Integrinas
Os inibidores de integrinas têm como alvo as integrinas, uma família de receptores de superfície celular que desempenham um papel crucial na adesão celular, migração e transdução de sinais. As integrinas estão envolvidas na regulação do ciclo celular, particularmente em processos como divisão e diferenciação celular. Inibir integrinas pode interromper esses processos, levando à parada do ciclo celular e apoptose, tornando esses inibidores valiosos na pesquisa do câncer e no estudo da metástase. Na CymitQuimica, oferecemos uma ampla gama de inibidores de integrinas de alta qualidade para apoiar sua pesquisa em regulação do ciclo celular, biologia do câncer e desenvolvimento terapêutico.
Foram encontrados 224 produtos de "Integrinas"
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Natalizumab
CAS:<p>Natalizumab used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease.</p>Pureza:98.00%Cor e Forma:LiquidPeso molecular:N/ALifitegrast
CAS:<p>Lifitegrast (SAR 1118) is a lymphocyte, function-associated antigen-1 antagonist.</p>Fórmula:C29H24Cl2N2O7SPureza:99.39% - 99.66%Cor e Forma:SolidPeso molecular:615.48Irigenin
CAS:<p>Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the Extra</p>Fórmula:C18H16O8Pureza:99.50% - 99.85%Cor e Forma:SolidPeso molecular:360.31Carotegrast methyl
CAS:<p>Carotegrast methyl (AJM300), an orally-active small molecule, can antagonize the α4 integrin receptor. It is a specific and dual α4β1/α4β7 integrin antagonist.</p>Fórmula:C28H26Cl2N4O5Pureza:99.26% - 99.72%Cor e Forma:SolidPeso molecular:569.44Tirofiban hydrochloride monohydrate
CAS:<p>Tirofiban（MK383） hydrochloride monohydrate is a non-peptide glycoprotein IIb/IIIa antagonist. Cost-effective and quality-assured.</p>Fórmula:C22H39ClN2O6SPureza:98.81% - >99.99%Cor e Forma:White SolidPeso molecular:495.07E7820
CAS:<p>E7820 (ER68203-00) is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).</p>Fórmula:C17H12N4O2SPureza:98.31% - 99.11%Cor e Forma:SolidPeso molecular:336.37ILK-IN-3
CAS:ILK-IN-3 is an inhibitor of integrin linked kinase, and with antitumor activity.Fórmula:C10H12N6OPureza:99.69%Cor e Forma:SolidPeso molecular:232.24Cyclo(RGDyK) trifluoroacetate
CAS:<p>Cyclo(RGDyK) trifluoroacetate is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.</p>Fórmula:C31H43F6N9O12Pureza:95.28% - ≥95%Cor e Forma:SolidPeso molecular:847.72TR-14035
CAS:<p>TR-14035 (MDK-1191) is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM).</p>Fórmula:C24H21Cl2NO5Pureza:98.98%Cor e Forma:SolidPeso molecular:474.33BIO-1211
CAS:<p>BIO-1211 is a more potent inhibitor of α4β1 (VLA-4, IC50 = 4 nM) over α4β7(IC50 = 2 μM).</p>Fórmula:C36H48N6O9Pureza:99.33%Cor e Forma:SolidPeso molecular:708.8Eptifibatide acetate (148031-34-9 free base)
CAS:<p>Eptifibatide acetate (148031-34-9), a cyclic heptapeptide GP IIb/IIIa inhibitor antiplatelet drug.</p>Fórmula:C35H49N11O9S2·xC2H4O2Pureza:99.7% - 99.87%Cor e Forma:SolidPeso molecular:831.96 (free base)GPRP acetate (67869-62-9 free base)
CAS:<p>GPRP acetate (Pefabloc FG) is fibrinogen-related peptides, which inhibit the interaction of fibrinogen with the platelet membrane glycoprotein IIbIIIa complex.</p>Fórmula:C20H35N7O7Pureza:>99.99%Cor e Forma:SolidPeso molecular:485.53Bexotegrast
CAS:<p>Bexotegrast (PLN-74809) is an αvβ6 and αvβ1 integrin inhibitor with antifibrotic properties for the study of idiopathic pulmonary fibrosis (IPF).</p>Fórmula:C27H36N6O3Pureza:99.53%Cor e Forma:SolidPeso molecular:492.61Etaracizumab
CAS:<p>Etaracizumab (LM 609) is a humanized monoclonal antibody targeting integrin αvβ3, inhibiting angiogenesis and melanoma growth, used in the study of melanoma.</p>Pureza:96.77% (SEC-HPLC) - 99.32% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:144.3 (kDa)Muromonab
CAS:<p>Muromonab (OKT3) is a mouse-derived antibody targeting the CD3 receptor, blocking all cytotoxic T cell functions.</p>Pureza:95% - 97.51% (SEC-HPLC)Cor e Forma:LiquidRO0270608
CAS:<p>RO0270608 is an α4β1/α4β7 integrin antagonist with anti-inflammatory activity for the study of allergic inflammatory responses.</p>Fórmula:C24H19Cl3N2O4Pureza:98.26%Cor e Forma:SolidPeso molecular:505.78Voxalatamab
CAS:<p>Voxalatamab (JNJ-63898081), an IgG4 bispecific antibody targeting PSMA and CD3, demonstrates anti-cancer efficacy in prostate cancer research [1].</p>Cor e Forma:LiquidRovelizumab
CAS:<p>Rovelizumab: humanized anti-CD11/CD18 antibody for MS, hemorrhagic shock, MI, and stroke research.</p>Cor e Forma:LiquidVepsitamab
CAS:<p>Vepsitamab (AMG 199), an anti-MUC17/CD3 BiTE, targets T cells and tumors for cell lysis and T cell activation.</p>Cor e Forma:LiquidCevostamab
CAS:<p>Cevostamab (BFCR4350A, RG6160, RO7187797) is a humanized BsAb IgG1 targeting FcRH5 on MM cells and CD3 on T cells to enhance T-cell-mediated MM cell killing.</p>Cor e Forma:Liquid
