Aminoácidos com Grupos Protectores

Versatile small molecule scaffold

N-Fmoc-L-homoserine is a carbohydrate molecule that has been synthesised using solid-phase methodology. It is glycosylated and glycolic, with a carboxy chain. N-Fmoc-L-homoserine is expressed in E. coli cells and purified by acetylation. This compound has been synthesised as part of the carbohydrate antigens project, which aims to produce synthetic glycan structures for use as vaccine adjuvants.

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Fmoc-N-(propargyl)-glycine (Fmoc-PG) is a synthesized and modified amino acid that can be used in the treatment of cancer. Fmoc-PG has been shown to inhibit the growth of tumor cells when conjugated with positron emission radiotracers, such as 18F-Fluorodeoxyglucose, for use in positron emission tomography. Fmoc-PG also inhibits the glucose analogue, which may lead to an improvement of neurological function. Fmoc-PG has been shown to be metabolized by acid conjugates and conjugates, resulting in increased stability and reduced toxicity.

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Please enquire for more information about Fmoc-[D10]Leu-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>Versatile small molecule scaffold</p>

<p>Please enquire for more information about Fmoc-Val-Cit-PAB-MMAE including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Versatile small molecule scaffold</p>

Please enquire for more information about rac Fmoc-trifluoromethylalanine including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Fmoc-Glu-OH is a carboxylate that is used in the synthesis of acidic, disulfide bond containing, conjugates. It has been shown to be an effective anticancer agent against MDA-MB-231 cells and other cancer cells. Fmoc-Glu-OH is an antimicrobial agent that inhibits the growth of bacteria by targeting intracellular targets. This drug also binds to bacterial 16S ribosomal RNA and prevents protein synthesis, leading to cell death in the target organism.

<p>Fmoc-PEG4-NHS ester is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Fmoc-PEG4-NHS ester is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>Please enquire for more information about Fmoc-O-sulfo-L-tyrosine sodium salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

Fmoc-D-Hyp(tBu)-OH is a carbonyl compound that belongs to the class of glycopeptide. It has been shown to have anti-cancer activity against thp-1 cells, which are derived from human acute promyelocytic leukemia cells. Fmoc-D-Hyp(tBu)-OH inhibits cell proliferation and induces apoptosis in thp-1 cells. This chemical has also been shown to inhibit the production of collagen, an important component of blood vessel walls, by inhibiting the activity of lysyl hydroxylase. The biological function of this drug is not fully understood but it may be related to autophagy and asymmetric synthesis.