Receptor de Androgénio
O receptor de andrógenos (AR) é um receptor hormonal nuclear que é ativado pela ligação a andrógenos, como a testosterona e a diidrotestosterona. Este receptor desempenha um papel crucial no desenvolvimento e na manutenção das características masculinas, bem como na regulação de vários processos fisiológicos, incluindo o crescimento muscular, a libido e a densidade óssea. Inibidores do receptor de andrógenos são amplamente estudados no contexto do câncer de próstata, onde a sinalização do AR é frequentemente aumentada. Na CymitQuimica, oferecemos uma gama de moduladores do receptor de andrógenos de alta qualidade para apoiar sua pesquisa em endocrinologia, biologia do câncer e regulação hormonal.
Foram encontrados 207 produtos de "Receptor de Androgénio"
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AR antagonist 2
CAS:<p>AR antagonist 2 (compound 58) is a potent inhibitor of the androgen receptor (AR) (IC50: 0.95 μM).</p>Fórmula:C22H17ClFN5O2SCor e Forma:SolidPeso molecular:469.92AR antagonist 5
CAS:<p>Compound 30a, known as AR Antagonist 5, is a selective androgen receptor (AR) antagonist that demonstrates an IC 50 value of 134.8 nM. It exhibits favorable pharmacokinetic properties, characterized by high skin exposure and low plasma exposure [1].</p>Fórmula:C23H21F3N6O2Cor e Forma:SolidPeso molecular:470.45CSRM617
CAS:<p>CSRM617: selective ONECUT2 inhibitor, Kd 7.43 uM, binds OC2-HOX, induces apoptosis, tolerable in mouse prostate cancer model.</p>Fórmula:C10H13N3O5Pureza:98%Cor e Forma:SolidPeso molecular:255.23MK-4541
CAS:<p>MK-4541: oral, selective AR modulator, blocks 5α-reductase, curbs AR+ prostate cancer growth, effective in mouse model.</p>Fórmula:C22H31F3N2O3Cor e Forma:SolidPeso molecular:428.49(R)-UT-155
CAS:<p>(R)-UT-155 is a selective androgen receptor degrader (SARD) ligand.</p>Fórmula:C20H15F4N3O2Cor e Forma:SolidPeso molecular:405.35Carbazole derivative 1
CAS:<p>Carbazole derivative 1 is used to reduce androgen or oestrogen levels in mammals.</p>Fórmula:C18H13FN2Pureza:98%Cor e Forma:SolidPeso molecular:276.31VPC-3033
CAS:<p>VPC-3033 is an antagonist of the androgen receptor. It acts by inhibiting the LNCaP cell line as well as cell lines with the wild-type androgen receptor.</p>Fórmula:C21H14O2Pureza:98%Cor e Forma:SolidPeso molecular:298.33Androgen receptor antagonist 3
CAS:<p>Androgen receptor antagonist 3 (Compound C18) has anticancer activities that is an antagonist of androgen receptor (AR) (IC 50 = 2.4 μM) [1].</p>Fórmula:C22H18ClNCor e Forma:SolidPeso molecular:331.84RU 58642
CAS:<p>RU 58642 is an effective systemic antiandrogen for androgen-dependent disorders.</p>Fórmula:C15H11F3N4O2Pureza:98%Cor e Forma:SolidPeso molecular:336.27VPC-13789
CAS:<p>VPC-13789: potent, selective oral antiandrogen for CRPC with 0.19 μM IC50 in LNCaP cells.</p>Fórmula:C21H16F3N3OCor e Forma:SolidPeso molecular:383.37Topterone
CAS:<p>Topterone (Win 17,665) is a potent topical antiandrogen that inhibits the stimulation of lumbar organ development by testosterone and dihydrotestosterone in</p>Fórmula:C22H34O2Pureza:>99.99%Cor e Forma:SolidPeso molecular:330.5Ar-V7-IN-1
CAS:<p>Ar-V7-IN-1 (compound 47) is a potent inhibitor of Ar-V7,associated with resistance to AR-targeted therapy with desmoplasia-resistant prostate cancer (mCRPC).</p>Fórmula:C10H10Br2N4OSCor e Forma:SolidPeso molecular:394.09Prochloraz
CAS:<p>Prochloraz: broad-spectrum imidazole fungicide; blocks placental aromatase (IC50=40nM), estrogen/androgen receptors; activates aryl hydrocarbon receptors.</p>Fórmula:C15H16Cl3N3O2Pureza:99.75% - 99.79%Cor e Forma:Colorless SolidPeso molecular:376.67Androgen receptor antagonist 1
CAS:<p>Androgen receptor antagonist 1, an oral full AR antagonist (IC50 59 nM), for PROTAC synthesis, reducing AR protein by 24–47% in LNCaP cells at 1–10 μM.</p>Fórmula:C21H25ClN4O3Pureza:99.054%Cor e Forma:SolidPeso molecular:416.9Bromopropylate
CAS:<p>Bromopropylate is an insecticide. Bromopropylate is the active substance in fumigant strips for mites.</p>Fórmula:C17H16Br2O3Pureza:98%Cor e Forma:White Crystalline Solid Yellowish CrystalsPeso molecular:428.11Dimethomorph
CAS:<p>Dimethomorph is a fungicide and sterol biosynthesis inhibitor that inhibits fungal cell wall formation,. inhibits androgen receptor (AR) .</p>Fórmula:C21H22ClNO4Pureza:99.2%Cor e Forma:Solid CrystallinePeso molecular:387.86MK-3984
CAS:<p>MK-3984 is a selective androgen receptor modulator, used in the study of conditions caused by androgen deficiency.</p>Fórmula:C17H12F7NO2Pureza:99.91%Cor e Forma:SolidPeso molecular:395.27Bifluranol
CAS:<p>Bifluranol (BX341) has anti-androgenic activity and has shown significant anti-prostatic activity in in vivo studies for the treatment of benign prostatic</p>Fórmula:C17H18F2O2Pureza:99.77%Cor e Forma:SolidPeso molecular:292.32VPC-14449
CAS:<p>VPC-14449 is a selective androgen receptor DNA-binding domain (AR-DBD) inhibitor, useful in prostate cancer research.</p>Fórmula:C10H10Br2N4OSPureza:99.56%Cor e Forma:SolidPeso molecular:394.09Ralaniten
CAS:<p>Ralaniten (EPI-002), a potent AR-NTD antagonist, inhibits AR with IC50 of 7.4 μM, for CRPC study.</p>Fórmula:C21H27ClO5Pureza:99.77%Cor e Forma:SolidPeso molecular:394.89
