PKC
Os inibidores de PKC (Proteína Cinase C) têm como alvo a família de cinases serina/treonina PKC, que estão envolvidas em uma ampla gama de processos celulares, incluindo regulação do ciclo celular, apoptose e diferenciação. A PKC desempenha um papel crucial nas vias de transdução de sinais que influenciam a proliferação e sobrevivência celular. Inibir a PKC pode levar a alterações na progressão do ciclo celular, tornando esses inibidores valiosos na pesquisa relacionada ao câncer, neurobiologia e doenças cardiovasculares. Na CymitQuimica, oferecemos uma seleção diversificada de inibidores de PKC de alta qualidade para apoiar sua pesquisa em transdução de sinais, regulação do ciclo celular e desenvolvimento terapêutico.
Foram encontrados 102 produtos de "PKC"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
[Ala107]MBP(104-118)
CAS:<p>Synthetic peptide analog of bovine myelin basic protein (MBP). Non-competitive inhibitor of PKC (IC50 = 46 - 145 mM).</p>Fórmula:C67H104N20O19Pureza:98%Cor e Forma:SolidPeso molecular:1493.681-Oleoyl-2-acetyl-sn-glycerol
CAS:<p>1-Oleoyl-2-acetyl-sn-glycerol (1-oleoyl-2-acetyl-glycerol) is a PKC activator that induces superoxide production.</p>Fórmula:C23H42O5Cor e Forma:SolidPeso molecular:398.58PKCiota-IN-2
CAS:<p>PKCiota-IN-2 selectively inhibits PKC-ι (IC50=2.8nM) and also blocks PKC-α, ε (IC50s=71nM, 350nM).</p>Fórmula:C24H21N5OPureza:98.86%Cor e Forma:SolidPeso molecular:395.46Aurothiomalate tetramer sodium
<p>Aurothiomalate tetramer sodium, a tetrameric form of Aurothiomalate sodium, functions as an anti-arthritis gold agent. It also acts as a potent and selective inhibitor of the oncogenic PKCι signaling pathway.</p>Cor e Forma:Odour SolidBisindolylmaleimide III
CAS:<p>Bisindolylmaleimide III is a potent and selective inhibitor of protein kinase C (PKC).Bisindolylmaleimide III selectively interacts with PKCα or ribosomal S6</p>Fórmula:C23H20N4O2Pureza:98.6%Cor e Forma:SolidPeso molecular:384.43Lys-arg-ala-lys-ala-lys-thr-thr-lys-lys-arg
CAS:<p>Lys-arg-ala-lys-ala-lys-thr-thr-lys-lys-arg is a protein kinase C substrate.</p>Fórmula:C56H110N22O14Pureza:98%Cor e Forma:SolidPeso molecular:1315.61LY 379196
<p>LY 379196, a potent PKC-β inhibitor (IC 50: 50 nM for PKC βI and 30 nM for PKC βII), effectively suppresses the proliferation of bovine retinal microvascular endothelial cells (BREC) induced by VEGF, IGF-1, and bFGF. This compound serves as an antiproliferative agent for proliferative retinopathy.</p>Fórmula:C30H34N4O5SCor e Forma:SolidPeso molecular:562.68(8R)-8-Hydroxyepoxyboetirane A
<p>(8R)-8-Hydroxyepoxyboetirane A is a neuroactivating compound that interacts with PKCδ-C1B. This compound binds into the PKC enzyme pocket through hydrogen bonds with glycine-253, leucine-251, and threonine-242. It induces the release of NRG1 and promotes the differentiation of neural stem cells into neurons. (8R)-8-Hydroxyepoxyboetirane A holds potential for research into nervous system disorders.</p>Cor e Forma:Odour SolidPKCδ Peptide Substrate
CAS:<p>PKCδ Peptide Substrate is a highly specific substrate for the δ-type of Protein kinase C, composed of a sequence that mirrors murine eEF-1α (422-443) and</p>Fórmula:C109H191N35O29SCor e Forma:SolidPeso molecular:2487.97Protein kinase C α peptide TFA
CAS:<p>Protein Kinase C (alpha) Peptide (TFA) is a PKC-α-associated peptide functioning as a lipid-dependent serine/threonine protein kinase.</p>Fórmula:C68H115F3N24O26SCor e Forma:SolidPeso molecular:1773.85Protein Kinase C (19-31)
CAS:<p>Protein Kinase C (19-31), a PKC inhibitor derived from PKCa, has a serine at position 25 and tests PKC activity.</p>Fórmula:C67H118N26O16Pureza:98%Cor e Forma:Lyophilized PowderPeso molecular:1543.82[Ala113]MBP(104-118)
CAS:<p>Synthetic peptide analog of bovine myelin basic protein (MBP). Non-competitive inhibitor of PKC (IC50 = 28 - 62 mM).</p>Fórmula:C67H104N20O19Pureza:98%Cor e Forma:SolidPeso molecular:1493.68Protein Kinase C (19-36)
CAS:<p>Protein Kinase C (19-36) is a pseudosubstrate peptide inhibitor of protein kinase C (PKC), with an IC50 of 0.18 μM.</p>Fórmula:C93H159N35O24Pureza:98%Cor e Forma:SolidPeso molecular:2151.48PKC β pseudosubstrate
CAS:<p>Selective cell-permeable peptide inhibitor of protein kinase C (IC50 ~ 0.5 μM).</p>Fórmula:C177H294N62O38S3Pureza:98%Cor e Forma:SolidPeso molecular:3994.84K-252b
CAS:<p>K-252b, an indolocarbazole derived from the actinomycete Nocardiopsis, functions as a protein kinase C (PKC) inhibitor.</p>Fórmula:C26H19N3O5Pureza:98%Cor e Forma:Ready-To-Use SolutionPeso molecular:453.45PKC-θ inhibitor
CAS:<p>PKC-theta inhibitor is PKC-θinhibitor, with an IC50 of 12 nM.</p>Fórmula:C20H25F3N6O3Pureza:99.46%Cor e Forma:SolidPeso molecular:454.45(±)-1,2-Diolein
CAS:<p>(±)-1,2-Diolein (1,2-Dioleoyl-rac-glycerol) (1,2-Dioleoyl-rac-glycerol) is a PKC activator. (±)-1,2-Diolein could increases myotubes Ca 2+ influx.</p>Fórmula:C39H72O5Cor e Forma:SolidPeso molecular:620.99Protein kinase inhibitor H-7 dihydrochloride
CAS:<p>Protein kinase inhibitor H-7 dihydrochloride(H-7 dihydrochloride) is a potent protein kinase C (PKC) inhibitor.</p>Fórmula:C14H19Cl2N3O2SPureza:99.54%Cor e Forma:White Crystalline SolidPeso molecular:364.29Taurochenodeoxycholic Acid
CAS:<p>Taurochenodeoxycholic Acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid.</p>Fórmula:C26H45NO6SPureza:99.53% - 99.86%Cor e Forma:SolidPeso molecular:499.7HA-100
CAS:<p>HA-100 is an inhibitor of protein kinase</p>Fórmula:C13H15N3O2SPureza:99.44%Cor e Forma:Pale Yellow Crystalline SolidPeso molecular:277.34
![[Ala107]MBP(104-118)](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTP1887.webp&w=3840&q=75)
![[Ala113]MBP(104-118)](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTP1888.webp&w=3840&q=75)
