Nucleosídeo Antimetabólito/Análogo
Antimetabólitos e análogos de nucleosídeos são compostos que imitam nucleosídeos naturais e são incorporados no DNA durante a replicação, levando à terminação da cadeia ou à inibição da síntese de DNA. Esses compostos são amplamente utilizados como agentes quimioterápicos no tratamento de câncer e infecções virais. Ao interromper a síntese de DNA, análogos de nucleosídeos induzem a parada do ciclo celular e a apoptose. Na CymitQuimica, oferecemos uma ampla gama de antimetabólitos e análogos de nucleosídeos de alta qualidade para apoiar sua pesquisa em tratamento do câncer, terapia antiviral e replicação de DNA.
Foram encontrados 1416 produtos de "Nucleosídeo Antimetabólito/Análogo"
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Xylocytidine
CAS:Xylocytidine is a biochemical.Fórmula:C9H13N3O5Cor e Forma:SolidPeso molecular:243.22N1-(2-Methyl)propyl pseudouridine
N1-(2-Methyl)propyl pseudouridine, a purine analog, targets lymphoid cancer by inhibiting DNA synthesis and inducing apoptosis.Fórmula:C13H20N2O6Cor e Forma:SolidPeso molecular:300.31Py-MAA-Val-Cit-PAB-DX8951
CAS:<p>Py-MAA-Val-Cit-PAB-DX8951, a purine toxin, serves as an intermediate in the synthesis of antibody-drug conjugates [1].</p>Fórmula:C57H66FN11O13SCor e Forma:SolidPeso molecular:1164.26Flurocitabine HCl
CAS:Fluorocitabine HCl, a cytarabine analog, hydrolyzes into ara-FC and ara-FU, showing antitumor effects in leukemia and solid cancers.Fórmula:C9H11ClFN3O4Pureza:99.23% - 99.76%Cor e Forma:SoildPeso molecular:279.65N4-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine
<p>N4-Benzoyl-3'-O-DMT cytidine analog inhibits DNA methyltransferases like Zebularine.</p>Fórmula:C41H43N3O9Cor e Forma:SolidPeso molecular:721.795'(R)-C-Methyl-5-fluorouridine
<p>5’(R)-C-Methyl-5-fluorouridine, a uridine analogue, possesses potential antiepileptic properties.</p>Fórmula:C10H13FN2O6Cor e Forma:SolidPeso molecular:276.22m7GpppUmpG
CAS:m7GpppUmpG, a trinucleotide cap analogue, enables RNA synthesis with cap 0 or 1 structures.Fórmula:C31H42N12O26P4Cor e Forma:SolidPeso molecular:1122.63Isocytosine
CAS:Compound PDK0016, with CAS No. 108-53-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0016 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Fórmula:C4H5N3OCor e Forma:White To Off-White SolidPeso molecular:111.1TLR7 agonist 12
CAS:<p>TLR7 agonist 12, a purine nucleoside analog, inhibits DNA synthesis and induces apoptosis in lymphoid cancers.</p>Fórmula:C14H19N5O8Cor e Forma:SolidPeso molecular:385.335'-O-DMTr-2',2'-difluoro-dC(Bz)-methyl phosphonamidite
5’-O-DMTr-2’,2’-difluoro-dC(Bz)-methyl phosphonamidite is a purine nucleoside analog with extensive antitumor activity against indolent lymphoid malignancies.Fórmula:C44H49F2N4O7PCor e Forma:SolidPeso molecular:814.85N4-(3,3,3-Trifluoropropanoyl)cytidine
<p>N4-(3,3,3-Trifluoropropanoyl)cytidine, a cytidine analog, inhibits DNA methyltransferases, possibly anti-metabolic and anti-cancer.</p>Fórmula:C12H14F3N3O6Cor e Forma:SolidPeso molecular:353.25Rev 2'-O-MOE-5MeC(Bz)-5'-amidite
<p>Rev 2’-O-MOE-5MeC(Bz)-5’-amidite, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.</p>Fórmula:C50H60N5O10PCor e Forma:SolidPeso molecular:922.016-Amino-3-(furan-2-yl)-4-methoxy-1-(β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine
6-Amino-3-(furan-2-yl)-4-methoxy-1-(β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine, a purine nucleoside analogue, exhibits broad antitumor activity byFórmula:C15H17N5O6Cor e Forma:SolidPeso molecular:363.336-Amino-4-hydrozino-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine
6-Amino-4-hydrozino-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine, a pyrimidine nucleoside analog, boasts a broad spectrum of biochemical andFórmula:C10H17N7O3Cor e Forma:SolidPeso molecular:283.293,5'-Bis(O-t-butyldimethylsilyl)-2'-O-methyl-5-methyl cytidine
3,5’-Bis(O-t-butyldimethylsilyl)-2’-O-methyl-5-methyl cytidine, a cytidine analog, inhibits DNA methyltransferases (e.g., Zebularine), exhibiting potential antiFórmula:C23H45N3O5Si2Cor e Forma:SolidPeso molecular:499.79Adenosine Dialdehyde (ADOX)
CAS:<p>Adenosine Dialdehyde, a purine analogue, inhibits SAHH (Ki=3.3 nM), and shows strong anti-tumor effects in vivo.</p>Fórmula:C10H11N5O4Pureza:95%Cor e Forma:SolidPeso molecular:265.23N4-Benzoyl-2'-deoxy-2'-fluoro-β-D-arabinocytidine
<p>N4-Benzoyl-2’-deoxy-2’-fluoro-β-D-arabinocytidine, a purine nucleoside analog, exhibits widespread antitumor activity, particularly against indolent lymphoid</p>Fórmula:C16H16FN3O5Cor e Forma:SolidPeso molecular:349.31N1-Methyl-2'-O-(2-methoxyethyl) adenosine
N1-Methyl-2’-O-(2-methoxyethyl) adenosine, a purine nucleoside analog, exhibits broad antitumor effects, particularly against indolent lymphoid malignancies.Fórmula:C14H21N5O5Cor e Forma:SolidPeso molecular:339.35N3-[(Pyrid-4-yl)methyl]uridine
<p>N3-[(Pyrid-4-yl)methyl]uridine, a uridine analog, may have antiepileptic properties and aid in researching anticonvulsants and anxiolytics.</p>Fórmula:C15H17N3O6Cor e Forma:SolidPeso molecular:335.312'-Deoxy-2'-fluoro-N3-(n-dodecyl)uridine
<p>2’-Deoxy-2’-fluoro-N3-(n-dodecyl)uridine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.</p>Fórmula:C21H35FN2O5Cor e Forma:SolidPeso molecular:414.51
