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CAS 98796-51-1
:Timidina, 5'-O-[bis(4-metoxifenil)fenilmetil]-, 3'-[2-cianoetil N,N-bis(1-metiletil)fosforamidita]
Descrição:
Timidina, 5'-O-[bis(4-metoxifenil)fenilmetil]-, 3'-[2-cianoetil N,N-bis(1-metiletil)fosforamidita], comumente referido pelo seu número CAS 98796-51-1, é um derivado nucleosídico sintético usado principalmente no campo da biologia molecular e bioquímica. Este composto apresenta uma base de timidina, que é um componente do DNA, modificada nas posições 5' e 3'. A posição 5' é substituída por um grupo bis(4-metoxifenil)fenilmetilo, que melhora sua estabilidade e solubilidade, enquanto a posição 3' é modificada com um grupo de fosforamidito cianoetílico, que é crucial para seu papel na síntese de oligonucleotídeos. A presença do grupo fosforamidito permite a incorporação deste composto em cadeias de DNA durante a síntese em fase sólida, tornando-o valioso para a produção de oligonucleotídeos personalizados para aplicações de pesquisa e terapêuticas. Suas características estruturais contribuem para sua reatividade e utilidade em vários processos bioquímicos, particularmente na síntese de análogos de DNA e RNA.
Fórmula:C40H49N4O8P
InChI:InChI=1/C10H14N2O5.C3H6N2O2P/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8;1-3(2-4)7-8(5)6/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16);3H,5H2,1H3/q;-1/t6-,7+,8+;/m0./s1
Chave InChI:InChIKey=UNOTXUFIWPRZJX-CEXSRUIHSA-N
SMILES:C(OC[C@@H]1[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)C[C@@H](O1)N2C(=O)NC(=O)C(C)=C2)(C3=CC=C(OC)C=C3)(C4=CC=C(OC)C=C4)C5=CC=CC=C5
Sinónimos:- 5'-Dimethoxytrityl-3'-deoxythymidine 2'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
- 5'-O-(4,4'-Dimethoxytrityl)-thymidine-3'-cyanoethyl Phosphoramidite
- 5′-O-(4,4′-Dimethoxytrityl)thymidine 3′-(2-cyanoethyl-N,N-diisopropylphosphoramidite)
- 5′-O-(4,4′-Dimethoxytriyl)thymidine 3′-(2-cyanoethyl)-N,N-diisopropylphosphoramidite
- 5′-O-DMT-thymidine 3′-CE phosphoramidite
- DMT-dT phosphoramidite
- DNA T Phosphoramidite
- DT-CE phosphoramidite
- Deoxythymidine phosphoramidite
- Thymidine phosphoramidite
- Thymidine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
- Thymidine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3′-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]
- dT Phosphoramidite
- DMT-dT Amidite 1g, 60ml vial, 12 Pack
- DMT-dT amidite
- T-CE phosphoramidite
- 5'-DMT-dT phosphoramidite
- 5'-O-(4,4'-Dimethoxytrityl)thymidine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite
- thymidine-ce phosphoramidite for*biosearch 8000
- 3'-O-P-5'-O-DMT-2'-DEOXY-THYRIDINE [DT PHOSPHORAMIDITE]
- 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-thymidine 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]
- DMT-DT AMIDITE 1G AB 12 PACK
- 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-5-methyluridine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite
- 5'-O-DMT-2'-deoxythymidine-3'-CE Phosphoramidite
- DMT-dT Amidite 2g, 60ml vial, 12 Pack
- 5'-O-(4,4'-DIMETHOXYTRITYL)-2'-DEOXYTHYMIDINE-3'-(2-CYANOETHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE
- DMT-DT AMIDITE 2G 89 12 PACK
- REF DUPL: dT Phosphoramidite
- 5'-O-[Bis(4-Methoxyphenyl)phenylMethyl]-thyMidine 3'-[2-cyanoethyl N,N-bis(1-Methylethyl)phosphoraMidite]
- 5'-O-Dimethoxytrityl-2'-deoxy-thymidine-3'-O-(2-cyanoethyl)-Phosphoramidite
- N-blocked-5'-O-DMT 3'-CED thymidine phosphoramidite
- DMT-dT-CE-Phosphoramidite
- DMT-DT AMIDITE 10G SINGLE
- (2R,3S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl 2-cyanoethyl diisopropylphosphoramidite
- 5'-O-DMT-N2-isobutyryl-2'-de5'-O-DMT-Thymidine 3'-CE phosphoramidite
- DMT-dT Amidite 6.85g, 6 Pack
- 5'-O-DMT- 2'-Deoxy Thymidine Phosphoramidite
- DMT-DT AMIDITE 5G SINGLE
- DMT-DT AMIDITE 4G 60ML VIAL 12 PACK
- 5′-O-(4,4′-dimethoxytrityl)-2′-deoxythymidine-3′-O-[O-(2-cyanoethyl)-N,N′-diisopropylphosphoramidite]
- DMT-DT AMIDITE 2G AB 12 PACK
- DMT-dT Pharmadite
- Thymidine-3'-phosphoramidite
- DMT-DT AMIDITE 5G 6 PACK
- DMT-THYMIDINE CED PHOSPHORAMIDITE
- 5''-O-(4,4''-Dimethoxytrityl)-thymidine-3''-N,N-diisopropyl-(2-cyanoethyl)-pho
- DNAT-PHOSPHORAMIDITE
- 5'-O-(DIMETHOXYTRITYL)-THYMIDINE-3'-N,N-DIISOPROPYL(CYANOETHYL)PHOSPHORAMIDITE
- DMT-DT AMIDITE 20G 6 PACK
- Ver mais sinónimos
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9 produtos.
DMT-dT Phosphoramidite
CAS:Fórmula:C40H49N4O8PPureza:>98.0%(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:744.83T β-Cyanoethyl Phosphoramidite (5'-O-Dimethoxytritylthymidine-3'-O-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite)
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFórmula:C40H49N4O8PCor e Forma:White PowderPeso molecular:744.83Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3'-[2-cyanoethylbis(1-methylethyl)phosphoramidite]
CAS:Fórmula:C40H49N4O8PPureza:97%Cor e Forma:SolidPeso molecular:744.8128DMT-dT Phosphoramidite
CAS:DMT-dT Phosphoramidite is typically used in the synthesis of DNA.Fórmula:C40H49N4O8PCor e Forma:SolidPeso molecular:744.815'-O-DMT-thymidine 3'-CE phosphoramidite
CAS:<p>5'-O-DMT-thymidine 3'-CE phosphoramidite is a building block for the introduction of thymidine units into oligonucleotides. 5'-O-DMT-thymidine 3'-CE phosphoramidite is utilised in a broad range of applications, including the synthesis of natural and unnatural DNA and RNA strands. Phosphoramidites are the reagent class of choice for oligonucleotide synthesis as they contain readily removable orthogonal protecting groups and can be produced at reasonable scales. The diisopropylamino leaving group is readily cleaved upon exposure to an azole catalyst allowing for a highly efficient coupling reaction with a free hydroxyl group on the growing oligonucleotide and oxidation of the subsequent phosphite triester, followed by beta-elimination of the cyanoethyl group affords the stable phosphodiester linkage.</p>Fórmula:C40H49N4O8PPureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:744.83 g/mol
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