Microtúbulo associado
Os inibidores de proteínas associadas aos microtúbulos têm como alvo as proteínas que interagem com os microtúbulos, os componentes estruturais do citoesqueleto da célula que são essenciais para a divisão celular. Essas proteínas regulam a estabilidade e a dinâmica dos microtúbulos durante a mitose. A inibição de proteínas associadas aos microtúbulos pode interromper a função dos microtúbulos, levando à parada do ciclo celular e à apoptose, especialmente em células cancerígenas de rápida divisão. Esses inibidores são amplamente utilizados na pesquisa do câncer e no desenvolvimento de medicamentos. Na CymitQuimica, oferecemos uma ampla gama de inibidores de proteínas associadas aos microtúbulos de alta qualidade para apoiar sua pesquisa em divisão celular, dinâmica do citoesqueleto e terapia do câncer.
Foram encontrados 262 produtos de "Microtúbulo associado"
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MAP4343
CAS:<p>Map4343, a 3-methyl ether pregnenolone derivative, binds MAP2, boosts tubulin polymerization, spurs neurite growth, and guards neurons.</p>Fórmula:C22H34O2Pureza:97.024%Cor e Forma:SolidPeso molecular:330.5Suprafenacine
CAS:<p>Suprafenacine (N'-[(E)-(4-methylphenyl)methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide) is a cell-permeable microtubule destabilizer that induces</p>Fórmula:C16H18N4OPureza:99.91%Cor e Forma:SolidPeso molecular:282.34MMAF
CAS:<p>MMAF (MonoMethyl auristatin F), an antimitotic agent, inhibits cell division by blocking the polymerization of tubulin.</p>Fórmula:C39H65N5O8Pureza:97.00% - 99.88%Cor e Forma:SolidPeso molecular:731.96LP-261
CAS:<p>LP-261 is a novel tubulin targeting anticancer agent that binds at the colchicine site on tubulin, inducing G2/M arrest.</p>Fórmula:C22H19N3O4SPureza:99.91%Cor e Forma:SolidPeso molecular:421.47Tirbanibulin
CAS:<p>Tirbanibulin (KX2-391) is a highly selective Src kinase inhibitor that has demonstrated efficacy in pre-Clinicalal animal models of a variety of cancers.</p>Fórmula:C26H29N3O3Pureza:99.43% - 99.67%Cor e Forma:SolidPeso molecular:431.53D-64131
CAS:<p>D-64131 is a tubulin polymerization inhibitor with an IC50 value of 0.53 μM.</p>Fórmula:C16H13NO2Pureza:99.48% - 99.67%Cor e Forma:SolidPeso molecular:251.28Clanfenur
CAS:<p>Clanfenur belongs to a new group of substituted benzoylphenylureas. The drug shows both in vitro and in vivo antitumour activity.</p>Fórmula:C16H15ClFN3O2Pureza:99.93%Cor e Forma:SolidPeso molecular:335.76Curvulin
CAS:<p>Curvulin is the active metabolite isolated from Paraphoma sp. VIZR 1.46. Curvularin inhibits iNOS expression and microtubule assembly.</p>Fórmula:C12H14O5Pureza:98.65%Cor e Forma:SolidPeso molecular:238.24Valecobulin
CAS:Valecobulin is a potent β-tubulin polymerization inhibitor. Valecobulin is a valine prodrug of (S516) and an avascular disrupting compound.Fórmula:C26H28N6O5SPureza:98%Cor e Forma:SolidPeso molecular:536.64-Isopropoxybenzoic acid
CAS:<p>4-Isopropoxybenzoic acid (AI3 12104) is a Centromere-Associated Protein E inhibitor.</p>Fórmula:C10H12O3Pureza:99.88%Cor e Forma:White To Off-White PowderPeso molecular:180.2NQTrp
CAS:<p>NQTrp is an inhibitor of the aggregation of the tau protein with generic anti-amyloidogenic effects.</p>Fórmula:C21H16N2O4Pureza:98.35%Cor e Forma:SolidPeso molecular:360.36Semorinemab
CAS:<p>Semorinemab (RG6100) is a humanised monoclonal antibody targeting the N-terminal domain of tau protein with a Kd of 3.8 nM, suitable for Alzheimer's disease.</p>Pureza:95% - 95%Cor e Forma:LiquidGosuranemab
CAS:<p>Gosuranemab (BMS-986168), a humanized IgG4 mAb, targets tau residues 15-22, and may aid in Alzheimer’s research.</p>Pureza:95% - 95%Cor e Forma:Liquid4-Desacetylvinblastine hydrazide
CAS:<p>Deacetylvinblastine hydrazide, a cytotoxic vinca alkaloid often conjugated with folic acid to produce EC145, a novel folate-receptor targeted agent.</p>Fórmula:C43H56N6O7Cor e Forma:SolidPeso molecular:768.94ST-401
CAS:<p>ST-401, a microtubule-targeting agent (MTA), functions as a brain-penetrant microtubule (MT) assembly inhibitor. It disrupts microtubule (MT) function by gently and reversibly reducing MT assembly, which leads to mitotic delay and interphase cell death. ST-401 demonstrates potent antitumor activity.</p>Fórmula:C24H20N2OCor e Forma:SolidPeso molecular:352.43Posdinemab
CAS:<p>Posdinemab, a humanized IgG1κ antibody, targets the microtubule-associated protein tau (MAPT) [1].</p>Cor e Forma:LiquidTubulin polymerization-IN-2
CAS:<p>Tubulin-IN-2, anticancer β-tubulin binder, IC50 0.92 μM, effective against various cancers.</p>Fórmula:C17H12F2N2O2Cor e Forma:SolidPeso molecular:314.29Auristatin F
CAS:<p>Auristatin F is an effective inhibitor of microtubule and vascular damaging agent. Auristatin F can be used in antibody-drug conjugates.</p>Fórmula:C40H67N5O8Pureza:98.41% - 99.25%Cor e Forma:SolidPeso molecular:745.99Tubulin polymerization-IN-15
CAS:<p>Tubulin polymerization-IN-15 (compound 4) is a highly effective inhibitor of tubulin polymerization, with significant potential in cancer research [1].</p>Fórmula:C18H17N3O4Cor e Forma:SolidPeso molecular:339.35DJ101
CAS:<p>DJ101: A stable tubulin inhibitor that bypasses multidrug resistance efflux pumps.</p>Fórmula:C23H20N4O3Pureza:98%Cor e Forma:SolidPeso molecular:400.43
