TNF
Gli inibitori del fattore di necrosi tumorale (TNF) sono composti che bloccano l'attività del TNF, una citochina coinvolta nell'infiammazione e nella regolazione dell'apoptosi. Il TNF può indurre l'apoptosi in alcuni tipi di cellule mentre promuove la sopravvivenza e l'infiammazione in altri. L'inibizione del TNF è cruciale nel trattamento delle malattie autoimmuni, delle condizioni infiammatorie croniche e di alcuni tipi di cancro. Gli inibitori del TNF aiutano a modulare la risposta immunitaria e a ridurre i danni ai tessuti causati da un'infiammazione eccessiva. Presso CymitQuimica, offriamo una vasta gamma di inibitori del TNF di alta qualità per supportare la tua ricerca in immunologia, infiammazione e apoptosi.
Foram encontrados 144 produtos para "TNF".
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Ispectamab
Ispectamab is an anti-TNFRSF17 human monoclonal antibody for research on TNFRSF17-associated biology.Peso molecular:~148 kDaAsunercept
CAS:Asunercept (APG101/CAN008) is a CD95-Fc protein targeting CD95L, used in GBM, MDS, and GvHD research.Cor e Forma:LiquidAnti-Mouse TNF α Antibody (TN3-19.12)
Anti-Mouse TNF alpha Antibody is a rat-derived IgG inhibitor targeting mouse TNF alpha.Pureza:95%Cor e Forma:LiquidPeso molecular:~150 kDaOnfekafusp alfa
CAS:Onfekafusp alfa (L19TNF), a trimeric fusion of L19 scFv and human TNF, targets malignant glioma.Cor e Forma:LiquidKGYY15
CAS:KGYY15 (Mouse KGYY15), a peptide that targets CD40, exhibits weak inhibition of the CD40-CD40L interaction, with an IC50 exceeding 1 mM. At a concentration of 100 μM, KGYY15 activates the NF-κB pathway by 33%.Fórmula:C84H129N21O22SCor e Forma:SolidPeso molecular:1817.12Zigakibart
CAS:Zigakibart (BION-1301) is a humanized monoclonal antibody targeting TNFSF13 with anti-inflammatory activity for the study of immunoglobulin A nephropathy (IgAN)Pureza:95.8% (SDS-PAGE); 99.8% (SEC-HPLC) - 95.8% (SDS-PAGE); 99.8% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:145.03 kDa (Predicted)Lenercept
CAS:Lenercept (Ro 45-2081) is a recombinant fusion protein combining the soluble TNF-receptor (p55) with the Fc portion of human IgG1 [1].Cor e Forma:LiquidTNF-α-IN-9
CAS:TNF-α-IN-9 is an NDM-1 inhibitor-3 analog and is a TNF-α inhibitor.TNF-α-IN-9 shows low inhibitory activity.Fórmula:C17H14O4Pureza:99.21%Cor e Forma:SolidPeso molecular:282.2907Giloralimab
CAS:Giloralimab (ABBV-927) is a antibody targeting CD40 with anticancer activity for the study of triple-negative breast cancer and non-small cell lung cancer.Pureza:95.6% (SDS-PAGE); 95.1% (SEC-HPLC) - 95.6% (SDS-PAGE); 95.1% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:146.34 kDa (Predicted)Sotigalimab
CAS:Sotigalimab (APX 005) is a monoclonal antibody targeting CD40 with anticancer activity for the study of metastatic pancreatic cancer.Pureza:98.50% - 98.50%Cor e Forma:LiquidPeso molecular:144.35 kDa (Predicted)Nerelimomab
CAS:Nerelimomab (BAYX1351), an anti-TNF-α antibody, is utilized in sepsis research [1] [2].Cor e Forma:LiquidTilogotamab
CAS:Tilogotamab (GEN-1029) is an agonistic hexameric complex targeting two independent epitopes on DR5, used for studying multiple myeloma (MM).Pureza:95%Cor e Forma:LiquidPeso molecular:144.88 kDa (Predicted)Tengonermin
CAS:Tengonermin (ARENEGYR), a vascular agent, is TNF-α fused with CNGRCG peptide, enhancing chemo and T-cell access in tumors.Cor e Forma:LiquidPovetacicept
CAS:Povetacicept (ALPN-303) is an engineered fusion protein that incorporates the TACI domain and functions as a dual antagonist of APRIL/BAFF. It modulates B lymphocytes and pathogenic autoantibodies and is being researched for its potential application in treating lupus and other autoimmune diseases associated with B cells.Tanfanercept
CAS:Tanfanercept (HL036337) is an anti-TNF-α antibody, improving corneal erosions in dry eye mice.Cor e Forma:LiquidRanevetmab
CAS:Ranevetmab (NV-01), a caninized anti-NGF mAb, relieves pain in DJD research.Cor e Forma:LiquidAnti-Mouse 4-1BBL/CD137L Antibody (TKS-1)
Anti-Mouse 4-1BBL/CD137L Antibody (TKS-1) inhibits T cell activity, used in cancer, infection, inflammation and immunology.Pureza:95% - 99.2% (SDS-PAGE); 100.0% (SEC-HPLC)Peso molecular:143.08 kDa (Predicted)Varlilumab
CAS:Varlilumab (CDX-1127) is a novel human IgG1 anti-CD27 monoclonal antibody. Varlilumab has antitumor activity and can be used to study advanced solid tumors.Pureza:SDS-PAGE:95% SEC-HPLC:98.65%Cor e Forma:Transparent LiquidPeso molecular:146 kDa (Predicted)TNF-α Antagonist
CAS:TNF-α antagonist is an exocyclic peptide that mimics the critical TNF-α recognition loop on TNF receptor I complex and, thus, prevents ligand interaction withFórmula:C58H71N11O15S2Cor e Forma:SolidPeso molecular:1226.39Adalimumab β
CAS:Adalimumab beta (ABP-501) is an anti-TNF-α monoclonal antibody utilized in the study of rheumatoid arthritis (RA) [1].Cor e Forma:Liquid
