin propanediol monohydrate

CAS: 960404-48-2

Fórmula: C₂₁H₂₅ClO₆·C₃H₈O₂·H₂O

Pureza: ≥ 98.0%

Cor e Forma: White to yellow or beige powder or solid

Peso molecular: 502.98

Ref: 7W-GP6243

Dapagliflozin ((2S)-1,2-propanediol, hydrate)

CAS: 960404-48-2

Dapagliflozin ((2S)-1,2-propanediol, hydrate)

Pureza: ≥98%

Peso molecular: 502.98g/mol

Ref: 54-BUP13707

Dapagliflozin Propanediol Hydrate

CAS: 960404-48-2

Dapagliflozin Propanediol Hydrate

Pureza: 99%

Peso molecular: 502.98g/mol

Ref: 54-OR1029987

Dapagliflozin (2S)-1,2-Propanediol Monohydrate

CAS: 960404-48-2

Fórmula: C₂₁H₂₅ClO₆·C₃H₈O₂·H₂O

Cor e Forma: Neat

Peso molecular: 502.98

Ref: 86-MM3611.00

Dapagliflozin ((2S)-1,2-propanediol, hydrate)

CAS: 960404-48-2

Dapagliflozin ((2S)-1,2-propanediol, hydrate) (BMS-512148 (2S)-1,2-propanediol, hydrate) is a selective, orally active inhibitor of the renal sodium-glucose co-

Fórmula: C₂₄H₃₅ClO₉

Pureza: 99.88% - 99.94%

Cor e Forma: Solid

Peso molecular: 502.98

Ref: TM-T4460

(2S,3R,4R,5S,6R)-2-(4-CHLORO-3-(4-ETHOXYBENZYL)PHENYL)-6-(HYDROXYMETHYL)TETRAHYDRO-2H-PYRAN-3,4,5-TRIOL COMPOUND WITH (S)-PROPANE-1,2-DIOL (1:1) HYDRATE

CAS: 960404-48-2

Pureza: 95%

Peso molecular: 502.989990234375

Ref: 10-F796757

Dapagliflozin Propanediol Hydrate

CAS: 960404-48-2

Fórmula: C₂₁H₂₅ClO₆·C₃H₈O₂·H₂O

Cor e Forma: Neat

Peso molecular: 502.98

Ref: TR-D185398

Dapagliflozin propanediol monohydrate

CAS: 960404-48-2

Dapagliflozin is an oral antidiabetic drug that acts by inhibiting the SGLT2 enzyme. The SGLT2 enzyme is responsible for reabsorbing glucose from the kidney, so by inhibiting this enzyme, glucose will be excreted in the urine and blood glucose levels will decrease. Dapagliflozin also has a low bioavailability in vivo, which can be improved by administration with food. This drug has been shown to have a longer elimination half-life than canagliflozin and empagliflozin. Dapagliflozin has been shown to have a higher potency than metformin hydrochloride in vitro.

Fórmula: C₂₄H₃₅ClO₉

Pureza: (Hplc) Min. 99.0%

Cor e Forma: Powder

Peso molecular: 502.98 g/mol

Ref: 3D-MD45346

Dapagliflozin propanediol monohydrate - Bio-X ™

CAS: 960404-48-2

Dapagliflozin is a sodium-glucose cotransporter subtype 2 (SGLT2) inhibitor that can be used in the treatment of diabetes mellitus type 2. It inhibits glucose reabsorption in the proximal tubule of the nephron and results in glycosuria, which helps to improve glycaemic control. Also, Dapagliflozin is used to lower the risk of sustained eGFR decline, end-stage renal disease, cardiovascular death, and hospitalization for heart failure in patients with chronic kidney disease who are at risk of progression.

Fórmula: C₂₁H₂₅ClO₆•C₃H₈O₂•H₂O

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 502.98 g/mol

Ref: 3D-BD300147