
EGFR
Os inibidores do receptor do fator de crescimento epidérmico (EGFR) são compostos que bloqueiam a sinalização do EGFR, um receptor frequentemente superexpresso em vários tipos de câncer e que desempenha um papel crucial na angiogênese. Os inibidores de EGFR são usados para prevenir o crescimento e a metástase de tumores, interrompendo as vias que promovem a formação de vasos sanguíneos nos tumores. Esses inibidores são amplamente utilizados na pesquisa e terapia do câncer. Na CymitQuimica, oferecemos uma seleção diversificada de inibidores de EGFR de alta qualidade para apoiar sua pesquisa em oncologia e angiogênese.
Foram encontrados 572 produtos de "EGFR"
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Petosemtamab
CAS:<p>Petosemtamab (MCLA 158), a dual-action monoclonal antibody targets EGFR & LGR5, used in solid tumor research like HNSCC & CRC.</p>Pureza:> 95% - > 95%Cor e Forma:LiquidPeso molecular:145.97 kDaLapatinib Ditosylate
CAS:<p>Lapatinib Ditosylate (Tykerb ditosylate) is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2).</p>Fórmula:C29H26ClFN4O4S·2C7H8O3SPureza:99.41%Cor e Forma:Yellow SolidPeso molecular:925.46Erlotinib hydrochloride
CAS:<p>Erlotinib hydrochloride (NSC 718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.</p>Fórmula:C22H23N3O4·HClPureza:99.78% - 99.85%Cor e Forma:White Or Off-White PowderPeso molecular:429.9LCH-7749944
CAS:<p>LCH-7749944 suppresses human gastric cancer cell growth, induces apoptosis, and inhibits PAK4 with IC50 of 14.93 μM.</p>Fórmula:C20H22N4O2Pureza:99.48%Cor e Forma:SolidPeso molecular:350.41Gancotamab
CAS:<p>Gancotamab (MM-302) is a polyethylene glycolated liposome targeting HER2 with antitumor activity for the study of advanced HER2-positive breast cancer.</p>Pureza:96.7% (SDS-PAGE); 98.4% (SEC-HPLC) - 96.7% (SDS-PAGE); 98.4% (SEC-HPLC)Cor e Forma:Liquid(2E)-2-Cyano-3-(3,4-dihydroxyphenyl)-N-[(1S)-1-phenylethyl]-2-propenamide
CAS:Fórmula:C18H16N2O3Pureza:97%Cor e Forma:SolidPeso molecular:308.3312Mutated EGFR-IN-1
CAS:<p>Mutated EGFR-IN-1 (Osimertinib analog) is a useful intermediate for the inhibitors design for mutated EGFR, such as L858R EGFR, Exonl9 deletion activating</p>Fórmula:C25H31N7OPureza:98.91%Cor e Forma:SolidPeso molecular:445.56Panitumumab
CAS:<p>Panitumumab is a fully human IgG2 monoclonal antibody targeting the epidermal growth factor receptor EGFR).</p>Pureza:95% - 98.1% (SDS-PAGE); 99.4% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:147 kDaMargetuximab
CAS:<p>Margetuximab (MGAH-22) is a second generation anti-HER2 monoclonal antibody with anti-tumor activity.</p>Pureza:95.3% (SDS-PAGE); 99.3% (SEC-HPLC) - 95.3% (SDS-PAGE); 99.3% (SEC-HPLC)Cor e Forma:Liquid2-ButynaMide, N-[4-[(3-broMophenyl)aMino]-6-quinazolinyl]-
CAS:Fórmula:C18H13BrN4OPureza:97%Cor e Forma:SolidPeso molecular:381.22601-[4-[4-[[2-[(1E)-2-[4-(Trifluoromethyl)phenyl]ethenyl]-4-oxazolyl]methoxy]phenyl]butyl]-1H-1,2,3-triazole
CAS:Fórmula:C25H23F3N4O2Pureza:98%Cor e Forma:SolidPeso molecular:468.4709Propanedinitrile,2-[(4-methoxyphenyl)methylene]-
CAS:Fórmula:C11H8N2OPureza:98%Cor e Forma:SolidPeso molecular:184.1940Intetumumab
CAS:<p>Intetumumab (CNTO 95) is a fully humanized anti-α(v)-integrin monoclonal antibody that is a radiosensitizer for xenograft tumor-bearing mice.</p>Pureza:97.6% (SDS-PAGE); 97.1% (SEC-HPLC) - 97.6% (SDS-PAGE); 97.1% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:145.6 (kDa)Barecetamab
CAS:<p>Barecetamab (ISU-104) is a humanized monoclonal antibody against tyrosine protein kinase ErbB3 with anticancer activity.</p>Pureza:97.1% (SDS-PAGE); 96.4% (SEC-HPLC) - 97.1% (SDS-PAGE); 96.4% (SEC-HPLC)Cor e Forma:LiquidErlotinib
CAS:<p>Erlotinib (NSC-718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.</p>Fórmula:C22H23N3O4Pureza:98.19% - 99.98%Cor e Forma:White To Off-White PowderPeso molecular:393.44Pyrotinib dimaleate
CAS:<p>Pyrotinib dimaleate is a selective EGFR/HER2 dual inhibitor, respectively, for the treatment of HER2-positive breast cancer.Cost-effective and quality-assured.</p>Fórmula:C40H39ClN6O11Pureza:97.27% - 99.52%Cor e Forma:SolidPeso molecular:815.22


