p53
Os inibidores de p53 têm como alvo a proteína p53, um supressor tumoral que desempenha um papel crucial na regulação do ciclo celular, reparo de DNA e apoptose. Embora o p53 seja frequentemente mutado ou inativado em células cancerígenas, sua inibição às vezes é necessária para proteger as células saudáveis da apoptose durante certos tratamentos. Por outro lado, restaurar a função do p53 em tumores pode levar à apoptose das células cancerígenas. A pesquisa sobre inibidores de p53 é complexa e significativa para compreender os mecanismos do câncer e desenvolver novas terapias. Na CymitQuimica, oferecemos uma seleção de inibidores e moduladores de p53 de alta qualidade para apoiar sua pesquisa em biologia do câncer, apoptose e desenvolvimento terapêutico.
Foram encontrados 64 produtos para "p53".
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Anti-p53 Antibody (9G129)
Anti-p53 Antibody (9G129) is a Rabbit antibody targeting p53. Anti-p53 Antibody (9G129) can be used in IHC-P,ICC/IF.Cor e Forma:Odour LiquidHLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled
p53 is a tumor suppressor protein.Cor e Forma:Odour Lyophilized PowderHLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Tetramer Protein, Human, MHC (His & Avi)
p53 is a tumor suppressor protein.Cor e Forma:Lyophilized PowderPeso molecular:The protein has a predicted MW of 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reducing (N) condition based on Tris-Bis PAGE result.HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Monomer Protein, Human, MHC (His & Avi)
p53 is a tumor suppressor protein.Cor e Forma:Lyophilized PowderPeso molecular:The protein has a predicted MW of 50.5 kDa. Due to glycosylation, the protein migrates to 51-60 kDa based on Tris-Bis PAGE result.Anti-p53 Antibody (9D896)
Anti-p53 Antibody (9D896) is an antibody targeting p53. Anti-p53 Antibody (9D896) can be used in ELISA, WB, IHC, IF.Cor e Forma:Odour LiquidHLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Monomer Protein, Human, MHC (His & Avi), Biotinylated
p53 is a tumor suppressor protein.Cor e Forma:Lyophilized PowderPeso molecular:The protein has a predicted MW of 50.5 kDa. Due to glycosylation, the protein migrates to 51-60 kDa based on Tris-Bis PAGE result.HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled
p53 is a tumor suppressor protein.Cor e Forma:Odour Lyophilized PowderAnti-p53 Antibody (3K688)
Anti-p53 Antibody (3K688) is a Rabbit antibody targeting p53. Anti-p53 Antibody (3K688) can be used in WB,ELISA,IP.Cor e Forma:Odour LiquidHLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Tetramer Protein, Human, MHC (His & Avi)
p53 is a tumor suppressor protein.Cor e Forma:Lyophilized PowderPeso molecular:The protein has a predicted MW of 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reducing (N) condition based on Tris-Bis PAGE result.Methylstat
CAS:Methylstat is a methyl ester prodrug of a Jumonji C domain-containing histone demethylase (JMJD) inhibitor that has favorable cell permeability.Fórmula:C28H31N3O6Pureza:98.34% - 98.34%Cor e Forma:White SolidPeso molecular:505.5622p53 Protein, Cynomolgus, Recombinant
p53, also known as Tp53, is a DNA-binding protein which belongs to the p53 family.Cor e Forma:Lyophilized PowderPeso molecular:43.7 kDa (predicted); 48 kDa (reducing conditions)HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Monomer Protein, Human, MHC (His & Avi), Biotinylated
p53 is a tumor suppressor protein.Cor e Forma:Lyophilized PowderPeso molecular:The protein has a predicted MW of 50.5 kDa. Due to glycosylation, the protein migrates to 55-60 kDa based on Tris-Bis PAGE result.Anti-Phospho-TP53 (Ser392) Antibody (7W136)
Anti-Phospho-TP53 (Ser392) Antibody (7W136) is an antibody targeting Phospho-TP53 (Ser392). Anti-Phospho-TP53 (Ser392) Antibody (7W136) can be used in ELISA, WB.Cor e Forma:Odour LiquidAnti-p53 Antibody (1J151)
Anti-p53 Antibody (1J151) is a Mouse antibody targeting p53. Anti-p53 Antibody (1J151) can be used in ELISA(Cap).Cor e Forma:Odour LiquidKCC-07
CAS:KCC-07: Selective, potent, brain-penetrant MBD2 inhibitor with anticancer effects, blocking MBD2-DNA binding and activating BAI1 signaling.Fórmula:C14H11N3OSPureza:98.86% - 99.01%Cor e Forma:SolidPeso molecular:269.322YK-3-237
CAS:YK-3-237 (B-[2-Methoxy-5-[(1E)-3-oxo-3-(3,4,5-trimethoxyphenyl)-1-propen-1-yl]phenyl]boronic acid) reduces acetylation of mtp53 and exhibits anti-proliferativeFórmula:C19H21BO7Pureza:99.47%Cor e Forma:SolidPeso molecular:372.18Nutlin-3a
CAS:Nutlin-3a is the active enantiomer of Nutlin-3, an MDM2 antagonist that inhibits MDM2-p53 interaction. Nutlin-3a has antitumor activity. Cost-effective and quality-assured.Fórmula:C30H30Cl2N4O4Pureza:95.62% - 99.71%Cor e Forma:SolidPeso molecular:581.49Theaflavin 3,3′-digallate
CAS:Theaflavin 3,3'-digallate, a major polyphenol found in black tea, is an inducer of oxidative stress which has anti-inflammatory and cancerFórmula:C43H32O20Pureza:98.71% - 99.86%Cor e Forma:SolidPeso molecular:868.7022NSC348884
CAS:NSC348884, a nucleophosmin inhibitor, disrupts oligomers, induces apoptosis, and inhibits cancer cell growth (IC50: 1.7-4.0 μM).Fórmula:C38H40N10Pureza:98.69% - 99.91%Cor e Forma:SolidPeso molecular:636.7912NSC-87877 disodium
CAS:NSC-87877 disodium (NSC87877) is a cell-permeable inhibitor of both SHP-1 and SHP-2. NSC-87877 also inhibits EGF-induced Erk1/2 activation in HEK293 cells.Fórmula:C19H11N3Na2O7S2Pureza:97.89%Cor e Forma:SolidPeso molecular:503.416
