Nucleosídeo Antimetabólito/Análogo
Antimetabólitos e análogos de nucleosídeos são compostos que imitam nucleosídeos naturais e são incorporados no DNA durante a replicação, levando à terminação da cadeia ou à inibição da síntese de DNA. Esses compostos são amplamente utilizados como agentes quimioterápicos no tratamento de câncer e infecções virais. Ao interromper a síntese de DNA, análogos de nucleosídeos induzem a parada do ciclo celular e a apoptose. Na CymitQuimica, oferecemos uma ampla gama de antimetabólitos e análogos de nucleosídeos de alta qualidade para apoiar sua pesquisa em tratamento do câncer, terapia antiviral e replicação de DNA.
Foram encontrados 1417 produtos de "Nucleosídeo Antimetabólito/Análogo"
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2'-Fluorothymidine
CAS:<p>2'-Fluorothymidine is a selective substrate for TK2, related to thymidine and methyluridine.</p>Fórmula:C10H13FN2O5Pureza:99.67%Cor e Forma:SolidPeso molecular:260.22Fosteabine
CAS:Fosteabine is an oral and prodrug analog of cytarabine. It is resistant to deoxycytidine deaminase.Fórmula:C27H50N3O8PPureza:98%Cor e Forma:SolidPeso molecular:575.67Rabacfosadine succinate
CAS:Rabacfosadine succinate is the acyclic nucleoside phosphonate PMEG double prodrug.Fórmula:C25H41N8O10PPureza:98%Cor e Forma:SolidPeso molecular:644.623Thiamiprine
CAS:<p>Thiamiprine is an agent with the activity of antineoplastic.</p>Fórmula:C9H8N8O2SCor e Forma:SolidPeso molecular:292.282'-Deoxy-L-guanosine
CAS:2'-Deoxy-L-guanosine is a nucleoside that shows antibiotic properties by inhibiting protein synthesis, leading to cell death.Fórmula:C10H13N5O4Cor e Forma:SolidPeso molecular:267.24Guanoctine hydrochloride
CAS:Guanoctine hydrochloride has antihypertensive activity.Fórmula:C9H22ClN3Cor e Forma:SolidPeso molecular:207.745-Ethynyluridine
CAS:<p>5-Ethynyluridine marks new RNA for RICK, capturing proteins on various RNAs, even nonpolyadenylated types.</p>Fórmula:C11H12N2O6Pureza:99.78%Cor e Forma:SolidPeso molecular:268.221-Methylcytosine
CAS:<p>1-Methylcytosine (4-amino-1-methylpyrimidin-2(1H)-one) is a methylated form of the cytosine and can be used as the nucleobase of hachimoji DNA paired with</p>Fórmula:C5H7N3OPureza:99.88%Cor e Forma:SolidPeso molecular:125.13Enocitabine
CAS:Enocitabine is a nucleoside analog.Fórmula:C31H55N3O6Pureza:97.22%Cor e Forma:SolidPeso molecular:565.785-Aminouridine
CAS:5-Aminouridine (4-Chloro-2-isopropyl-5-methylphenol(chlorothymol)) modifies nucleobases and is incorporated into the target DNA.Fórmula:C9H13N3O6Pureza:99.53%Cor e Forma:SolidPeso molecular:259.225-OHdU
CAS:<p>5-OHdU (5-OHdU) is a major oxidation product of 2'-Deoxycytidine and can be incorporated into DNA in vitro.</p>Fórmula:C9H12N2O6Pureza:99.5%Cor e Forma:SolidPeso molecular:244.2GS-6620 PM
CAS:<p>GS-6620 PM, oral Hep C polymerase inhibitor prodrug, is a potent GS-6620 derivative with limited activity against other viruses.</p>Fórmula:C13H15N5O4Pureza:98.52% - 98.7%Cor e Forma:SolidPeso molecular:305.29Peldesine
CAS:Peldesine (BCX 34), an oral purine nucleoside phosphorylase blocker, halts T-cell growth; used in CTCL, psoriasis, HIV research. IC50: 800 nM.Fórmula:C12H11N5OPureza:99.27% - 99.9%Cor e Forma:SolidPeso molecular:241.25Raluridine
CAS:Raluridine is an HIV treatment inhibiting RNA-directed DNA polymerase with IC50 of 1.8 microM, compared to FLT, AZT, ddI, and ddC.Fórmula:C9H10ClFN2O4Pureza:98%Cor e Forma:SolidPeso molecular:264.645′-Guanylyl methylenediphosphonate sodium
CAS:5′-Guanylyl methylenediphosphonate (sodium) serves as a GTP analogue and acts as a specific, competitive inhibitor of the GTP reaction in protein synthesis [1].Fórmula:C11H15N5Na3O13P3Cor e Forma:SolidPeso molecular:587.15CI 972 anhydrous
CAS:CI 972 anhydrous is an inhibitor of purine nucleoside phosphorylase (PNP) (Ki: 0.83 μM) used as a T cell-selective immunosuppressive agent.Fórmula:C11H12ClN5OSPureza:98%Cor e Forma:SolidPeso molecular:297.76Sapacitabine
CAS:Sapacitabine (CS682) is a nucleoside analog precursor with anticancer activity used in the study of leukemia.Fórmula:C26H42N4O5Pureza:98.82%Cor e Forma:SolidPeso molecular:490.64Spirofylline
CAS:Spirofylline is an agent of bronchodilator, has the potential for asthma and bronchitis and emphysema treatment.Fórmula:C24H28N6O5Pureza:98%Cor e Forma:SolidPeso molecular:480.525'-ODMT cEt N-Bz A Phosphoramidite (Amidite)
CAS:<p>5'-ODMT cEt N-Bz A Phosphoramidite Amidite, a locked nucleic acid (LNA) analogue, exhibits hybridization and mismatch discrimination capabilities similar to LNA, and shows resistance to exonuclease digestion [1].</p>Fórmula:C49H54N7O8PCor e Forma:SolidPeso molecular:899.97Homouridine
CAS:Homouridine, an analogue of uridine, functions as an intermediate in the synthesis of MMP-2 inhibitor (compound I, IC50 = 150 μM).Fórmula:C10H14N2O6Pureza:98%Cor e Forma:SolidPeso molecular:258.232'-Deoxypseudoisocytidine
CAS:2'-Deoxypseudoisocytidine is a nucleoside analogue.Fórmula:C9H13N3O4Pureza:98%Cor e Forma:SolidPeso molecular:227.22Fosfluridine tidoxil
CAS:<p>Fosfluridine tidoxil, a thymidylate synthase inhibitor, is used potentially for the treatment of colorectal cancer, and breast cancer.</p>Fórmula:C34H62FN2O10PSCor e Forma:SolidPeso molecular:740.95'-ODMT cEt N-Bzm5 C Phosphoramidite (Amidite)
CAS:<p>5'-ODMT cEt N-Bzm5 C Phosphoramidite is a strong modified nucleic acid analog for antisense oligos.</p>Fórmula:C49H56N5O9PCor e Forma:SolidPeso molecular:889.975'-ODMT cEt m5U Phosphoramidite (Amidite)
CAS:<p>5'-ODMT cEt m5U Phosphoramidite Amidite, a locked nucleic acid (LNA) analog, demonstrates exceptional safety and antisense activity [1] [2].</p>Fórmula:C42H51N4O9PCor e Forma:SolidPeso molecular:786.855'-DMT-5-F-2'-dU Phosphoramidite
CAS:5'-DMT-5-F-2'-dU Phosphoramidite is a nucleoside phosphoramidite analog employed in oligonucleotide synthesis. It plays a crucial role in developing therapeutic oligonucleotides, which are used in crafting drugs for cancer treatment.Fórmula:C39H46FN4O8PCor e Forma:SolidPeso molecular:748.7772′-OMe-ADP
CAS:<p>2′-OMe-ADP is a nucleotide analogue used in oligonucleotide synthesis.</p>Fórmula:C11H17N5O10P2Cor e Forma:SolidPeso molecular:441.23Lobucavir
CAS:<p>Lobucavir (BMS-180194; SQ 34514) is a nucleoside analogue and an antiviral agent with broad-spectrum activity against various viruses, including HBV, HIV/AIDS, and α, β, and γ herpesviruses (including CMV, herpes simplex virus, varicella-zoster virus, and Epstein-Barr virus).</p>Fórmula:C11H15N5O3Cor e Forma:SolidPeso molecular:265.27N6-Benzoyl-2'-deoxy-3'-O-DMT-adenosine
CAS:N6-Benzoyl-2'-deoxy-3'-O-DMT-adenosine is a nucleoside analog that resembles the natural nucleotide adenosine in structure. It acts as an activator of ribonucleotide reductase, facilitating the conversion of ribonucleotides into deoxyribonucleotides.Fórmula:C38H35N5O6Cor e Forma:SolidPeso molecular:657.714Antiangiogenic agent 2
<p>Antiangiogenic agent 2 (compound 3b) is a potent inhibitor of thymidine phosphorylase (IC50: 39.71 μM) and exhibits anti-angiogenic effects.</p>Fórmula:C26H26FN3O4Cor e Forma:SolidPeso molecular:463.5Pseudouridine 5'-OTBDPS
CAS:<p>Pseudouridine5'-OTBDPS [5-(5-O-TBDPS-β-D-ribofuranosyl)uracil] is an intermediate of Pseudouridine.</p>Fórmula:C25H30N2O6SiCor e Forma:SolidPeso molecular:482.60LNA-GMP
CAS:LNA-GMP, a nucleotide analogue, is utilized in the synthesis of oligonucleotides.Fórmula:C11H14N5O8PCor e Forma:SolidPeso molecular:375.23LNA-AMP
CAS:LNA-AMP is a nucleotide analog used in the synthesis of oligonucleotides.Fórmula:C11H14N5O7PCor e Forma:SolidPeso molecular:359.232′-F-UDP
CAS:2′-F-UDP is a nucleotide analogue used in the synthesis of oligonucleotides.Fórmula:C9H13FN2O11P2Cor e Forma:SolidPeso molecular:406.152-Amino-2'-fluoro-2'-deoxyadenosine
CAS:<p>2-Amino-2'-fluoro-2'-deoxyadenosine is a component of nucleic acids.</p>Fórmula:C10H13FN6O3Cor e Forma:SolidPeso molecular:284.25LNA-CTP
CAS:<p>LNA-CTP is a nucleotide analog utilized in the synthesis of oligonucleotides.</p>Fórmula:C10H16N3O14P3Cor e Forma:SolidPeso molecular:495.17LNA-GTP
CAS:LNA-GTP is a nucleotide analog used in the synthesis of oligonucleotides.Fórmula:C11H16N5O14P3Cor e Forma:SolidPeso molecular:535.197-Methylguanosine 5′-monophosphate
CAS:7-Methylguanosine 5′-monophosphate (7-Methylguanylic acid) is a component of nucleic acids.Fórmula:C11H16N5O8PCor e Forma:SolidPeso molecular:377.25Morpholino U subunit
CAS:Morpholino U subunit is one of the fundamental components of morpholino oligonucleotides, capable of pairing with adenine in target RNA.Fórmula:C30H32ClN4O5PCor e Forma:SolidPeso molecular:595.033'-NH-Tr-2',3'-ddG(iBu)-5'-CE-Phosphoramidite
CAS:3'-NH-Tr-2',3'-ddG(iBu)-5'-CE-Phosphoramidite is a nucleoside phosphoramidite monomer featuring protective group modifications, suitable for RNA oligonucleotide synthesis.Fórmula:C42H51N8O5PCor e Forma:SolidPeso molecular:778.888-Azakinetin riboside
CAS:8-Azakinetin riboside, a structural analog of kinetin riboside, exhibits cytotoxic activity [1].Fórmula:C14H16N6O5Peso molecular:348.312′-OMe-GDP
CAS:<p>2′-OMe-GDP is a nucleotide analog utilized for the synthesis of oligonucleotides.</p>Fórmula:C11H17N5O11P2Cor e Forma:SolidPeso molecular:457.232'-O-MOE-UTP
CAS:2'-O-MOE-UTP is a nucleotide analog employed in the synthesis of oligonucleotides.Fórmula:C12H21N2O16P3Cor e Forma:SolidPeso molecular:542.222'-Deoxycytidine hydrate
CAS:2'-Deoxycytidine (Deoxycytidine) hydrate is a component of nucleic acids.Fórmula:C9H15N3O5Cor e Forma:SolidPeso molecular:245.232′-OMe-UDP
CAS:2′-OMe-UDP is a nucleotide analog utilized in the synthesis of oligonucleotides.Fórmula:C10H16N2O12P2Cor e Forma:SolidPeso molecular:418.19LNA-GDP
CAS:LNA-GDP is a nucleotide analog utilized in the synthesis of oligonucleotides.Fórmula:C11H15N5O11P2Cor e Forma:SolidPeso molecular:455.21Dmf-dg
CAS:<p>Dmf-dg (2'-Deoxy-N2-dimethylaminomethylene-guanosine) is a nucleoside of deoxyguanosine (dG) with a dimethylaminomethylene (DMF) base protection, employed in the synthesis of oligonucleotides.</p>Fórmula:C13H18N6O4Cor e Forma:SolidPeso molecular:322.323-deoxy-3-fluoro-β-D-Ribofuranose 25
CAS:Compound 25, β-D-Ribofuranose, 3-deoxy-3-fluoro-, 1,2-diacetate 5-(4-methylbenzoate), exhibits strong activity in inhibiting the growth of tumor cells [1].Fórmula:C17H19FO7Peso molecular:354.332'-O-MOE-GMP
CAS:<p>2'-O-MOE-GMP is a nucleotide analogue that can be utilized in the synthesis of oligonucleotides.</p>Fórmula:C13H20N5O9PCor e Forma:SolidPeso molecular:421.305'-O-Dmt-n2-isobutyryl-2'-o-methyl-d-guanosine
CAS:5'-O-Dmt-n2-isobutyryl-2'-o-methyl-d-guanosine is a nucleoside synthesized through oxime ring-opening at the 5' position and methylation at the 2' position. In chemotaxis assays, 5'-O-Dmt-n2-isobutyryl-2'-o-methyl-d-guanosine demonstrates tissue affinity.Fórmula:C36H39N5O8Cor e Forma:SolidPeso molecular:669.724
