CAS: 99533-80-9 - protein kinase inhibitor from norcardiopsis sp.

Fórmula: C₂₇H₂₁N₃O₅

InChI: InChI=1S/C27H21N3O5/c1-26-27(33,25(32)34-2)11-18(35-26)29-16-9-5-3-7-13(16)20-21-15(12-28-24(21)31)19-14-8-4-6-10-17(14)30(26)23(19)22(20)29/h3-10,18,33H,11-12H2,1-2H3,(H,28,31)/t18-,26+,27+/m1/s1

Chave InChI: InChIKey=KOZFSFOOLUUIGY-SOLYNIJKSA-N

SMILES: O=C(OC)C1(O)CC2OC1(N3C=4C=CC=CC4C=5C3=C6C(C7=CC=CC=C7N62)=C8C(=O)NCC85)C

Sinónimos:

• (+)-K 252a
• 9,1-Epoxy-1H-diindolo(1,2,3-fg:3',2',1'-kl)pyrrolo(3,4-i)(1,6)benzodiazocine-10-carboxylic acid, 2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-, methyl ester, (9-alpha,10-beta,12-alpha)-
• 9,12-Epoxy-1H-diindolo(1,2,3-fg:3',2',1'-kl)pyrrolo(3,4-i)(1,6)benzodiazocine-10-carboxylic acid, 2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-, methyl ester, (9alpha,10beta,12alpha)-
• 9,12-Epoxy-1H-diindolo[1,2,3-fg:3′,2′,1′-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid, 2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-, methyl ester, (9S,10R,12R)-
• 9,12-Epoxy-1H-diindolo[1,2,3-fg:3′,2′,1′-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid, 2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-, methyl ester, [9S-(9α,10β,12α)]-
• Antibiotic K 252a
• Antibiotic SF 2370
• K 252
• K 252a Nocardiopsis sp.
• K252a
• Protein kinase inhibitor K252a
• Sf 2370
• methyl (5S,6R,8R)-6-hydroxy-5-methyl-13-oxo-5,6,7,8,14,15-hexahydro-13H-5,8-epoxy-4b,8a,14-triazadibenzo[b,h]cycloocta[1,2,3,4-jkl]cyclopenta[e]-as-indacene-6-carboxylate
• methyl (5S,8R)-6-hydroxy-5-methyl-13-oxo-5,6,7,8,14,15-hexahydro-13H-5,8-epoxy-4b,8a,14-triazadibenzo[b,h]cycloocta[1,2,3,4-jkl]cyclopenta[e]-as-indacene-6-carboxylate

K-252a

CAS: 99533-80-9

• Fórmula: C₂₇H₂₁N₃O₅
• Pureza: 100.0%
• Cor e Forma: Yellowish amorphous solid
• Peso molecular: 467.0

K-252a

CAS: 99533-80-9

• Fórmula: C₂₆H₂₁N₃O₅
• Pureza: 97%
• Cor e Forma: Solid
• Peso molecular: 455.4620

K-252a

CAS: 99533-80-9

K-252a, staurosporine analog, inhibits various kinases (PKC 470nM, PKA 140nM, CaMKII 270nM, PhK 1.7nM), from …

• Fórmula: C₂₇H₂₁N₃O₅
• Pureza: 98%
• Cor e Forma: Solid
• Peso molecular: 467.47

K-252a

CAS: 99533-80-9

• Fórmula: C₂₇H₂₁N₃O₅
• Pureza: ≥ 98.0%
• Cor e Forma: White to off-white powder
• Peso molecular: 467.47

K252a

CAS: 99533-80-9

• Fórmula: C₂₇H₂₁N₃O₅
• Pureza: By hplc: 99.23% (Typical Value in Batch COA)
• Cor e Forma: white powder
• Peso molecular: 467.47g/mol

K252a

CAS: 99533-80-9

• Fórmula: C₂₇H₂₁N₃O₅
• Peso molecular: 467.48

K-252A

CAS: 99533-80-9

K-252A is an antimicrobial agent that inhibits the growth of bacteria. It binds to the …

• Fórmula: C₂₇H₂₁N₃O₅
• Pureza: Min. 95%
• Peso molecular: 467.49 g/mol

K252a

CAS: 99533-80-9

Applications K252a is a protein kinase inhibitor. It is an analogue of staurosporine (S685000). It …

• Fórmula: C₂₇H₂₁N₃O₅
• Cor e Forma: Neat
• Peso molecular: 467.47

K252a

CAS: 99533-80-9

Inhibitor of TRK family of kinases

• Fórmula: C₂₇H₂₁N₃O₅
• Pureza: Min. 95%
• Peso molecular: 467.47 g/mol