Receptor de Androgénio
O receptor de andrógenos (AR) é um receptor hormonal nuclear que é ativado pela ligação a andrógenos, como a testosterona e a diidrotestosterona. Este receptor desempenha um papel crucial no desenvolvimento e na manutenção das características masculinas, bem como na regulação de vários processos fisiológicos, incluindo o crescimento muscular, a libido e a densidade óssea. Inibidores do receptor de andrógenos são amplamente estudados no contexto do câncer de próstata, onde a sinalização do AR é frequentemente aumentada. Na CymitQuimica, oferecemos uma gama de moduladores do receptor de andrógenos de alta qualidade para apoiar sua pesquisa em endocrinologia, biologia do câncer e regulação hormonal.
Foram encontrados 207 produtos de "Receptor de Androgénio"
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LGD-2226
CAS:<p>LGD-2226: selective oral androgen receptor modulator, EC50: 0.2nM, Ki: 1.5nM. Treats muscle loss, osteoporosis, sexual issues.</p>Fórmula:C14H9F9N2OPureza:98%Cor e Forma:SolidPeso molecular:392.22S-40503
CAS:<p>S-40503 is an investigational selective androgen receptor modulator (SARM).</p>Fórmula:C15H23N3O3Cor e Forma:SolidPeso molecular:293.36Cyprodinil
CAS:<p>Cyprodinil is a fungicide blocking methionine synthesis in fungi and hinders B. cinerea, P. herpotrichoides, H. oryzae growth; it's also an AR agonist.</p>Fórmula:C14H15N3Cor e Forma:SolidPeso molecular:225.29BMS-641988
CAS:<p>BMS-641988 is a novel nonsteroidal androgen receptor antagonist for the treatment of prostate cancer.</p>Fórmula:C20H20F3N3O5SPureza:99.57% - 99.92%Cor e Forma:SoildPeso molecular:471.45GLPG0492
CAS:<p>GLPG0492 is a novel selective androgen receptor modulator.</p>Fórmula:C19H14F3N3O3Pureza:99.58%Cor e Forma:SolidPeso molecular:389.33ONC1-13B
CAS:<p>ONC1-13B, an androgen receptor antagonist, is used potentially for the treatment of prostate cancer.</p>Fórmula:C22H16F4N4O3SPureza:99.36% - 99.85%Cor e Forma:SolidPeso molecular:492.45Ralaniten triacetate
CAS:<p>Ralaniten triacetate (EPI-506) is a precursor of Ralaniten, an AR-NTD inhibitor, which can be used in the study of prostate and breast cancer.</p>Fórmula:C27H33ClO8Pureza:98.69%Cor e Forma:SolidPeso molecular:521.00Androgen receptor-IN-5
CAS:<p>Androgen receptor-IN-5 is a potent inhibitor of the androgen receptor with anticancer properties.</p>Fórmula:C22H10Cl2F4N4OSPureza:98%Cor e Forma:SolidPeso molecular:525.31(rel)-BMS-641988
CAS:<p>(rel)-BMS-641988, a relative configuration of the potent nonsteroidal androgen receptor antagonist BMS-641988, holds potential for prostate cancer research.</p>Fórmula:C20H20F3N3O5SPureza:98%Cor e Forma:SolidPeso molecular:471.45LGD-2941
CAS:<p>LGD-2941 is an androgen receptor modulator. LGD-2941 is used for the treatment of hypogonadism, female sexual dysfunction and menopausal syndrome.</p>Fórmula:C17H16F6N2O2Cor e Forma:SolidPeso molecular:394.31Androgen receptor degrader-1
CAS:<p>Androgen Receptor Degrader-1 (Compound 18) is a potent agent for androgen receptor degradation, applicable in cancer research [1].</p>Fórmula:C15H14ClN3O4Pureza:98%Cor e Forma:SolidPeso molecular:335.74Androgen receptor degrader-2
CAS:<p>Androgen Receptor Degrader-2 (Compound 9) is a potent degrader of androgen receptors, with potential application in cancer research [1].</p>Fórmula:C16H16ClN3O4Pureza:98%Cor e Forma:SolidPeso molecular:349.77N-Nitrosodicyclohexylamine
CAS:<p>N-Nitrosodicyclohexylamine (NDCHA), an N-nitrosocompound, exhibits anti-androgenic activity by competitively binding to the androgen receptor (AR) in opposition</p>Fórmula:C12H22N2OPureza:98%Cor e Forma:SolidPeso molecular:210.32Celiprolol hydrochloride
CAS:<p>Celiprolol hydrochloride (Selectrol) is a cardioselective beta-1 adrenergic antagonist that has intrinsic sympathomimetic activity.</p>Fórmula:C20H33N3O4·HClCor e Forma:White Crystalline SolidPeso molecular:415.96Androgen receptor antagonist 5
CAS:<p>AR antagonist 5 blocks AR (IC50: 6.17 μM), hinders LNCaP cell growth, and has anti-tumor effects in mouse models.</p>Fórmula:C21H15F4N5O3SCor e Forma:SolidPeso molecular:493.43Trimegestone
CAS:<p>Trimegestone, a highly effective oral progestogen, is used for endometrial protection, all doses inducing secretory endometrial transformation.</p>Fórmula:C22H30O3Pureza:98%Cor e Forma:SolidPeso molecular:342.47JJH260
CAS:<p>JJH260, a N-hydroxy hydantoin carbamate, inhibits AIG1 and ADTRP with IC50 values of 0.57 μM and 8.5 μM, respectively, and targets ABHD6, LYPLA1/2.</p>Fórmula:C29H34ClN5O5Cor e Forma:SolidPeso molecular:568.06JNJ-26146900
CAS:<p>JNJ-26146900 is a nonsteroidal androgen receptor (AR) ligand with tissue-selective activity in rats. JNJ-26146900 binds to the rat AR with a K(i) of 400nM.</p>Fórmula:C15H15F3N2O3SPureza:98%Cor e Forma:SolidPeso molecular:360.35VPC-14228
CAS:<p>VPC-14228 is a specific AR-DBD inhibitor that acts by inhibiting both Y594A and Q592A mutants.</p>Fórmula:C13H14N2OSPureza:99.96%Cor e Forma:SolidPeso molecular:246.33PLK1/BRD4-IN-1
CAS:<p>PLK1/BRD4-IN-1 (9b) is an orally active dual inhibitor of PLK1 (IC50: 22 nM) and BRD4 (IC50: 109 nM).</p>Fórmula:C31H43N9O2Cor e Forma:SolidPeso molecular:573.73
