Serina/treonina quinase
Gli inibitori delle chinasi serina/treonina sono composti che prendono di mira gli enzimi responsabili della fosforilazione dei residui di serina e treonina sulle proteine, i quali svolgono un ruolo cruciale nella regolazione dell'apoptosi e di altri processi cellulari. Queste chinasi sono coinvolte in vie di segnalazione che controllano la crescita, la divisione e la morte cellulare programmata. Inibire specifiche chinasi serina/treonina può alterare l'equilibrio tra sopravvivenza cellulare e apoptosi, rendendo questi inibitori strumenti essenziali nella ricerca sul cancro e in altre aree della biologia cellulare. Presso CymitQuimica, offriamo una selezione completa di inibitori delle chinasi serina/treonina di alta qualità per supportare la tua ricerca in apoptosi, trasduzione del segnale e meccanismi delle malattie.
Foram encontrados 18 produtos de "Serina/treonina quinase"
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BMT-124110 Formate
BMT-124110 Formate is a selective AAK1 inhibitor (IC50: 0.9 nM) with anti-injury sensory activity.BMT-124110 Formate inhibits the BMP-2-inducible protein kinase
Fórmula:C22H20N2O2Pureza:99.52%Cor e Forma:SoildPeso molecular:344.41CRA-2059
CAS:CRA-2059 is a selective and reversible inhibitor of human tryptase beta, exhibiting a Ki value of 620 pM against recombinant human tryptase beta (rHTβ).Fórmula:C34H46N12O8Pureza:97.68% - 99.29%Cor e Forma:SolidPeso molecular:750.82TLK1-IN-1
TLK1-IN-1 (Compound 5n) is a TLK1 inhibitor with an IC50 of 7.2 μM for TLK1B and a GI50 of 2.7 μM for LNCaP cells. It induces DNA damage and apoptosis (Apoptosis) in cancer cells and is applicable in prostate cancer research.Fórmula:C24H23BrClN5O3Cor e Forma:SoildPeso molecular:544.831,8-Diazanaphthalene
CAS:1,8-Diazanaphthalene inhibits Protein Kinase B with a binding constant Ka=407 μM.Fórmula:C8H6N2Peso molecular:130.15PKD-IN-1
CAS:CRT0066101 is an inhibitor of PKD.Fórmula:C18H19ClN4OPureza:98%Cor e Forma:SolidPeso molecular:342.82GAK inhibitor 49
CAS:GAK inhibitor 49 is a highly selective and ATP-competitive cyclin G associated kinase (GAK) inhibitor (IC50: 56 nM; Ki: 0.54 nM ).Fórmula:C20H22N2O5Pureza:98.71%Cor e Forma:SolidPeso molecular:370.4Ref: TM-T8535
1mg54,00€5mg111,00€10mg177,00€25mg299,00€50mg430,00€100mg587,00€200mg792,00€1mL*10mM (DMSO)128,00€CID755673
CAS:CID755673 inhibits PKD (IC50: 182 nM), with selectivity over PLK1, AKT, CAMKIIα, CAK, PKC.Fórmula:C12H11NO3Pureza:97.68% - 99.84%Cor e Forma:SolidPeso molecular:217.221-Naphthyl PP1
CAS:1-Naphthyl PP1 (1-NA-PP 1) is a selective src inhibitor(v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively)Fórmula:C19H19N5Pureza:99.85%Cor e Forma:White Cyrstalline SolidPeso molecular:317.39kb NB 142-70
CAS:kb NB 142-70 is a selective protein kinase D (PKD) inhibitor (IC50 values are 28.3, 58.7 and 53.2 nM for PKD1, 2 and 3 respectively).Fórmula:C11H9NO2S2Pureza:98.15% - ≥95%Cor e Forma:SolidPeso molecular:251.32SGC-GAK-1
CAS:SGC-GAK-1 is a selective cyclin G-associated kinase (GAK) inhibitor (Ki: 3.1 nM).
Fórmula:C18H17BrN2O3Pureza:99.85%Cor e Forma:SolidPeso molecular:389.24MLCK inhibitor peptide 18 acetate
MLCK inhibitor peptide 18 acetate: Selective (IC50=50nM), 4000x more than CaM kinase II. Does not block PKA. Cell-permeable.Fórmula:C62H109N23O13Pureza:99.57%Cor e Forma:SolidPeso molecular:1384.67SRPIN340
CAS:SRPIN340 (SRPK inhibitor), a serine/arginine-rich protein kinase (SRPK)-specific inhibitor, is potent for SRPK1 (IC50 = 0.89 uM).Fórmula:C18H18F3N3OPureza:99.79% - 99.96%Cor e Forma:SolidPeso molecular:349.35Ref: TM-T1954
2mg44,00€5mg65,00€10mg100,00€25mg177,00€50mg324,00€100mg421,00€500mg945,00€1mL*10mM (DMSO)71,00€N-Cyclohexyl-4-[1-(1-piperazinyl)-2,6-naphthyridin-3-yl]-2-pyridinamine
CAS:Novel 2,6-naphthyridine inhibits PKC/PKD, identified by HTS.Fórmula:C23H28N6Pureza:98.35%Cor e Forma:SolidPeso molecular:388.51CID 2011756
CAS:CID 2011756 is an ATP-competitive and specific PKD1 inhibitor.Fórmula:C22H21ClN2O3Pureza:98.15% - ≥95%Cor e Forma:SolidPeso molecular:396.87SPHINX31
CAS:SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1; IC50: 5.9 nM).Fórmula:C27H24F3N5O2Pureza:99.3% - 99.87%Cor e Forma:SolidPeso molecular:507.51Ref: TM-T5194
1mg40,00€5mg84,00€10mg97,00€25mg180,00€50mg269,00€100mg430,00€500mg998,00€1mL*10mM (DMSO)87,00€SRPKIN-1
CAS:SRPKIN-1 is a covalent and irreversible inhibitor of SRPK1/2 (IC50s: 35.6 and 98 nM, respectively).Fórmula:C27H21FN2O3SPureza:98%Cor e Forma:SolidPeso molecular:472.53Anti-neuroinflammation agent 3
CAS:Compound A.10.3 (Anti-neuroinflammation agent 3) exhibits inhibitory activity against various Ser/Thr kinases or receptor/non-receptor tyrosine kinases.Fórmula:C22H23FN6O2Peso molecular:422.455Protein kinase inhibitor 14
CAS:Protein kinase inhibitor 14 (Compound 13) exhibits inhibitory effects on various serine/threonine kinases and receptor/non-receptor tyrosine kinases.Fórmula:C22H22F2N6OCor e Forma:SolidPeso molecular:424.447
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