Receptor de hormónio tireoidiano (THR)
Os receptores de hormônio tireoidiano (THR) são receptores nucleares que mediam os efeitos dos hormônios tireoidianos, que são críticos para a regulação do metabolismo, crescimento e desenvolvimento. A modulação da atividade dos THR é importante no tratamento de distúrbios da tireoide, síndromes metabólicas e certos tipos de câncer. Agonistas e antagonistas de THR são usados em pesquisas para estudar os papéis fisiológicos e patológicos dos hormônios tireoidianos. Na CymitQuimica, oferecemos uma ampla gama de moduladores de receptores de hormônio tireoidiano de alta qualidade para apoiar sua pesquisa em endocrinologia, metabolismo e regulação hormonal.
Foram encontrados 34 produtos de "Receptor de hormónio tireoidiano (THR)"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
PCO371
CAS:PCO371 (2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-Fórmula:C29H32F3N5O6SPureza:97.17% - 99.25%Cor e Forma:SolidPeso molecular:635.65Ref: TM-T16442
1mg63,00€5mg137,00€1mL*10mM (DMSO)178,00€10mg197,00€25mg356,00€50mg505,00€100mg715,00€3,5-Diiodothyropropionic acid
CAS:3,5-Diiodothyropropionic acid: thyroid hormone analog, boosts α-myosin mRNA, binds TRα1 & TRβ1 (Ka: 2.40/M, 4.06/M).Fórmula:C15H12I2O4Pureza:98.42%Cor e Forma:SolidPeso molecular:510.06Human PTHrP-(1-36)
CAS:Human PTHrP-(1-36) is a secreted form of parathyroid hormone-related protein that exhibits anticalciuric effects and promotes beta cell function andFórmula:C191H305N59O52Cor e Forma:SolidPeso molecular:4259.83Parathyroid Hormone (1-34), bovine
CAS:Parathyroid Hormone (1-34), bovine is a PTH receptor agonist used to study osteoporosis and hypoparathyroidism.Fórmula:C183H288N54O50S2Pureza:99.72%Cor e Forma:SolidPeso molecular:4104.39NH-3
CAS:NH-3, an orally active THR antagonist with a 55 nM IC50, blocks thyroid hormone binding and cofactor recruitment.Fórmula:C28H27NO6Pureza:97.79% - 99.40%Cor e Forma:SolidPeso molecular:473.52Ref: TM-T40548
1mg207,00€1mL*10mM (DMSO)467,00€5mg520,00€10mg750,00€25mg1.144,00€50mg1.521,00€100mg2.062,00€500mg4.159,00€Parathyroid hormone (1-34) (rat)
CAS:Parathyroid hormone (PTH) receptor agonist. Increases serum PTH levels and bone mass in rats.Fórmula:C180H291N55O48S2Pureza:98%Cor e Forma:SolidPeso molecular:4057.74DPC-AJ1951
CAS:Potent 14 amino acid peptide agonist of the parathyroid hormone (PTH) receptor (EC50 = 26 nM).Fórmula:C76H127N23O19Pureza:98%Cor e Forma:SolidPeso molecular:1666.98pTH (1-37) (human)
CAS:pTH (1-37) human fragment boosts cAMP, alkaline phosphatase, growth, and BMD, potential for osteoporosis research.Fórmula:C195H316N58O54S2Cor e Forma:SolidPeso molecular:4401.08Prepro-TRH-(160-169)
CAS:Prepro-TRH-(160-169), a pro-TRH peptide, enhances TRH-stimulated TSH secretion.Fórmula:C54H75N11O18SCor e Forma:SolidPeso molecular:1198.3THR-β agonist 2 diacetate
THR-β agonist 2 diacetate (Compound 3) is a potent THR-β agonist with potential applications in researching metabolic disorders such as obesity, hyperlipidemia, hypercholesterolemia, and diabetes, as well as other conditions like steatosis and non-alcoholic steatohepatitis (NASH), atherosclerosis, and other related diseases and conditions.Cor e Forma:Odour SolidOsteostatin (1-5) amide (human, bovine, dog, horse, mouse, rabbit, rat)
CAS:Osteostatin (1-5) amide (human, bovine, dog, horse, mouse, rabbit, rat), also known as Human PTHrP (107-111) amide, is a C-terminal fragment of parathyroidFórmula:C27H42N10O7Peso molecular:618.69Osteostatin
CAS:Osteostatin, derived from parathyroid hormone-related protein (PTHrP) 107-111, has demonstrated properties conducive to bone repair in animal models presentingFórmula:C27H41N9O8Cor e Forma:SolidPeso molecular:619.67DPC-AJ1951 TFA
DPC-AJ1951 TFA is a 14 amino acid peptide, potent PTH/PPR agonist, tested in bone resorption assays.Fórmula:C78H128F3N23O21Cor e Forma:SolidPeso molecular:1781.02Human PTH-(1-31) amide
CAS:Human PTH-(1-31) amide, an analog of PTH, effectively stimulates phosphatidylcholine hydrolysis and promotes the release of adenylyl cyclase [1].Fórmula:C162H270N50O46S2Cor e Forma:SolidPeso molecular:3718.31Trh-gly
CAS:TRH-glycine (TRH-gly) serves as a precursor to thyrotropin-releasing hormone (TRH), capable of inducing the release of thyrotropin (TSH) and prolactin [1].Fórmula:C18H24N6O6Cor e Forma:SolidPeso molecular:420.42(Tyr36)-pTH-Related Protein (1-36) (human, mouse, rat)
CAS:'(Tyr36)-pTH-Related Protein (1-36) (human, mouse, rat), a peptide, functions as a ligand for parathyroid hormone (PTH) receptors [1].'Fórmula:C194H303N59O53Peso molecular:4309.85Calcitonin, eel
CAS:Calcitonin from eel regulates calcium and is key in studying postmenopausal osteoporosis.
Fórmula:C146H241N43O47S2Pureza:98%Cor e Forma:White PowderPeso molecular:3414.91pTH-Related Protein (1-34) amide (human, mouse, rat)
CAS:Human PTHrP-(1-34)NH2, also known as PTH-Related Protein (1-34) amide for human, mouse, and rat, is the N-terminal fragment of PTHrP.Cor e Forma:SolidEprotirome
CAS:Eprotirome (KB2115), a synthetic thyroid hormone mimetic, is a thyroid hormone receptor agonist.Fórmula:C18H17Br2NO5Pureza:98.42% - 98.56%Cor e Forma:SolidPeso molecular:487.14Ref: TM-T5360
2mg34,00€5mg50,00€1mL*10mM (DMSO)52,00€10mg80,00€25mg145,00€50mg222,00€100mg356,00€200mg522,00€REVERSE T3
CAS:Reverse T3 (3,3',5'-triiodo-L-thyronine) inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes.Fórmula:C15H12I3NO4Pureza:95.99% - 97.89%Cor e Forma:PowderPeso molecular:650.97Resmetirom
CAS:Resmetirom (MGL-3196) is a THR-β agonist (EC50=0.21 μM), with high selectivity and oral activity. High-Quality, Low-Cost!Fórmula:C17H12Cl2N6O4Pureza:99.05% - >99.99%Cor e Forma:SolidPeso molecular:435.22Ref: TM-T3595
1mg37,00€2mg49,00€1mL*10mM (DMSO)87,00€5mg93,00€10mg119,00€25mg202,00€50mg324,00€100mg482,00€500mg1.071,00€Sobetirome
CAS:Sobetirome (IACS-010759) is a selective agonist of thyroid hormone receptor β (TRβ) and binds selectively to TRβ-1 (EC50: 0.16 μM).Fórmula:C20H24O4Pureza:98.08% - 98.25%Cor e Forma:SolidPeso molecular:328.4(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate
D-Trp12,Tyr34-pTH(7-34) (bovine) is a PTH antagonist with a Ki of 69 nM in bovine kidneys.Pureza:96.84%Cor e Forma:LiquidPeso molecular:N/ADPC AJ1951 acetate
DPC-AJ1951 acetate: 14-amino acid peptide, potent PTH/PPR agonist, tested for bone resorption activity ex vivo/in vivo.Fórmula:C78H131N23O21Pureza:96.63%Cor e Forma:SolidPeso molecular:1727.023,3',5-Triiodothyronine-(tyrosine ring-13C6)
CAS:3,3',5-Triiodothyronine-(tyrosine ring-13C6) is the 13C labeled compound of 3,3',5-Triiodothyronine. 3,3',5-Triiodothyronine has a CAS number of 5817-39-0.
Fórmula:C4C11H12I3NO4Cor e Forma:SolidPeso molecular:656.93KAT681
CAS:KAT681 is a liver selective thyromimetic.Fórmula:C24H22FNNaO6Pureza:98%Cor e Forma:SolidPeso molecular:462.429Azetirelin
CAS:Azetirelin, as a TRH analog, has a more potent effect than TRH on the central nervous system.Fórmula:C15H20N6O4Pureza:99.72%Cor e Forma:SolidPeso molecular:348.36Glutaurine aceate
Glutaurine aceate containing glutamine and taurine residues is an orally active hormone of the parathyroid.Fórmula:C9H18N2O8SPureza:98%Cor e Forma:SoildPeso molecular:314.31TR antagonist 1
CAS:TR antagonist 1 is a highly potent thyroid hormone receptor (TR) antagonist that can be used to study diseases caused by endocrine abnormalities.Fórmula:C25H23Br2NO4Pureza:99.57%Cor e Forma:SolidPeso molecular:561.26MB-07344
CAS:MB-07344 is a selective THR-β (thyroid hormone receptor β) agonist with a Ki of 2.17 nM, capable of reducing plasma total cholesterol (TPC).Fórmula:C19H25O5PPureza:99.32%Cor e Forma:SolidPeso molecular:364.37CO23
CAS:CO23 is a blood-brain barrier penetrant and selective TRα agonist and can be used in studies about the regulation of growth and development.Fórmula:C19H18I2N2O4Pureza:98.08%Cor e Forma:SolidPeso molecular:592.17DS08210767
CAS:DS08210767 is a highly potent, orally bioavailable PTHR1 antagonist with IC50 of 90 nM.Fórmula:C31H39N5O2Pureza:98.79%Cor e Forma:SolidPeso molecular:513.67MB-07811
CAS:MB-07811 (VK-2809) is an orally active HepDirect prodrug of MB07344 with cholesterol and triglycerides lowering activity.Fórmula:C28H32ClO5PPureza:99.74% - 99.94%Cor e Forma:SolidPeso molecular:514.98MLS000389544
CAS:MLS000389544 is a selective and potent thyroid hormone receptor β (TRβ) antagonist with a methylsulfonyl nitrobenzoic acid structure. It effectively inhibits the interaction between TRβ and steroid receptor coactivator 2 (SRC2).Fórmula:C20H24N2O7SCor e Forma:SolidPeso molecular:436.479
