Dinamina
Os inibidores de dinamina têm como alvo a dinamina, uma enzima GTPase que desempenha um papel crucial na endocitose, no tráfego de vesículas e na citocinese. A dinamina está envolvida na cisão de vesículas a partir de membranas e é essencial para a distribuição adequada dos componentes celulares durante a divisão celular. Inibir a dinamina pode interromper esses processos, levando a defeitos na divisão celular e induzindo a parada do ciclo celular. Os inibidores de dinamina são valiosos no estudo da endocitose, divisão celular e dinâmica de membranas. Na CymitQuimica, oferecemos uma gama de inibidores de dinamina de alta qualidade para apoiar sua pesquisa em biologia celular, tráfego de membranas e regulação do ciclo celular.
Foram encontrados 26 produtos para "Dinamina".
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TAT-P110
CAS:TAT-P110 is a peptide inhibitor that disrupts the interaction between Drp1 and Fis1, effectively reducing pathological changes in various models of neurodegenerative diseases, ischemia, and sepsis without impairing the physiological function of Drp1.Fórmula:C100H178N44O26Cor e Forma:SolidPeso molecular:2412.76DynaMin inhibitory peptide, myristoylated
CAS:Cell-permeable dynamin inhibitor; blocks its binding to amphiphysin, hindering endocytosis; curbs NMDA receptor internalization.Fórmula:C61H107N19O14Pureza:98%Cor e Forma:SolidPeso molecular:1330.64Dynamin inhibitory peptide TFA
Dynamin inhibitory peptide TFA hinders dynamin-amphiphysin interaction and endocytosis, affecting dopamine D3 and GABA A receptors.Fórmula:C49H81F3N18O16Cor e Forma:SolidPeso molecular:1235.27IIQLPEIVVV TFA
IIQLPEIVVV TFA serves as a specific inhibitor targeting the Drp1-Mff interaction. This compound discriminates between physiological and pathological fission, hindering physiological fission which leads to mitochondrial dysfunction. IIQLPEIVVV TFA is also utilized in research related to Huntington's disease.Fórmula:C54H95N11O14·xC2HF3O2Cor e Forma:SolidPeso molecular:1122.40 (free base)ES9-17
CAS:ES9-17, an ES9 analog, blocks clathrin-mediated endocytosis and impairs Arabidopsis root growth, affecting FM4-64 and transferrin uptake.Fórmula:C10H8BrNO2S2Pureza:99.95%Cor e Forma:SolidPeso molecular:318.21Ref: TM-T64368
5mg52,00€1mL*10mM (DMSO)55,00€10mg78,00€25mg119,00€50mg172,00€100mg259,00€200mg388,00€Dynamin IN-2
CAS:Dynamin IN-2 (compound 43) is a Wiskostatin analogue.Fórmula:C22H21ClN2OPureza:99.40% - 99.52%Cor e Forma:SolidPeso molecular:364.87Ref: TM-T64369
1mg133,00€5mg314,00€1mL*10mM (DMSO)324,00€10mg416,00€25mg632,00€50mg847,00€100mg1.134,00€200mg1.513,00€Schaftoside
CAS:Schaftoside (APIGENIN-6-GLUCOSIDE-8-ARABINOSIDE) has antioxidant and anticancer activity.Fórmula:C26H28O14Pureza:98% - >99.99%Cor e Forma:SolidPeso molecular:564.49Ref: TM-T3898
1mg39,00€5mg80,00€1mL*10mM (DMSO)89,00€10mg105,00€25mg200,00€50mg295,00€100mg442,00€200mg620,00€Mdivi-1
CAS:Mdivi-1 (Mitochondrial division inhibitor 1) is a mitochondrial division inhibitor that inhibits DRP1 and Dynamin I (IC50=1-10 μM).Fórmula:C15H10Cl2N2O2SPureza:96.57% - 99.23%Cor e Forma:SolidPeso molecular:353.22Ref: TM-T1907
5mg44,00€1mL*10mM (DMSO)48,00€10mg52,00€25mg95,00€50mg144,00€100mg215,00€200mg319,00€500mg530,00€Dynasore
CAS:Dynasore, a cell-permeable dynamin inhibitor, blocks GTPase of dynamin 1/2 and Drp1 (IC50: 15 μM) without affecting other small GTPases.Fórmula:C18H14N2O4Pureza:95.85% - 99.22%Cor e Forma:SolidPeso molecular:322.31Ref: TM-T1848
5mg50,00€10mg74,00€1mL*10mM (DMSO)82,00€25mg133,00€50mg245,00€100mg354,00€200mg530,00€500mg837,00€Tetradecyltrimethylammonium bromide
CAS:Tetradecyltrimethylammonium bromide (MitMAB) is a Dynamin GTPase activity inhibitor and a cationic surfactant with asymmetrical structure.Fórmula:C17H38BrNPureza:99.80%Cor e Forma:SolidPeso molecular:336.39Trimethyloctadecylammonium bromide
CAS:Trimethyloctadecylammonium bromide is an inhibitor of Dynamin I(IC50 : 1.9 μM) and also inhibits Dynamin Ⅱ.Fórmula:C21H46N·BrPureza:99.09%Cor e Forma:Solid SolidPeso molecular:392.5Dynamin inhibitory peptide, myristoylated acetate
Myristoylated acetate peptide inhibits DynaMin, blocking amphiphysin binding; myristoylated TFA variant hinders endocytosis.Fórmula:C63H111N19O16Pureza:99.42%Cor e Forma:SolidPeso molecular:1390.67Hydroxy-Dynasore
CAS:Hydroxy-Dynasore (Dyngo-4a) , a effective dynamin inhibitor, inhibits withDynI (brain), DynI (rec), and DynII (rec) of IC50 of 0.38 μM, 1.1 μM, and 2.3 μM,Fórmula:C18H14N2O5Pureza:97.60% - >99.99%Cor e Forma:SolidPeso molecular:338.31Ref: TM-T6822
5mg52,00€1mL*10mM (DMSO)52,00€10mg79,00€25mg130,00€50mg210,00€100mg313,00€200mg465,00€500mg742,00€DNM1 Protein, Human, Recombinant (His)
Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP.Cor e Forma:Lyophilized PowderPeso molecular:32.2 kDa (predicted)Ref: TM-TMPH-01254
5µg78,00€10µg111,00€20µg178,00€50µg268,00€100µg384,00€200µg592,00€500µg1.054,00€1mg1.648,00€Ellipticine quinone
CAS:Ellipticine quinone (NSC-383230) outperforms mdivi-1 in inhibiting Drp1, reduces lung cancer growth, and lessens IR injury by curbing mitochondrial issues.Fórmula:C15H8N2O2Cor e Forma:SolidPeso molecular:248.24Drp1 peptide inhibitor P110
CAS:Compound P110 (Drp1 peptide inhibitor P110) is a selective Drp1 peptide inhibitor with neuroprotective effects. It inhibits the activation of Drp1, prevents Drp1 mitochondrial translocation induced by MPTP, and alleviates dopamine neuron loss, dopaminergic terminal damage, and behavioral deficits caused by MPTP. This compound is useful for Alzheimer's disease research. Additionally, Compound P110 reduces mitochondrial and organ damage in animal models of Huntington's disease, cerebral ischemia, and myocardial infarction.Fórmula:C100H179N45O25Cor e Forma:SolidPeso molecular:2411.78Drp1-IN-1
CAS:Drp1-IN-1 (comp A-7) is a Drp1 protein inhibitor (IC50: 0.91 μM).Fórmula:C22H24N8OSCor e Forma:SolidPeso molecular:448.54Dynamin IN-1
CAS:Dynamin IN-1 is a potent dynamin inhibitor with an IC 50 value of 1.0 µM .Fórmula:C23H24N2OCor e Forma:SolidPeso molecular:344.45DRP1i27
CAS:DRP1i27 inhibits human Drp1 at GTPase site, prevents mitochondrial fission, and shields cells from ischemia-reperfusion damage.Fórmula:C20H26N6OCor e Forma:SolidPeso molecular:366.46MB 0223
CAS:DRP1 partial inhibitor (IC50 = 1.2 μM), selective over OPA1/DYN1, boosts mtDNA in mfn1-knockout MEFs.Fórmula:C26H27N5OSCor e Forma:SolidPeso molecular:457.59
