Nucleosídeo Antimetabólito/Análogo
Antimetabólitos e análogos de nucleosídeos são compostos que imitam nucleosídeos naturais e são incorporados no DNA durante a replicação, levando à terminação da cadeia ou à inibição da síntese de DNA. Esses compostos são amplamente utilizados como agentes quimioterápicos no tratamento de câncer e infecções virais. Ao interromper a síntese de DNA, análogos de nucleosídeos induzem a parada do ciclo celular e a apoptose. Na CymitQuimica, oferecemos uma ampla gama de antimetabólitos e análogos de nucleosídeos de alta qualidade para apoiar sua pesquisa em tratamento do câncer, terapia antiviral e replicação de DNA.
Foram encontrados 493 produtos para "Nucleosídeo Antimetabólito/Análogo".
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2'-O,4'-C-Methyleneadenosine 5'-monophosphate triethylammonium
2’-O,4’-C-Methyleneadenosine 5’-monophosphate (triethylammonium), a purine nucleoside analog, exhibits wide-ranging antitumor activity against indolent lymphoidFórmula:C23H46N7O7PCor e Forma:SolidPeso molecular:563.63Uridine-5-oxo-acetyl-(9-fluorenylmethyl) ester
Uridine analogue with antitumor effects; inhibits DNA synthesis, induces apoptosis in lymphoid cancers.Fórmula:C24H24N2O9Cor e Forma:SolidPeso molecular:484.46N1-Methyl-3'-O-(2-methoxyethyl) adenosine
N1-Methyl-3’-O-(2-methoxyethyl) adenosine, a purine nucleoside analog, exhibits broad antitumor activity against indolent lymphoid malignancies.Fórmula:C14H21N5O5Cor e Forma:SolidPeso molecular:339.352'-Deoxy-2'-fluoro-N3-[(pyrid-4-yl)methyl]uridine
2’-Deoxy-2’-fluoro-N3-[(pyrid-4-yl)methyl]uridine is a purine nucleoside analog widely known for its antitumor activity, particularly against indolent lymphoidFórmula:C15H16FN3O5Cor e Forma:SolidPeso molecular:337.35'-O-Benzoyl-3'-O-(4-methoxybenzyl)-2'-O,4'-C-methyleneuridine
5’-O-Benzoyl-3’-O-(4-methoxybenzyl)-2’-O,4’-C-methyleneuridine is a purine nucleoside analog with broad antitumor activity, primarily targeting indolentFórmula:C25H24N2O8Cor e Forma:SolidPeso molecular:480.472'-Deoxy-2'-fluoro-N3-[(pyrid-2-yl)methyl]uridine
2’-Deoxy-2’-fluoro-N3-[(pyrid-2-yl)methyl]uridine, a uridine analogue, exhibits potential for antiepileptic applications.Fórmula:C15H16FN3O5Cor e Forma:SolidPeso molecular:337.31-(β-D-Xylofuranosyl)-N6-Isopentenyladenine
1-(β-D-Xylofuranosyl)-N6-Isopentenyladenine is an adenosine analog.Fórmula:C15H21N5O4Cor e Forma:SolidPeso molecular:335.366-Amino-4-methoxy-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine
6-Amino-4-methoxy-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine, a purine nucleoside analogue, exhibits widespread antitumor efficacy, particularly againstFórmula:C11H17N5O5Cor e Forma:SolidPeso molecular:299.28Rev dC(Bz)-5'-amidite
Rev dC(Bz)-5'-amidite, a purine nucleoside analog with antitumor effects, inhibits DNA synthesis and induces apoptosis in lymphoid cancers.Fórmula:C46H52N5O8PCor e Forma:SolidPeso molecular:833.919-(5(R)-C-Methyl-2,3,5-tri-O-benzoyl-D-ribofuranosyl)-6-chloropurine
9-(5(R)-C-Methyl-2,3,5-tri-O-benzoyl-D-ribofuranosyl)-6-chloropurine: A purine analog with antitumor effects, inhibiting DNA synthesis and inducing apoptosis.Fórmula:C32H25ClN4O7Cor e Forma:SolidPeso molecular:613.023'-O-(4,4'-Dimethoxy trityl)-2'-O-(2-methoxyethyl)-5-methyluridine
3’-O-(4,4’-Dimethoxy trityl)-2’-O-(2-methoxyethyl)-5-methyluridine, a purine nucleoside analog, exhibits extensive antitumor properties against indolentFórmula:C34H38N2O9Cor e Forma:SolidPeso molecular:618.67Adenosine Dialdehyde (ADOX)
CAS:Adenosine Dialdehyde, a purine analogue, inhibits SAHH (Ki=3.3 nM), and shows strong anti-tumor effects in vivo.Fórmula:C10H11N5O4Pureza:95%Cor e Forma:SolidPeso molecular:265.23Ref: TM-T22231
5mg52,00€1mL*10mM (DMSO)57,00€10mg66,00€25mg88,00€50mg155,00€100mg225,00€200mg335,00€500mg565,00€2'-O-Methyl-5-methyluridine 5'-triphosphate triethylammonium
2’-O-Methyl-5-methyluridine 5’-triphosphate (triethylammonium), a thymidine analog, exhibits insertional activity in replicated DNA.Fórmula:C29H64N5O15P3Cor e Forma:SolidPeso molecular:815.765'-O-DMTr-2',2'-difluoro-dC(Bz)-methyl phosphonamidite
5’-O-DMTr-2’,2’-difluoro-dC(Bz)-methyl phosphonamidite is a purine nucleoside analog with extensive antitumor activity against indolent lymphoid malignancies.Fórmula:C44H49F2N4O7PCor e Forma:SolidPeso molecular:814.856-O-Methyl-2'-O-methylinosine
6-O-Methyl-2’-O-methylinosine is a purine nucleoside analog known for its broad antitumor activity, particularly against indolent lymphoid malignancies.Fórmula:C12H16N4O5Cor e Forma:SolidPeso molecular:296.283'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine
3’-O-DMT-N2-isobutyryl-2’-O-(2-methoxyethyl)guanosine, a purine nucleoside analog, exhibits broad antitumor activity particularly against indolent lymphoidFórmula:C38H43N5O9Cor e Forma:SolidPeso molecular:713.78N1-Methyl-2'-β-C-methyl inosine
N1-Methyl-2’-beta-C-methyl inosine, a purine nucleoside analog, exhibits broad antitumor activity against indolent lymphoid malignancies through mechanisms thatFórmula:C12H16N4O5Cor e Forma:SolidPeso molecular:296.28N1-Methyl-2'-O-(2-methoxyethyl) guanosine
N1-Methyl-2’-O-(2-methoxyethyl) guanosine, a purine nucleoside analog, exhibits broad antitumor activity against indolent lymphoid malignancies.Fórmula:C14H21N5O6Cor e Forma:SolidPeso molecular:355.358-Chloro-2'-deoxy-2'-fluoro-arabino adenosine
8-Chloro-2’-deoxy-2’-fluoro-arabino adenosine, a purine nucleoside analog, demonstrates broad antitumor activity against indolent lymphoid malignancies.Fórmula:C10H11ClFN5O3Cor e Forma:SolidPeso molecular:303.682-(3-Methyln-propylidene hydrazino) adenosine
2-(3-Methyln-propylidene hydrazino) adenosine: a purine analog with antitumor properties, inhibits DNA synthesis, induces apoptosis.Fórmula:C15H23N7O4Cor e Forma:SolidPeso molecular:365.393,5'-Bis(O-t-butyldimethylsilyl)-2'-O-methyl-5-methyl cytidine
3,5’-Bis(O-t-butyldimethylsilyl)-2’-O-methyl-5-methyl cytidine, a cytidine analog, inhibits DNA methyltransferases (e.g., Zebularine), exhibiting potential antiFórmula:C23H45N3O5Si2Cor e Forma:SolidPeso molecular:499.795'-O-DMTr-2'-O-MOE inosine 3'-P-methyl phosphonamidite
5’-O-DMTr-2’-O-MOE inosine 3’-P-methyl phosphonamidite, a purine nucleoside analog, exhibits extensive antitumor activity specific to indolent lymphoidFórmula:C41H52N5O8PCor e Forma:SolidPeso molecular:773.85N1-(2-Methyl)propyl pseudouridine
N1-(2-Methyl)propyl pseudouridine, a purine analog, targets lymphoid cancer by inhibiting DNA synthesis and inducing apoptosis.Fórmula:C13H20N2O6Cor e Forma:SolidPeso molecular:300.31Isocytosine
CAS:Isocytosine ,with CAS No. 108-53-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Isocytosine provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Fórmula:C4H5N3OCor e Forma:White To Off-White SolidPeso molecular:111.12'-Deoxy-2'-fluoro-N3-(n-dodecyl)uridine
2’-Deoxy-2’-fluoro-N3-(n-dodecyl)uridine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.Fórmula:C21H35FN2O5Cor e Forma:SolidPeso molecular:414.51N1-Methyl-2'-O-(2-methoxyethyl) adenosine
N1-Methyl-2’-O-(2-methoxyethyl) adenosine, a purine nucleoside analog, exhibits broad antitumor effects, particularly against indolent lymphoid malignancies.Fórmula:C14H21N5O5Cor e Forma:SolidPeso molecular:339.355-Aza-xylo-cytidine
5-Aza-xylo-cytidine, a purine analog with antitumor effects, inhibits DNA synthesis and induces apoptosis in lymphoid cancers.Fórmula:C8H12N4O5Cor e Forma:SolidPeso molecular:244.23'-β-C-Methyl-2-thiouridine
3’-β-C-Methyl-2-thiouridine, a purine nucleoside analog, exhibits extensive antitumor activity, particularly against indolent lymphoid malignancies.Fórmula:C10H14N2O5SCor e Forma:SolidPeso molecular:274.29N4-Benzoyl-2'-deoxy-2'-fluoro-β-D-arabinocytidine
N4-Benzoyl-2’-deoxy-2’-fluoro-β-D-arabinocytidine, a purine nucleoside analog, exhibits widespread antitumor activity, particularly against indolent lymphoidFórmula:C16H16FN3O5Cor e Forma:SolidPeso molecular:349.31N4-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine
N4-Benzoyl-3'-O-DMT cytidine analog inhibits DNA methyltransferases like Zebularine.Fórmula:C41H43N3O9Cor e Forma:SolidPeso molecular:721.79Py-MAA-Val-Cit-PAB-DX8951
CAS:Py-MAA-Val-Cit-PAB-DX8951, a purine toxin, serves as an intermediate in the synthesis of antibody-drug conjugates [1].Fórmula:C57H66FN11O13SCor e Forma:SolidPeso molecular:1164.262-(P-Cyanophenyl methylidene hydrazino) adenosine
2-(P-Cyanophenyl methylidene hydrazino) adenosine: a purine analog with antitumor effects via DNA synthesis inhibition and apoptosis.Fórmula:C18H18N8O4Cor e Forma:SolidPeso molecular:410.39DMT-dG(ib) Phosphoramidite
CAS:DMT-dG(ib) Phosphoramidite can be used to synthesize DNA.Fórmula:C44H54N7O8PPureza:99.21%Cor e Forma:SolidPeso molecular:839.92N6-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl) adenosine
N6-Benzoyl-3'-O-DMT-adenosine is a purine analog with antitumor effects by hindering DNA synthesis and inducing apoptosis.Fórmula:C41H41N5O8Cor e Forma:SolidPeso molecular:731.795'(R)-C-Methyl-5-fluorouridine
5’(R)-C-Methyl-5-fluorouridine, a uridine analogue, possesses potential antiepileptic properties.Fórmula:C10H13FN2O6Cor e Forma:SolidPeso molecular:276.225'-O-(4,4'-Dimethoxy trityl)-2'-O-(2-methoxyethyl) inosine
5’-O-(4,4’-Dimethoxytrityl)-2’-O-(2-methoxyethyl)inosine is a purine nucleoside analog with broad antitumor activity, primarily targeting indolent lymphoidFórmula:C34H36N4O8Cor e Forma:SolidPeso molecular:628.67N6-Methyl-2'-β-C-ethynyl adenosine
N6-Methyl-2’-beta-C-ethynyl adenosine is a purine nucleoside analog.Fórmula:C13H15N5O4Cor e Forma:SolidPeso molecular:305.295-(2-Hydroxyethyl)-2',3'-di-O-toluoyl-2'-deoxyuridine
5-(2-Hydroxyethyl)-2',3'-di-O-toluoyl-2'-deoxyuridine, a purine nucleoside analog, exhibits widespread antitumor activity specifically against indolent lymphoidFórmula:C27H28N2O8Cor e Forma:SolidPeso molecular:508.522-Amino-6-O-methyl-2'-O-methyl purine riboside
2-Amino-6-O-methyl-2’-O-methyl purine riboside, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoidFórmula:C12H17N5O5Cor e Forma:SolidPeso molecular:311.296-Methoxypurine-9-β-D-5'(R)-C-methylriboside
6-Methoxypurine-9-β-D-5’(R)-C-methylriboside, an analog of hypoxanthine—a purine base predominantly found in muscle tissue and a metabolite generated whenFórmula:C12H16N4O5Cor e Forma:SolidPeso molecular:296.28N1-Methylxylo-guanosine
N1-Methylxylo-guanosine, a purine analog, targets lymphoid cancer via DNA synthesis inhibition and apoptosis.Fórmula:C11H15N5O5Cor e Forma:SolidPeso molecular:297.27N1-Benzoyl pseudouridine
N1-Benzoyl pseudouridine, a purine nucleoside analog, inhibits DNA synthesis and induces apoptosis to combat lymphoid cancers.Fórmula:C16H16N2O7Cor e Forma:SolidPeso molecular:348.315'-DMTr-3'dA(Bz)-methylphosphonami dite
5’-DMTr-3’dA(Bz)-methylphosphonamidite, a purine nucleoside analog, exhibits wide-ranging antitumor activity, specifically targeting indolent lymphoidFórmula:C45H51N6O6PCor e Forma:SolidPeso molecular:802.92'-Fluoro-2'-deoxy-arabinoadenosine 5'-triphosphate triethylamine
2’-Fluoro-2’-deoxy-arabinoadenosine 5’-triphosphate (triethylamine) is a purine nucleoside analog with significant antitumor properties, particularly effectiveFórmula:C34H75FN9O12P3Cor e Forma:SolidPeso molecular:913.933'-β-C-Methyl-N6-isopentenyl adenosine
3’-Beta-C-Methyl-N6-isopentenyl adenosine is an adenosine analog.Fórmula:C16H23N5O4Cor e Forma:SolidPeso molecular:349.382'-Chloro-N6-(3-trifluoromethyl)benzyl adenosine
2’-Chloro-N6-(3-trifluoromethyl)benzyl adenosine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoidFórmula:C18H17ClF3N5O4Cor e Forma:SolidPeso molecular:459.812'-O-(2-Methoxyethyl)guanosine 5'-triphosphate ammonium
2’-O-(2-Methoxyethyl)guanosine 5’-triphosphate (ammonium), a purine nucleoside analog, exhibits extensive antitumor properties, particularly against indolentFórmula:C13H34N9O15P3Cor e Forma:SolidPeso molecular:649.38N7-Methyl-2'-O-(2-methoxyethyl) guanosine
N7-Methyl-2’-O-(2-methoxyethyl) guanosine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.Fórmula:C14H21N5O6Cor e Forma:SolidPeso molecular:355.352'-Deoxy-2'-fluoro-N3-[3-(tert-butoxycarbonyl) amino]propyluridine
2’-Deoxy-2’-fluoro-N3-[3-(tert-butoxycarbonyl)amino]propyluridine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolentFórmula:C17H26FN3O7Cor e Forma:SolidPeso molecular:403.4(R)-N-(2,3-Dihydro-1H-indenyl)-2-amino adenosine
(R)-N-(2,3-Dihydro-1H-indenyl)-2-amino adenosine, a purine analog, targets lymphoid cancer via DNA synthesis inhibition and apoptosis.Fórmula:C19H22N6O4Cor e Forma:SolidPeso molecular:398.42
