CAS 96574-01-5

Ácido salvianólico

Descrição:

Ácido salvianólico, com o número CAS 96574-01-5, é um composto polifenólico solúvel em água, derivado principalmente das raízes de Salvia miltiorrhiza, comumente conhecido como Danshen. Este composto é conhecido por suas potentes propriedades antioxidantes, que ajudam a eliminar radicais livres e reduzir o estresse oxidativo. Ácido salvianólico exibe vários efeitos farmacológicos, incluindo atividades anti-inflamatórias, cardioprotetoras e neuroprotetoras, tornando-o de interesse no campo da química medicinal. Sua estrutura apresenta múltiplos grupos hidroxila, contribuindo para sua alta reatividade e atividade biológica. Além disso, Ácido salvianólico tem sido estudado por seu papel potencial na melhoria da circulação sanguínea e proteção contra doenças cardiovasculares. O composto é frequentemente explorado na medicina tradicional e em aplicações terapêuticas modernas, destacando sua importância tanto nas práticas de saúde históricas quanto contemporâneas. Sua solubilidade em água aumenta sua biodisponibilidade, tornando-o um candidato adequado para várias formulações em medicina herbal e suplementos dietéticos.

Fórmula: C₂₆H₂₂O₁₀

InChI: InChI=1S/C26H22O10/c27-18-7-2-14(11-21(18)30)1-6-17-16(4-9-20(29)25(17)33)5-10-24(32)36-23(26(34)35)13-15-3-8-19(28)22(31)12-15/h1-12,23,27-31,33H,13H2,(H,34,35)/b6-1+,10-5+/t23-/m1/s1

Chave InChI: InChIKey=YMGFTDKNIWPMGF-UCPJVGPRSA-N

SMILES: C(=C/C1=CC(O)=C(O)C=C1)\C2=C(/C=C/C(O[C@H](CC3=CC(O)=C(O)C=C3)C(O)=O)=O)C=CC(O)=C2O

Sinónimos:

• (2R)-3-(3,4-Dihydroxyphenyl)-2-[(E)-3-[2-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]-3,4-dihydroxyphenyl]prop-2-enoyl]oxypropanoic acid
• (2R)-3-(3,4-dihydroxyphenyl)-2-{[(2E)-3-{2-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]-3,4-dihydroxyphenyl}prop-2-enoyl]oxy}propanoic acid
• (αR)-α-[[(2E)-3-[2-[(1E)-2-(3,4-Dihydroxyphenyl)ethenyl]-3,4-dihydroxyphenyl]-1-oxo-2-propen-1-yl]oxy]-3,4-dihydroxybenzenepropanoic acid
• 3-(3,4-dihydroxyphenyl)-2-{[(2E)-3-{2-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]-3,4-dihydroxyphenyl}prop-2-enoyl]oxy}propanoic acid
• Benzenepropanoic acid, α-[[(2E)-3-[2-[(1E)-2-(3,4-dihydroxyphenyl)ethenyl]-3,4-dihydroxyphenyl]-1-oxo-2-propen-1-yl]oxy]-3,4-dihydroxy-, (αR)-
• Benzenepropanoic acid, α-[[(2E)-3-[2-[(1E)-2-(3,4-dihydroxyphenyl)ethenyl]-3,4-dihydroxyphenyl]-1-oxo-2-propenyl]oxy]-3,4-dihydroxy-, (αR)-
• Benzenepropanoic acid, α-[[3-[2-[2-(3,4-dihydroxyphenyl)ethenyl]-3,4-dihydroxyphenyl]-1-oxo-2-propenyl]oxy]-3,4-dihydroxy-, [R-(E,E)]-
• Dan phenolic acid A
• Salvianolic acid
• (+)-Salvianolic acid A

(R)-3-(3,4-Dihydroxyphenyl)-2-(((E)-3-(2-((E)-3,4-dihydroxystyryl)-3,4-dihydroxyphenyl)acryloyl)oxy)propanoic acid

CAS: 96574-01-5

Fórmula: C₂₆H₂₂O₁₀

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 494.4469

Ref: IN-DA0039H9

Salvianolic acid A hydrate

CAS: 96574-01-5

Fórmula: C₂₆H₂₂O₁₀·xH₂O

Pureza: ≥ 98.0%

Cor e Forma: Yellow powder

Peso molecular: 494.45 (anhydrous)

Ref: 7W-GL2576

Salvianolic acid A

CAS: 96574-01-5

Salvianolic acid A

Pureza: ≥98%

Peso molecular: 494.45g/mol

Ref: 54-BUP13382

Salvianolic acid A

CAS: 96574-01-5

Salvianolic acid A has antioxidant, hepatoprotective, antithrombotic effect, and antiplatelet actions. it also has a significant protective effect against isoproterenol-induced myocardial infarction; it activates the Nrf2/HO-1 axis in RPE cells and protects against oxidative stress via activation of Akt/mTORC1 signaling. Salvianolic acid A (oral) can significantly improve glucose metabolism and inhibit oxidative injury as well as protect against impaired vascular responsiveness in STZ-induced diabetic rats. It is a novel matrix metalloproteinase-9 inhibitor, can prevents cardiac remodeling in spontaneously hypertensive rats.

Fórmula: C₂₆H₂₂O₁₀

Pureza: 95%~99%

Peso molecular: 494.452

Ref: BP-BP1247

Salvianolic acid A

CAS: 96574-01-5

Salvianolic acid A (Dan Phenolic Acid A) is an MMP-9 inhibitor. Salvianolic acid A has anti-inflammatory activity. Cost-effective and quality-assured.

Fórmula: C₂₆H₂₂O₁₀

Pureza: 99.08% - >99.99%

Cor e Forma: Yellow Solid

Peso molecular: 494.45

Ref: TM-T6S0444

Salvianolic acid a

CAS: 96574-01-5

Carboxylic acid with phenol function

Fórmula: C₂₆H₂₂O₁₀

Pureza: ≥ 90.0 % (HPLC)

Cor e Forma: Powder

Peso molecular: 494.46

Ref: 5G-80530

Salvianolic acid A

CAS: 96574-01-5

Salvianolic acid A is a polyphenolic compound, which is derived from the roots of the plant Salvia miltiorrhiza, commonly known as Danshen. It exerts its effects primarily through its potent antioxidant and anti-inflammatory activities. This compound operates by scavenging free radicals and inhibiting pro-inflammatory mediators, thus providing protection against oxidative stress and inflammation-related damage.

Fórmula: C₂₆H₂₂O₁₀

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 494.45 g/mol

Ref: 3D-FS73769

SALVIANOLIC ACID A

CAS: 96574-01-5

Pureza: 98%

Peso molecular: 494.4519958

Ref: 10-F859167

Salvianolic Acid A

Produto Controlado

CAS: 96574-01-5

Applications ISalvianolic acid A (Sal A) and salvianolic acid B (Sal B) were isolated and purified from the crude extract of Salvia miltiorrhiza. Antioxidant activities of Sal A and Sal B were also evaluated and the ABTS results showed that Sal A and Sal B exhibited high total antioxidant activities, their EC50 values were 1.35 0.00 and 1.43 0.01 .mu.g/mL.
References Lin, T., et al.: Biochem. Pharmacol., 51, 1237 (1996), Abd-Elazem, I., et al.: Antivir. Res., 55, 91 (2002), Ji, X., et al.: Life Sci., 73, 1413 (2003), Lin, Y., et al.: Biochem. Biophys. Res. Commun., 348, 593 (2006),

Fórmula: C₂₆H₂₂O₁₀

Cor e Forma: Light Yellow

Peso molecular: 494.45

Ref: TR-S100800

Salvianolic Acid A

CAS: 96574-01-5

Salvianolic Acid A

Peso molecular: 494.45g/mol

Ref: 54-BISN0136