Alquilação de DNA
A alquilação do DNA envolve a adição de grupos alquila à molécula de DNA, levando à formação de lesões que podem interferir na replicação e transcrição do DNA. Agentes alquilantes de DNA são comumente usados na quimioterapia do câncer para induzir danos ao DNA em células de rápida divisão. No entanto, as células têm mecanismos para reparar essas lesões, e inibidores das vias de reparo da alquilação do DNA podem aumentar a eficácia dos agentes alquilantes. Na CymitQuimica, oferecemos uma seleção de reagentes e inibidores de alquilação do DNA de alta qualidade para apoiar sua pesquisa em danos ao DNA, mecanismos de reparo e terapia do câncer.
Foram encontrados 21 produtos para "Alquilação de DNA".
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Chlorambucil
CAS:Chlorambucil (CB-1348) is an orally-active antineoplastic aromatic nitrogen mustard.Fórmula:C14H19Cl2NO2Pureza:97.37% - 98.45%Cor e Forma:Off-White Slightly Granular Powder Melting Point 65-69°CPeso molecular:304.21Methyl methanesulfonate
CAS:Methyl methanesulfonate alkylates adenine and guanine, causing base mismatches and replication issues.Fórmula:C2H6O3SPureza:99.69%Cor e Forma:SolidPeso molecular:110.13Altretamine
CAS:Altretamine (ENT-50852) is an alkylating agent with antineoplastic activity.Fórmula:C9H18N6Pureza:99.54%Cor e Forma:White SolidPeso molecular:210.28Melphalan
CAS:Melphalan is an orally bioavailable DNA alkylating agent exhibiting antitumour activity, commonly employed in cancer chemotherapy.Fórmula:C13H18Cl2N2O2Cor e Forma:SolidPeso molecular:305.21N-Ethyl-N-nitrosourea
CAS:N-Ethyl-N-nitrosourea (ENU) is a DNA alkylating agent that damages DNA, inducing bone marrow suppression, leukemia, tumorigenesis, and genetic disorders.Fórmula:C3H7N3O2Pureza:99.97%Cor e Forma:White SolidPeso molecular:117.11Phosphoramide mustard
CAS:Phosphoramide mustard is a toxic metabolite of cyclophosphamide with anticancer activity and ovarian toxicity that induces DNA damage.Fórmula:C4H11Cl2N2O2PPureza:93.00%Cor e Forma:SolidPeso molecular:221.02Methyl methanesulfonate (Standard)
CAS:Methyl methanesulfonate (Standard) is a standard material used in the analysis of methyl methanesulfonate, typically referenced in its research and analysis.Fórmula:C2H6O3SCor e Forma:SolidPeso molecular:110.13Phosphoramide mustard cyclohexanamine
CAS:Phosphoramide mustard cyclohexanamine is active metabolite of cyclophosphamide, an alkylating agent that cross-links DNA strands,causes cell death, antitumor.Fórmula:C10H24Cl2N3O2PPureza:95%Cor e Forma:SolidPeso molecular:320.20VAL-083
CAS:VAL-083 (Dianhydrogalactitol) is an alkylating compound that creates N7 methylation on DNA. It also has antitumor activity.Fórmula:C6H10O4Pureza:97.94%Cor e Forma:SolidPeso molecular:146.14Palifosfamide
CAS:Palifosfamide lysine (ZIO-201) stable, effective vs. sarcomas in vitro. IC50: 2.25-6.75 μM, except OS222 at 31.5 μM.Fórmula:C4H11Cl2N2O2PPureza:99.72%Cor e Forma:SolidPeso molecular:221.02Tretazicar
CAS:CB1954, an anticancer prodrug, turns into a potent alkylating agent when activated by NQO2 and EP-0152R.Fórmula:C9H8N4O5Pureza:99.41% - 99.7%Cor e Forma:White SolidPeso molecular:252.18GNE-3511
CAS:GNE-3511 is a potent and selective dual leucine zipper kinase inhibitors.Fórmula:C23H26F2N6OPureza:98.3% - 99.51%Cor e Forma:SolidPeso molecular:440.49Treosulfan
CAS:Treosulfan (NSC 39069) is a bifunctional alkylating agent used in the treatment of advanced ovarian cancer.Cost-effective and quality-assured.Fórmula:C6H14O8S2Pureza:99.26% - 99.75%Cor e Forma:SolidPeso molecular:278.3Ref: TM-T17159
5mg37,00€1mL*10mM (DMSO)42,00€10mg55,00€25mg100,00€50mg173,00€100mg309,00€200mg432,00€Carmustine
CAS:Carmustine (bis-chloroethylnitrosourea) is a cell-cycle phase nonspecific alkylating antineoplastic agent.Fórmula:C5H9Cl2N3O2Pureza:98% - 99.97%Cor e Forma:Light Yellow Powder Physical Description Orange-Yellow Solid (Ntp 1992)Peso molecular:214.05Lomeguatrib
CAS:Lomeguatrib (PaTrin-2), a modified guanine base, inhibits the activity of DNA repair protein O(6)-alkylguanine-DNA alkyltransferase (MGMT) .Fórmula:C10H8BrN5OSPureza:99.26% - >99.99%Cor e Forma:SolidPeso molecular:326.17Satraplatin
CAS:Satraplatin (BMS182751) is an orally available antineoplastic platinum(IV) complex.Satraplatin has a favorable toxicity profile and appears to have clinicalFórmula:C10H22Cl2N2O4PtPureza:98.25%Cor e Forma:SolidPeso molecular:500.28Ref: TM-T7221
1mgA consultar5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultarMiriplatin hydrate
CAS:Miriplatin hydrate (SM-11355 (hydrate)) (MPT) is a novel platinum complex used in TACE that shows promise for the treatment of hepatocellular carcinoma (HCC).Fórmula:C34H70N2O5PtPureza:99.6%Cor e Forma:White SolidPeso molecular:782.01DN-1289
DN-1289: oral, BBB-penetrating, selectively inhibits DLK (IC50=17nM) & LZK (IC50=40nM), blocks p-c-Jun in mouse optic nerve crush.Fórmula:C18H19F4N7O2Pureza:99.03%Cor e Forma:SolidPeso molecular:441.38GNE-8505
CAS:GNE-8505 is an orally available inhibitor of Dual leucine zipper kinase (DLK).Fórmula:C21H24F3N5OCor e Forma:SolidPeso molecular:419.44IACS-52825
CAS:IACS-52825 is a DLK inhibitor that reverses para-mechanical aberrant pain in a CIPN mouse model and can be used to study neurological disorders.Fórmula:C16H13F7N4O2Pureza:99.77%Cor e Forma:SolidPeso molecular:426.29
