Ferroptose
A ferroptose é uma forma de morte celular regulada caracterizada pelo acúmulo de peróxidos lipídicos e estresse oxidativo dependente de ferro. Ao contrário da apoptose, a ferroptose não é impulsionada por caspases, mas pelo fracasso das defesas antioxidantes celulares, levando à morte celular. Inibidores e indutores de ferroptose são críticos para estudar essa via única de morte celular, que está implicada em várias doenças, incluindo câncer, neurodegeneração e lesão por isquemia-reperfusão. Na CymitQuimica, oferecemos uma ampla gama de moduladores de ferroptose de alta qualidade para apoiar sua pesquisa em mecanismos de morte celular, estresse oxidativo e patologia de doenças.
Foram encontrados 215 produtos de "Ferroptose"
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SP600125
CAS:<p>SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 nM) with oral potency, reversibility, and ATP-competitive</p>Fórmula:C14H8N2OPureza:97.63% - 99.82%Cor e Forma:SolidPeso molecular:220.23L-Cystine
CAS:<p>L-Cystine (Cystine Acid) is not considered one of the 20 amino acids, L-Cystine (Cystine Acid) is a sulfur-containing derivative obtained from oxidation of</p>Fórmula:C6H12N2O4S2Pureza:99.59% - 99.85%Cor e Forma:White Solid PowderPeso molecular:240.30Rosiglitazone
CAS:<p>Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity.</p>Fórmula:C18H19N3O3SPureza:98.61% - 99.87%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:357.43L-Glutamic acid
CAS:<p>L-Glutamic acid is an agonist of glutamate receptors, including metabotropic glutamate receptors (mGluR), AMPA, NMDA, and KA. High-Quality, Low-Cost!</p>Fórmula:C5H9NO4Pureza:99.14% - 99.55%Cor e Forma:White Solid CrystallinePeso molecular:147.13ML385
CAS:<p>ML385 is an NRF2 inhibitor (IC50=1.9 μM) with novelty and specificity.</p>Fórmula:C29H25N3O4SPureza:98.08% - >99.99%Cor e Forma:SolidPeso molecular:511.59Trigonelline
CAS:<p>Trigonelline (Trigenolline), an alkaloid with potential antidiabetic activity, is present in considerable amounts in coffee.</p>Fórmula:C7H7NO2Pureza:97.585% - 99.49%Cor e Forma:Prisms Aqueous From Alcohol + Water SolidPeso molecular:137.14PRIMA-1
CAS:<p>PRIMA-1 (NSC-281668) is a mutant p53 reactivator. It induces apoptosis and inhibits growth of human tumors with mutant p53.</p>Fórmula:C9H15NO3Pureza:99.22%Cor e Forma:SolidPeso molecular:185.22Atorvastatin hemicalcium salt
CAS:<p>Atorvastatin hemicalcium salt (Atorvastatin Calcium) is an orally HMG-CoA reductase inhibitor that lowers cholesterol. Cost-effective and quality-assured.</p>Fórmula:C33H34FN2O5CaPureza:99.27% - >99.99%Cor e Forma:White Crystalline PowderPeso molecular:577.67Erastin
CAS:<p>Erastin is an iron death activator that acts on the mitochondrial VDAC in a ROS- and iron-dependent manner, anti-tumor. High-Quality, Low-Cost!</p>Fórmula:C30H31ClN4O4Pureza:98% - 99.75%Cor e Forma:SolidPeso molecular:547.04FIN56
CAS:<p>FIN56 is a specific inducer of ferroptosis.</p>Fórmula:C25H31N3O5S2Pureza:99.72% - 99.78%Cor e Forma:SolidPeso molecular:517.66PD146176
CAS:<p>PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM.</p>Fórmula:C15H11NSPureza:98.00%Cor e Forma:SolidPeso molecular:237.32Pifithrin-α hydrobromide
CAS:<p>Pifithrin-α hydrobromide (Pifithrin-α hydrobromide) is a p53 inhibitor, inhibiting p53-dependent transactivation of p53-responsive genes.</p>Fórmula:C16H18N2OS·HBrPureza:97.71% - >99.99%Cor e Forma:SolidPeso molecular:367.3Pifithrin-β hydrobromide
CAS:<p>Pifithrin-β hydrobromide (Cyclic PFT-α) is an inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apoptosis.</p>Fórmula:C16H17BrN2SPureza:99.24% - 99.74%Cor e Forma:SolidPeso molecular:349.29Levobupivacaine hydrochloride
CAS:<p>Levobupivacaine hydrochloride ((S)-(-)-Bupivacaine monohydrochloride) is a reversible neuronal sodium channel inhibitor, used as a long-acting local anesthetic.</p>Fórmula:C18H28N2O·HClPureza:99.74%Cor e Forma:White Crystalline PowderPeso molecular:324.89Ammonium iron(III) citrate
CAS:<p>Ammonium iron(III) citrate (Ferric ammonium citrate) is a physiological form of non-ferritin-bound iron that causes intracellular iron overload and iron death.</p>Fórmula:C24H32Fe3N3O28Pureza:98%Cor e Forma:Ferric Ammonium Citrate Is A Yellowish Brown To Red Solid With A Faint Odor Of AmmoniaPeso molecular:978.05U-73122
CAS:<p>U-73122 (U73122) , an effective PLC inhibitor, reduces agonist-induced Ca2+ increases in platelets and PMN.</p>Fórmula:C29H40N2O3Pureza:97.50%Cor e Forma:Solid Off-WhitePeso molecular:464.64UAMC-3203
CAS:<p>UAMC-3203 is a potent and selective Ferroptosis inhibitor (IC50: 12 nM).</p>Fórmula:C25H37N5O2SPureza:97.052% - 99.72%Cor e Forma:SolidPeso molecular:471.66FINO2
CAS:<p>FINO2, a strong ferroptosis trigger, blocks GPX4, oxidizes Fe2+, stable in different pH, causes lipid peroxidation.</p>Fórmula:C15H28O3Pureza:97.27%Cor e Forma:SoildPeso molecular:256.38Microtubule inhibitor 8
CAS:<p>Microtubule Inhibitor 8 (MP-HJ-1b) serves as a potent disruptor of microtubule function, inducing cell death via ferroptosis and demonstrating anti-tumor effects [1] [2].</p>Fórmula:C21H15N3O2SCor e Forma:SolidPeso molecular:373.43Pioglitazone-d4
CAS:<p>Pioglitazone D4 is a deuterium labeled Pioglitazone. Pioglitazone is a agonist of PPARγ .</p>Fórmula:C19H20N2O3SPureza:98%Cor e Forma:SolidPeso molecular:360.46
