Cinesina
Os inibidores de cinesina têm como alvo as proteínas motoras cinesinas, que são responsáveis pelo transporte de carga celular ao longo dos microtúbulos e desempenham um papel crucial na divisão celular, particularmente durante a mitose. As cinesinas estão envolvidas no movimento de cromossomos e outras organelas durante a divisão celular. Inibir as cinesinas pode interromper esses processos, levando à parada do ciclo celular e possível morte celular, tornando esses inibidores valiosos na pesquisa do câncer. Na CymitQuimica, oferecemos uma gama diversificada de inibidores de cinesina de alta qualidade para apoiar sua pesquisa em biologia celular, mitose e terapia do câncer.
Foram encontrados 67 produtos de "Cinesina"
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UMK57
CAS:<p>UMK57 is a CENP-Ei and MCAK enhancer, selectively promoting k-MT attachment error correction to inhibit chromosome missegregation of small molecule compounds,</p>Fórmula:C17H17N3SPureza:99.81%Cor e Forma:SolidPeso molecular:295.4KSP-IA
CAS:<p>KSP-IA is a potent, specific, allosteric, and cell-active KSP inhibitor.</p>Fórmula:C21H22F2N2OPureza:98%Cor e Forma:SolidPeso molecular:356.41Luvixasertib hydrochloride
CAS:<p>CFI-402257 hydrochloride, a highly selective and orally bioavailable inhibitor targeting TTK/Mps1, demonstrates an in vitro IC50 value of 1.7 nM against TTK. This compound exhibits anti-cancer activity [1].</p>Fórmula:C28H31ClN6O3Cor e Forma:SolidPeso molecular:535.04MC-Val-Cit-PAB-Ispinesib
CAS:<p>MC-Val-Cit-PAB-Ispinesib (Compound 509) is a potent Eg5 inhibitor and a click chemistry reagent [1].</p>Fórmula:C59H71ClN10O10Cor e Forma:SolidPeso molecular:1115.71CCT251455
CAS:<p>CCT251455, the mitotic kinase monopolar spindle 1 (MPS1/TTK) inhibitor, is a potent (IC50=3 nM) and specific chemical tool.</p>Fórmula:C26H26ClN7O2Pureza:99.1% - 99.1%Cor e Forma:SolidPeso molecular:503.98Kif15-IN-2
CAS:<p>Kif15-IN-2 is a kinesin Kif15 inhibitor with potential anticancer activity and can be used in prostate cancer research.</p>Fórmula:C20H20N6O4SPureza:98.17%Cor e Forma:SolidPeso molecular:440.48NTRC 0066-0
CAS:<p>NTRC 0066-0 is a TTK inhibitor that can be used in cancer research.</p>Fórmula:C33H39N7O2Pureza:98.30%Cor e Forma:SolidPeso molecular:565.71Litronesib
CAS:<p>Litronesib is a selective inhibitor of mitosis-specific kinesin Eg5. It also has antitumor activity.</p>Fórmula:C23H37N5O4S2Pureza:98%Cor e Forma:SolidPeso molecular:511.7PVZB1194
CAS:<p>PVZB1194, a biphenyl-type inhibitor of Kinesin spindle protein Eg5 (KIF11), exhibits anticancer potential by inducing cell cycle arrest and apoptosis through</p>Fórmula:C13H9F4NO2SPureza:98%Cor e Forma:SolidPeso molecular:319.28SB-743921 free base
CAS:<p>SB-743921, a kinesin spindle protein (KSP) inhibitor, is used potentially for the treatment of non-Hodgkin's lymphoma (NHL).</p>Fórmula:C31H33ClN2O3Pureza:98%Cor e Forma:SolidPeso molecular:517.06CCT-271850
CAS:<p>CCT-271850 is an inhibitor of the spindle checkpoint function of Monospindle 1.</p>Fórmula:C24H29N7OPureza:98%Cor e Forma:SolidPeso molecular:431.53CFI-402257
CAS:<p>CFI-402257 is a selective inhibitor of Mps1/TTK kinase (Mps1 Ki = 0.09 nM; EC50 = 6.5 nM)and can be used in studies about hepatocellular carcinoma diseases.</p>Fórmula:C28H30N6O3Pureza:96.66% - 99.51%Cor e Forma:SolidPeso molecular:498.58Mps1-IN-8
CAS:<p>Mps1-IN-8, a Mps1 inhibitor, can be utilized in the study of various tumors [1].</p>Fórmula:C35H47N8O6PCor e Forma:SolidPeso molecular:706.77RMS-07
CAS:<p>RMS-07, a covalent MPS1/TTK inhibitor, has an IC50 of 13.1 nM, targeting a kinase hinge cysteine.</p>Fórmula:C35H40N8O2Cor e Forma:SolidPeso molecular:604.74MKLP2-IN-1
CAS:<p>MKLP2-IN-1 (compound 12a) is an inhibitor of MKLP2 that demonstrates excellent oral bioactivity. In vitro, MKLP2-IN-1 inhibits the ATPase activity stimulated by recombinant MKLP2 microtubules and, in a mouse Calu-6 lung cancer model, it effectively suppresses tumor growth.</p>Fórmula:C23H19BrFN3O2Cor e Forma:SolidPeso molecular:468.318Terpendole E
CAS:<p>Terpendole E is an atypical L5 site inhibitor.</p>Fórmula:C28H39NO3Cor e Forma:SolidPeso molecular:437.61Kolavenic acid analog
CAS:<p>KAA, an anticancer compound, inhibits centrosome clustering and targets HSET+ yeast and cancer cells.</p>Fórmula:C25H38O4Cor e Forma:SolidPeso molecular:402.57
