Somatostatina
A somatostatina é um hormônio peptídico que inibe a liberação de vários outros hormônios, incluindo hormônio do crescimento, insulina e glucagon. Atua ligando-se aos receptores de somatostatina, que são receptores acoplados à proteína G expressos em vários tecidos. Análogos da somatostatina são usados no tratamento de acromegalia, tumores neuroendócrinos e distúrbios gastrointestinais. Esses análogos também são ferramentas valiosas para o estudo da secreção hormonal e sinalização. Na CymitQuimica, oferecemos uma gama abrangente de análogos da somatostatina de alta qualidade para apoiar sua pesquisa em endocrinologia, regulação hormonal e desenvolvimento terapêutico.
Foram encontrados 49 produtos de "Somatostatina"
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(1R,5S,6r)-N-(2-methyl-1-((3-methylpyridin-2-yl)oxy)propan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide L(+)-Tartaric acid
CAS:<p>(1R,5S,6r)-N-(2-methyl-1-((3-methylpyridin-2-yl)oxy)propan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide L(+)-Tartaric acid is a potential SSTR4 agonist.</p>Fórmula:C20H29N3O8Pureza:99.72%Cor e Forma:SoildPeso molecular:439.46Somatostatin acetate
<p>Somatostatin acetate is an endogenously secreted inhibitor of cell proliferation with potential antitumor activity for the study of cancer and neurological disorders.</p>Pureza:99.11%Cor e Forma:Odour SolidCortistatin 14, human, rat acetate
<p>Cortistatin 14, human, rat acetate is a neuropeptide having structural similarity to somatostatin-14 and shows anticonvulsive, neuroprotective effects and</p>Fórmula:C80H112N18O19S2Pureza:97.86%Cor e Forma:SolidPeso molecular:1693.98Cortistatin-14 acetate
<p>Cortistatin-14 acetate, a neuropeptide have structural similarity to somatostatin-14, binds and exerts its function via the somatostatin receptors (sst1-sst5).</p>Fórmula:C83H118N20O20S2Pureza:98.24% - 99.63%Cor e Forma:SoildPeso molecular:1780.08Seglitide acetate
CAS:<p>Seglitide acetate (MK-678) is a selective agonist of sst2 somatostatin receptor.</p>Fórmula:C46H60N8O9Pureza:98.87%Cor e Forma:SolidPeso molecular:869.02Cyclosomatostatin Acetate
<p>Cyclosomatostatin Acetate is an effective antagonist of the somatostatin receptor.Cyclosomatostatin Acetate inhibits SSTR1 signaling and decreases cell</p>Fórmula:C46H61N7O8Pureza:98.83%Cor e Forma:SolidPeso molecular:840.02Seglitide
CAS:<p>Peptide agonist targets sst2/sst5 receptors. IC50/Kd: sst1 >1000, sst2 = 0.2-1.5, sst3 = 27-36, sst4 >127, sst5 = 0.06-23 nM.</p>Fórmula:C44H56N8O7Pureza:98%Cor e Forma:SolidPeso molecular:808.98Ilatreotide
CAS:<p>Ilatreotide is a Amadori compound of octreotide.</p>Fórmula:C61H86N10O20S2Pureza:98%Cor e Forma:SolidPeso molecular:1343.53CYN 154806
CAS:<p>CYN 154806: potent sst2 antagonist; pIC50: 8.58 (sst2), 5.41 (sst1), 6.07 (sst3), 5.76 (sst4), 6.48 (sst5).</p>Fórmula:C56H68N12O14S2Pureza:98%Cor e Forma:SolidPeso molecular:1197.34Cortistatin 14, human, rat
CAS:<p>Cortistatin 14: a neuropeptide similar to somatostatin; induces sleep, depresses neuronal activity; found in cortex, hippocampus.</p>Fórmula:C81H113N19O19S2Pureza:98%Cor e Forma:SolidPeso molecular:1721.01Veldoreotide
CAS:Veldoreotide (Somatoprim): a somatostatin analogue targeting receptors 2, 4, 5, reduces GH in pituitary adenomas.Fórmula:C60H74N12O10Pureza:98%Cor e Forma:SolidPeso molecular:1123.3Somatostatin(3-6)
CAS:<p>Somatostatin(3-6) is a somatostatin fragment.</p>Fórmula:C22H34N6O6SCor e Forma:SolidPeso molecular:510.61MMC(TMZ)-TOC TFA
<p>MMC(TMZ)-TOC TFA exhibits high binding affinity and selectivity for the somatostatin receptor subtype 2 (SSTR2). It targets the delivery of TMZ to SSTR2-positive tumor cells, making MMC(TMZ)-TOC TFA useful for cancer research.</p>Fórmula:C74H99F3N20O21S2Cor e Forma:SolidPeso molecular:1725.82Cortistatin 29
<p>Cortistatin 29: neuropeptide, relieves neuropathic pain, binds SS receptors (IC50: 2.8-13.7 nM), anti-fibrotic.</p>Fórmula:C161H242N46O41S2Cor e Forma:SolidPeso molecular:3539.77Satoreotide
CAS:<p>Satoreotide (JR11) is an SSTR2 antagonist, typically conjugated with radiolabeled chelators for use in neuroendocrine tumor imaging [1].</p>Fórmula:C58H72ClN15O14S2Cor e Forma:SolidPeso molecular:1302.87L-796,778
CAS:<p>L-796,778 is an SST3 agonist and a selective ligand of SST3, which can increase the level of cAMP in the body.</p>Fórmula:C29H40N6O7Pureza:96.20%Cor e Forma:SolidPeso molecular:584.66BIM-23190 hydrochloride
<p>BIM-23190 hydrochloride, somatostatin analog, SSRT2/5 agonist, Ki: 0.34 nM (SSTR2), 11.1 nM (SSTR5). Used in cancer, acromegaly research.</p>Cor e Forma:LiquidDOTA-JR11
CAS:<p>DOTA-JR11 is a somatostatin receptor 2 (SSTR2) antagonist that can be radiolabeled with 68Ga.</p>Fórmula:C74H98ClN19O21S2Cor e Forma:SolidPeso molecular:1689.27Dotanoc
CAS:<p>Dotanoc is a ligand to make gallium Ga 68-DOTANOC, which is a gallium Ga 68-radiolabeled analog of somatostatin.</p>Fórmula:C69H94N14O17S2Cor e Forma:SolidPeso molecular:1455.71Cyclic SSTR agonist octreotide
<p>Cyclic SSTR agonist octreotide is a Octreotide , serving as the cyclic Somatostatin Receptor SSTR agonist [1] .</p>Fórmula:C53H71N11O14S2Cor e Forma:SolidPeso molecular:1150.33Cyclosomatostatin TFA
<p>Cyclosomatostatin TFA blocks SST receptor, reduces CRC cell growth, ALDH+ size, and sphere-formation.</p>Fórmula:C46H58F3N7O8Cor e Forma:SolidPeso molecular:893.99L-796,778 acetate
<p>L-796,778 acetate is a slective somatostatin receptor agonist with IC50 of 24nM for sst3, for sst1, sst2, sst4 and sst5, IC50 is >1000nM.</p>Fórmula:C31H44N6O9Pureza:98%Cor e Forma:SoildPeso molecular:644.72Tau conotoxin CnVA
CAS:<p>Tau conotoxin CnVA, a small peptide found in the venom of Conus consors (cone snail), is a member of the T1 cone snail peptide superfamily. It demonstrates high selectivity for the somatostatin sst3 receptor with a Ki value of 1.5 µM. Tau conotoxin CnVA is unique as the only known toxin interacting with this subfamily of G protein-coupled receptors (GPCR). This compound is useful for research related to diseases associated with the sst3 receptor, such as pancreatic cancer or pituitary adenomas.</p>Fórmula:C72H116N24O17S4Cor e Forma:SolidPeso molecular:1718.1SSTR4 agonist-1
CAS:<p>SSTR4agonist-1 (Compound 47) is a selective agonist of the somatostatin receptor 4 (SSTR4), with an EC50 of 4.7 nM. It has a half-life of over 130 minutes in human liver microsomes.</p>Fórmula:C16H23N3O2Cor e Forma:SolidPeso molecular:289.37L-797,591 hydrochloride
<p>L-797,591 HCl activates SSTR1, boosts p-ERK5 with AG1478, and enhances p38 phosphorylation, reversible by AG1478.</p>Fórmula:C38H50ClN5O2Pureza:98.65% - >99.99%Cor e Forma:SoildPeso molecular:644.30Somatostatin-28 (1-14)
CAS:<p>Somatostatin-28 (1-14) is a truncated neuropeptide from prosomatostatin cleavage.</p>Fórmula:C61H105N23O21SPureza:98%Cor e Forma:SolidPeso molecular:1528.71CH 275
CAS:<p>Potent sst1 agonist with 30.9 nM IC50; selective over sst2-5; inhibits somatostatin in rat nucleus accumbens.</p>Fórmula:C74H96N14O15S2Pureza:98%Cor e Forma:SolidPeso molecular:1485.8Somatostatin 1-28 acetate
<p>Somatostatin 1-28 acetate circulates in human plasma.</p>Pureza:99.22%Cor e Forma:SoildSomatostatin
CAS:<p>Somatostatin: a peptide hormone inhibiting growth hormone, insulin, and glucagon; secreted by hypothalamus and pancreatic D cells.</p>Pureza:98%Cor e Forma:PowderPeso molecular:1637.88Neuronostatin-13 (human)
CAS:<p>Neuronostatin-13: human-conserved, 13-amino-acid peptide with amidated C-terminus.</p>Fórmula:C64H110N20O16Pureza:98%Cor e Forma:SolidPeso molecular:1415.68[D-Trp8,Tyr11] Somatostatin
CAS:[D-Trp8,Tyr11] Somatostatin, an analogue of the hormone somatostatin that modulates numerous bodily functions, is characterized by the substitution of DTrp8,Fórmula:C76H104N18O20S2Peso molecular:1653.88[Tyr11]-Somatostatin
CAS:[Tyr11]-Somatostatin, a neuroactive peptide, aids proteomics research and modulates retinal function.Fórmula:C76H104N18O20S2Peso molecular:1653.89DOTA-EB-TATE
DOTA-EB-TATE is formed by combining the SST peptide derivative DOTA-octreotate with an Evans blue analog (EB). This peptide drug conjugate (PDC) enhances the pharmacokinetics of SSTR2 analogs and reduces PRRT toxicity. Additionally, DOTA-EB-TATE serves in the synthesis/research of radiopharmaceutical conjugates (RDC).Fórmula:C105H133N21O30S5Peso molecular:2329.63Cortistatin-14
CAS:<p>Cortistatin-14, a neuropeptide structurally similar to growth inhibitor-14, is used to study sepsis-induced cognitive impairment.</p>Fórmula:C81H114N20O18S2Pureza:98.06% - 98.23%Cor e Forma:SolidPeso molecular:1720.03Lanreotide
CAS:Lanreotide, a somatostatin analogue, suppresses GH/IGF-I hypersecretion in acromegaly patients. It also used to manage neuroendocrine tumours.Fórmula:C54H69N11O10S2Cor e Forma:SolidPeso molecular:1096.32Anti-Somatostatin Antibody (9L93)
<p>Anti-Somatostatin Antibody (9L93) is a Rabbit antibody targeting Somatostatin. Anti-Somatostatin Antibody (9L93) can be used in ELISA.</p>Cor e Forma:Odour LiquidBIM-23190 aceate
<p>BIM-23190 aceate, a somatostatin analog, a selective agonist of SSTR2 and SSTR5. BIM-23190 can be used in cancer and acromegaly studies.</p>Fórmula:C59H83N13O14S2Pureza:99.7%Cor e Forma:SolidPeso molecular:1262.5Paltusotine
CAS:<p>Paltusotine: nonpeptide SST2 agonist, orally bioavailable, regulates GH/IGF-1 in acromegaly.</p>Fórmula:C27H22F2N4OPureza:99.91%Cor e Forma:SolidPeso molecular:456.49Pasireotide Acetate
CAS:<p>The pKi of Pasireotide (SOM230) acetate for sst1, 2, 3, 4, and 5 were 8.2, 9.0, 9.1, less than 7.0, and 9.9, respectively.Cost-effective and quality-assured.</p>Fórmula:C60H70N10O11Pureza:98.64% - 99.92%Cor e Forma:SolidPeso molecular:1107.26Octreotide Acetate
CAS:<p>Octreotide Acetate (Sandostatin) is a potent, long-acting synthetic somatostatin octapeptide analog that inhibits secretion of growth hormone.</p>Fórmula:C51H70N10O12S2Pureza:99.03% - 99.87%Cor e Forma:Less To Off-White Lyophilised Solid Colourless To Off-White Lyophilised SolidPeso molecular:1079.3FK962
CAS:<p>FK962 is an somatostatin release enhancer , exerts cognitive-enhancing actions.</p>Fórmula:C14H17FN2O2Pureza:99.89%Cor e Forma:SolidPeso molecular:264.3Somatostatin Impurity 2 (13-Dha) Trifluoroacetate
Fórmula:C76H102N18O18S2·C2HF3O2Peso molecular:1619.88 114.02CYN 154806 TFA
CAS:<p>CYN 154806 TFA: cyclic octapeptide, selective somatostatin sst2 antagonist; pIC50: sst2 - 8.58, sst1 - 5.41, sst3 - 6.07, sst4 - 5.76, sst5 - 6.48.</p>Fórmula:C58H69F3N12O16S2Pureza:99.7%Cor e Forma:SolidPeso molecular:1311.36Edotreotide
CAS:<p>Edotreotide (SMT-487) is an Indicator and Reagent. It also is used in the Diagnosis and Staging of Tumors Expressing Somatostatin Receptors.</p>Fórmula:C65H92N14O18S2Pureza:96.95%Cor e Forma:SolidPeso molecular:1421.64L-803087
CAS:<p>L-803087: potent sst4 receptor agonist, 0.7 nM Ki, 280x selectivity, boosts AMPA responses & seizures in mice.</p>Fórmula:C25H29F2N5O3Pureza:97.58%Cor e Forma:SolidPeso molecular:485.53L-796778 acetate
CAS:<p>L-796778 acetate is a selective sst3 receptor agonist. In CHO-K1 cells expressing hsst3 receptors, it acts as a partial agonist that inhibits Forskolin-induced cAMP production, with an IC50 value of 18 nM. Additionally, L-796778 acetate exhibits anticonvulsant properties.</p>Fórmula:C31H44N6O9Cor e Forma:SolidPeso molecular:644.716SSTR5 antagonist 6
CAS:<p>SSTR5 antagonist 6, an orally active antagonist specific to the somatostatin receptor subtype 5 (SSTR5), exhibits an IC50 value of 24 nM. This compound is utilized in researching type 2 diabetes [1].</p>Fórmula:C22H28ClN3O4Cor e Forma:SolidPeso molecular:433.93
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