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Somatostatina

Somatostatina

A somatostatina é um hormônio peptídico que inibe a liberação de vários outros hormônios, incluindo hormônio do crescimento, insulina e glucagon. Atua ligando-se aos receptores de somatostatina, que são receptores acoplados à proteína G expressos em vários tecidos. Análogos da somatostatina são usados no tratamento de acromegalia, tumores neuroendócrinos e distúrbios gastrointestinais. Esses análogos também são ferramentas valiosas para o estudo da secreção hormonal e sinalização. Na CymitQuimica, oferecemos uma gama abrangente de análogos da somatostatina de alta qualidade para apoiar sua pesquisa em endocrinologia, regulação hormonal e desenvolvimento terapêutico.

Foram encontrados 49 produtos de "Somatostatina"

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  • Cyclosomatostatin TFA


    <p>Cyclosomatostatin TFA blocks SST receptor, reduces CRC cell growth, ALDH+ size, and sphere-formation.</p>
    Fórmula:C46H58F3N7O8
    Cor e Forma:Solid
    Peso molecular:893.99
  • L-796,778 acetate


    <p>L-796,778 acetate is a slective somatostatin receptor agonist with IC50 of 24nM for sst3, for sst1, sst2, sst4 and sst5, IC50 is &gt;1000nM.</p>
    Fórmula:C31H44N6O9
    Pureza:98%
    Cor e Forma:Soild
    Peso molecular:644.72
  • Tau conotoxin CnVA

    CAS:
    <p>Tau conotoxin CnVA, a small peptide found in the venom of Conus consors (cone snail), is a member of the T1 cone snail peptide superfamily. It demonstrates high selectivity for the somatostatin sst3 receptor with a Ki value of 1.5 µM. Tau conotoxin CnVA is unique as the only known toxin interacting with this subfamily of G protein-coupled receptors (GPCR). This compound is useful for research related to diseases associated with the sst3 receptor, such as pancreatic cancer or pituitary adenomas.</p>
    Fórmula:C72H116N24O17S4
    Cor e Forma:Solid
    Peso molecular:1718.1
  • SSTR4 agonist-1

    CAS:
    <p>SSTR4agonist-1 (Compound 47) is a selective agonist of the somatostatin receptor 4 (SSTR4), with an EC50 of 4.7 nM. It has a half-life of over 130 minutes in human liver microsomes.</p>
    Fórmula:C16H23N3O2
    Cor e Forma:Solid
    Peso molecular:289.37
  • Somatostatin Diacetate

    CAS:
    Fórmula:C76H104N18O19S2·2C2H4O2
    Peso molecular:1637.90 2*60.05

    Ref: 4Z-PS-219001

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  • L-797,591 hydrochloride


    <p>L-797,591 HCl activates SSTR1, boosts p-ERK5 with AG1478, and enhances p38 phosphorylation, reversible by AG1478.</p>
    Fórmula:C38H50ClN5O2
    Pureza:98.65% - >99.99%
    Cor e Forma:Soild
    Peso molecular:644.30
  • Somatostatin-28 (1-14)

    CAS:
    <p>Somatostatin-28 (1-14) is a truncated neuropeptide from prosomatostatin cleavage.</p>
    Fórmula:C61H105N23O21S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1528.71
  • CH 275

    CAS:
    <p>Potent sst1 agonist with 30.9 nM IC50; selective over sst2-5; inhibits somatostatin in rat nucleus accumbens.</p>
    Fórmula:C74H96N14O15S2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1485.8
  • Somatostatin 1-28 acetate


    <p>Somatostatin 1-28 acetate circulates in human plasma.</p>
    Pureza:99.22%
    Cor e Forma:Soild
  • Somatostatin

    CAS:
    <p>Somatostatin: a peptide hormone inhibiting growth hormone, insulin, and glucagon; secreted by hypothalamus and pancreatic D cells.</p>
    Pureza:98%
    Cor e Forma:Powder
    Peso molecular:1637.88
  • Neuronostatin-13 (human)

    CAS:
    <p>Neuronostatin-13: human-conserved, 13-amino-acid peptide with amidated C-terminus.</p>
    Fórmula:C64H110N20O16
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1415.68
  • [D-Trp8,Tyr11] Somatostatin

    CAS:
    [D-Trp8,Tyr11] Somatostatin, an analogue of the hormone somatostatin that modulates numerous bodily functions, is characterized by the substitution of DTrp8,
    Fórmula:C76H104N18O20S2
    Peso molecular:1653.88
  • [Tyr11]-Somatostatin

    CAS:
    [Tyr11]-Somatostatin, a neuroactive peptide, aids proteomics research and modulates retinal function.
    Fórmula:C76H104N18O20S2
    Peso molecular:1653.89
  • DOTA-EB-TATE


    DOTA-EB-TATE is formed by combining the SST peptide derivative DOTA-octreotate with an Evans blue analog (EB). This peptide drug conjugate (PDC) enhances the pharmacokinetics of SSTR2 analogs and reduces PRRT toxicity. Additionally, DOTA-EB-TATE serves in the synthesis/research of radiopharmaceutical conjugates (RDC).
    Fórmula:C105H133N21O30S5
    Peso molecular:2329.63
  • Cortistatin-14

    CAS:
    <p>Cortistatin-14, a neuropeptide structurally similar to growth inhibitor-14, is used to study sepsis-induced cognitive impairment.</p>
    Fórmula:C81H114N20O18S2
    Pureza:98.06% - 98.23%
    Cor e Forma:Solid
    Peso molecular:1720.03
  • Lanreotide

    CAS:
    Lanreotide, a somatostatin analogue, suppresses GH/IGF-I hypersecretion in acromegaly patients. It also used to manage neuroendocrine tumours.
    Fórmula:C54H69N11O10S2
    Cor e Forma:Solid
    Peso molecular:1096.32
  • Anti-Somatostatin Antibody (9L93)


    <p>Anti-Somatostatin Antibody (9L93) is a Rabbit antibody targeting Somatostatin. Anti-Somatostatin Antibody (9L93) can be used in ELISA.</p>
    Cor e Forma:Odour Liquid
  • BIM-23190 aceate


    <p>BIM-23190 aceate, a somatostatin analog, a selective agonist of SSTR2 and SSTR5. BIM-23190 can be used in cancer and acromegaly studies.</p>
    Fórmula:C59H83N13O14S2
    Pureza:99.7%
    Cor e Forma:Solid
    Peso molecular:1262.5
  • Paltusotine

    CAS:
    <p>Paltusotine: nonpeptide SST2 agonist, orally bioavailable, regulates GH/IGF-1 in acromegaly.</p>
    Fórmula:C27H22F2N4O
    Pureza:99.91%
    Cor e Forma:Solid
    Peso molecular:456.49
  • Pasireotide Acetate

    CAS:
    <p>The pKi of Pasireotide (SOM230) acetate for sst1, 2, 3, 4, and 5 were 8.2, 9.0, 9.1, less than 7.0, and 9.9, respectively.Cost-effective and quality-assured.</p>
    Fórmula:C60H70N10O11
    Pureza:98.64% - 99.92%
    Cor e Forma:Solid
    Peso molecular:1107.26