CAS: 99200-09-6 - Nebivolol

Fórmula: C₂₂H₂₅F₂NO₄

InChI: InChI=1S/C22H25F2NO4/c23-15-3-7-19-13(9-15)1-5-21(28-19)17(26)11-25-12-18(27)22-6-2-14-10-16(24)4-8-20(14)29-22/h3-4,7-10,17-18,21-22,25-27H,1-2,5-6,11-12H2

Chave InChI: InChIKey=KOHIRBRYDXPAMZ-UHFFFAOYSA-N

SMILES: FC1=CC=C2OC(CCC2=C1)C(O)CNCC(O)C3OC4=CC=C(F)C=C4CC3

Sinónimos:

• (iminobis(methylene))bis(6-fluoro-3,4-dihydro-
• 1-(6-Fluoro-chroman-2-yl)-2-[2-(6-fluoro-chroman-2-yl)-2-hydroxy-ethylamino]-ethanol
• 2,2'-iminobis[1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanol]
• 2H-1-Benzopyran-2-methanol, alpha,alpha'-
• 2H-1-Benzopyran-2-methanol, α,α′-[iminobis(methylene)]bis[6-fluoro-3,4-dihydro-
• 2H-1-benzopyran-2-methanol)
• Nebivolol-D4
• Nibivolol
• [2R*[R*[R*(S*)]]]-alpha,alpha'-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol
• alpha,alpha'-(Iminobis(methylene))bis(6-fluoro-3,4-dihydro-
• α,α′-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol]

(1R)-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-[[(2R)-2-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-hydroxyethyl]amino]ethanol

CAS: 99200-09-6

• Fórmula: C₂₂H₂₅F₂NO₄
• Pureza: 98%
• Cor e Forma: Solid
• Peso molecular: 405.4350

rac-Nebivolol (Mixture of Diastereomers)

CAS: 99200-09-6

• Fórmula: C₂₂H₂₅F₂NO₄
• Cor e Forma: White To Off-White Solid
• Peso molecular: 405.44

Nebivolol

CAS: 99200-09-6

Applications Nebivolol is a cardioselective beta-1 receptor blocking agent. References Montoya, A., et al.: Oncotarget, …

• Fórmula: C₂₂H₂₅F₂NO₄
• Cor e Forma: White To Off-White
• Peso molecular: 405.44

(Rac)-Nebivolol

CAS: 99200-09-6

(Rac)-Nebivolol, a racemic β1-adrenergic blocker (IC50=0.8 nM), has vasodilatory properties and mitigates ethanol-induced cardiac harm.

• Fórmula: C₂₂H₂₅F₂NO₄
• Cor e Forma: Liquid
• Peso molecular: 405.43