CAS 99290-97-8

(1Z,3R,4R,5S,6R,9R,10S,11S,12R,13R,15R)-10-[(2,6-Didesoxi-3-C-metil-3-O-metil-α-L-ribo-hexopiranosil)oxi]-6-etil-4,5-diidroxi-3,5,9,11,13,15-hexametil-12-[[3,4,6-tridesoxi-3-(dimetilamino)-β-D-xilo-hexopiranosil]oxi]-7,16-dioxa-2-azabiciclo[11.2.1]hexadec-1-en-8-ona

Descrição:

A substância química com o nome "(1Z,3R,4R,5S,6R,9R,10S,11S,12R,13R,15R)-10-[(2,6-Didesoxi-3-C-metil-3-O-metil-α-L-ribo-hexopiranosil)oxi]-6-etil-4,5-diidroxi-3,5,9,11,13,15-hexametil-12-[[3,4,6-tridesoxi-3-(dimetilamino)-β-D-xilo-hexopiranosil]oxi]-7,16-dioxa-2-azabiciclo[11.2.1]hexadec-1-en-8-ona" e número CAS "99290-97-8" é uma molécula orgânica complexa caracterizada por sua estereoquímica intrincada e múltiplos grupos funcionais. Apresenta uma estrutura bicíclica, que contribui para sua conformação tridimensional única. A presença de múltiplos grupos hidroxila indica potencial para ligações de hidrogênio, influenciando sua solubilidade e reatividade. A molécula também contém moieties de açúcar, sugerindo que pode exibir atividade biológica, possivelmente interagindo com enzimas ou receptores específicos. O grupo dimetilamino pode melhorar suas propriedades farmacológicas, afetando potencialmente sua interação com sistemas biológicos. No geral, a complexidade estrutural e a diversidade funcional deste composto o tornam um assunto de interesse em química medicinal e bioquímica, particularmente no contexto do desenvolvimento de medicamentos e aplicações terapêuticas.

Fórmula: C₃₇H₆₆N₂O₁₂

InChI: InChI=1S/C37H66N2O12/c1-14-25-37(10,44)29(41)22(6)38-32-18(2)16-36(9,51-32)31(50-34-27(40)24(39(11)12)15-19(3)46-34)20(4)28(21(5)33(43)48-25)49-26-17-35(8,45-13)30(42)23(7)47-26/h18-31,34,40-42,44H,14-17H2,1-13H3/b38-32-/t18-,19-,20+,21-,22-,23+,24+,25-,26+,27-,28+,29-,30+,31-,34+,35-,36-,37-/m1/s1

Chave InChI: InChIKey=BPENQAXMHXRNMD-ULJZSMOKSA-N

SMILES: O([C@H]1[C@]2(C)O/C(/[C@H](C)C2)=N\[C@H](C)[C@@H](O)[C@](C)(O)[C@@H](CC)OC(=O)[C@H](C)[C@@H](O[C@H]3C[C@](OC)(C)[C@@H](O)[C@H](C)O3)[C@@H]1C)[C@H]4[C@H](O)[C@@H](N(C)C)C[C@@H](C)O4

Sinónimos:

• (1Z,3R,4R,5S,6R,9R,10S,11S,12R,13R,15R)-10-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-6-ethyl-4,5-dihydroxy-3,5,9,11,13,15-hexamethyl-12-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-7,16-dioxa-2-azabicyclo[11.2.1]hexadec-1-en-8-one
• 7,16-Dioxa-2-azabicyclo[11.2.1]hexadec-1-en-8-one, 10-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-6-ethyl-4,5-dihydroxy-3,5,9,11,13,15-hexamethyl-12-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, [3R-(3R*,4R*,5S*,6R*,9R*,10S*,11S*,12R*,13R*,15R*)]-
• 7,16-Dioxa-2-azabicyclo[11.2.1]hexadec-1-en-8-one, 10-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-6-ethyl-4,5-dihydroxy-3,5,9,11,13,15-hexamethyl-12-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, (1Z,3R,4R,5S,6R,9R,10S,11S,12R,13R,15R)-

Erythromycin A (6,9-Imino Ether)

CAS: 99290-97-8

Fórmula: C₃₇H₆₆N₂O₁₂

Cor e Forma: White To Off-White Solid

Peso molecular: 730.94

Ref: 4Z-E-207

Erythromycin A 6,9-Imino Ether

CAS: 99290-97-8

Stability Hygroscopic
Applications An impurity in the synthesis of Erythromycin (E649950). An antibacterial.
References Zhang, L. et al.: J. Antibio., 64, 243 (2011); Koch, W.L., et al.: Anal. Profiles Drug Subs., 8, 157 (1979),

Fórmula: C₃₇H₆₆N₂O₁₂

Cor e Forma: White To Off-White

Peso molecular: 730.93

Ref: TR-E650015

Erythromycin A 6,9-imino ether

CAS: 99290-97-8

Erythromycin is a macrolide antibiotic that inhibits bacterial growth by binding to the 50S ribosomal subunit. It has been shown to have antibacterial activity against both staphylococci and streptococci. Erythromycin binds to the 23S ribosomal RNA, which prevents protein synthesis and cell division. The drug is used for the treatment of infections caused by bacteria susceptible to erythromycin, such as Group P2 (Streptococcus pneumoniae) and Group A (Staphylococcus aureus). Erythromycin also inhibits the biosynthesis of macrolactones, which are antibiotics related to erythromycin. These compounds are found in Streptomyces spp., Actinomycetes spp., and Mycobacterium smegmatis.

Fórmula: C₃₇H₆₆N₂O₁₂

Pureza: Min. 95%

Cor e Forma: White To Off-White Solid

Peso molecular: 730.93 g/mol

Ref: 3D-FE146285

Erythromycin A Imino ether

CAS: 99290-97-8

Fórmula: C₃₇H₆₆N₂O₁₂

Peso molecular: 730.94

Ref: ST-EA-CP-E18023