NF-κB
O fator nuclear kappa-light-chain-enhancer de células B ativadas (NF-κB) é um fator de transcrição que regula a expressão de genes envolvidos em respostas imunes, inflamação, sobrevivência celular e proliferação. O NF-κB é ativado em resposta a vários estímulos, incluindo citocinas, patógenos e sinais de estresse. A desregulação da sinalização do NF-κB está associada a doenças inflamatórias crônicas, câncer e distúrbios autoimunes. Na CymitQuimica, oferecemos uma seleção abrangente de moduladores da via NF-κB para apoiar sua pesquisa em inflamação, oncologia e regulação imunológica.
Foram encontrados 390 produtos de "NF-κB"
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NF-κB-IN-11
CAS:NF-κB-IN-11 (Compound 3i) is an inhibitor of NF-κB, effectively blocking TNF-α-induced NF-κB pathway activation and the nuclear translocation of NF-κB.Fórmula:C19H18O5Pureza:98%Cor e Forma:SolidPeso molecular:326.34APC-0576
CAS:APC-0576, an (S,S)-isomer, blocks NF-kappaB gene activation and may reduce inflammation in human cells.Fórmula:C23H27N3O3Cor e Forma:SolidPeso molecular:393.481-Dehydro-[10]-gingerdione
CAS:1-Dehydro-[10]-gingerdione blocks IKKβ, curbs IκBα phosphorylation, halts NF-κB activity, and aids inflammation research.Fórmula:C21H30O4Cor e Forma:SolidPeso molecular:346.46IMD-biphenylB
CAS:IMD-biphenylB: Potent NF-κB inhibitor, curbs tumor growth with low inflammation and toxicity.Fórmula:C35H33N5O3Pureza:98%Cor e Forma:SolidPeso molecular:571.67Xanthine oxidase-IN-6
Xanthine oxidase-IN-6: potent oral mixed-type XOD inhibitor, IC50 1.37 µM, anti-hyperuricemia, renal protection.Fórmula:C29H34N2O15Cor e Forma:SolidPeso molecular:650.58Bay 65-1942 free base
CAS:Bay 65-1942 free base is an inhibitor of ATP-competitive and selective IKKβ.Fórmula:C22H25N3O4Pureza:98%Cor e Forma:SolidPeso molecular:395.45Avenanthramide-C methyl ester
CAS:Avenanthramide-C methyl ester blocks IKK/IκB phosphorylation, inhibits NF-κB, and reduces IL-6, IL-8, MCP-1 in endothelial cells (IC50 ~40 μM).Fórmula:C17H15NO6Cor e Forma:SolidPeso molecular:329.3GSK319347A
CAS:GSK319347A is a dual inhibitor of TBK1 and IKKε that inhibits IKK2 and can be used to study bladder and lung adenocarcinomas.Fórmula:C22H19N3O5S2Pureza:98.42%Cor e Forma:SolidPeso molecular:469.53IMD-ferulic
IMD-ferulic, a compound that forms covalent bonds, acts as an NF-κB modulator, enhancing the adjuvanticity of small molecule immune potentiators.Fórmula:C36H41N7O4Cor e Forma:SolidPeso molecular:635.76Ro 106-9920
CAS:Inhibitor of NF-κB activationFórmula:C10H7N5OSPureza:98%Cor e Forma:SolidPeso molecular:245.26NF-κB/PON1-IN-1
CAS:NF-κB/PON1-IN-1 (Compound 16) is an NF-κB/PON1 pathway inhibitor with antioxidant activity (IC50: 45.76 μM) and hepatoprotective activity.Fórmula:C20H16N6O4S2Cor e Forma:SolidPeso molecular:468.51TRAF-STOP inhibitor 6877002
CAS:TRAF-STOP 6877002 inhibits CD40-TRAF6, curbing leukocyte recruitment and macrophage activation/proliferation in plaques.Fórmula:C17H17NOPureza:99.76%Cor e Forma:SolidPeso molecular:251.32IMD-catechol
CAS:IMD-catechol: an imidazoquinolinone-based dimer with NF-κB activity; improves CT26 cancer treatment, low toxicity.Fórmula:C31H34N6O3Pureza:98%Cor e Forma:SolidPeso molecular:538.64PHA-408
CAS:PHA-408 is a novel potent, highly selective and ATP-competitive inhibitor of IKB kinase-2.Fórmula:C29H27ClFN7O2Pureza:98%Cor e Forma:SolidPeso molecular:560.02Anti-inflammatory agent 21
CAS:Compound 9o: orally active, low-toxicity anti-inflammatory; inhibits NO (IC50: 0.76 μM), blocks NF-κB/MAPK, reduces arthritis symptoms.Fórmula:C24H21FO6Cor e Forma:SolidPeso molecular:424.42HPN-01
CAS:HPN-01 (IKK inhibitor XII) is an IKK inhibitor that inhibits IKK-α and IKK-ε, prolongs the lifespan of mice, and can be used to study immune disorders.Fórmula:C19H16ClN3O3SPureza:98.07% - 98.17%Cor e Forma:SolidPeso molecular:401.87Ref: TM-T11573
2mg137,00€5mg222,00€10mg356,00€25mg708,00€50mg1.063,00€100mg1.603,00€200mg2.187,00€1mL*10mM (DMSO)245,00€TBK1/IKKε-IN-4
CAS:TBK1/IKKε-IN-4, a 6-aminopyrazolopyrimidine derivative, serves as a potent, selective inhibitor for TBK1 and IKKε, demonstrating IC50 values of 13 nM and 59 nMFórmula:C28H35N7O4Cor e Forma:SolidPeso molecular:533.62Edasalonexent
CAS:Edasalonexent (CAT-1004) is an orally available NF-κB inhibitor for the improvement of Duchenne muscular dystrophy.Fórmula:C31H42N2O3Pureza:99.13% - >99.99%Cor e Forma:SolidPeso molecular:490.68Ref: TM-T15198
1mg94,00€2mg137,00€5mg222,00€10mg356,00€25mg640,00€50mg1.009,00€1mL*10mM (DMSO)240,00€CID-2858522
CAS:CID-2858522 is an effective and specific antigen receptor-mediated NF-κB activation inhibitor (IC50: 70 nM).Fórmula:C28H39N3O3Pureza:96.12%Cor e Forma:SolidPeso molecular:465.63HE 3286
CAS:Triolex, an NF-kB inhibitor, is used potentially for the treatment of rheumatoid arthritis, ulcerative colitis.Fórmula:C21H30O3Cor e Forma:SolidPeso molecular:330.46ABD-350
CAS:ABD-350 is ligand-induced inhibitor of nuclear factor kappaB phosphorylation.Fórmula:C19H22F2O2Cor e Forma:SolidPeso molecular:320.37NF-κB-IN-3
CAS:NF-κB-IN-3 (Compound 2) is an NF-κB inhibitor (IC50: 0.70 μM) and can be used as an anti-tumour agent.Fórmula:C24H18ClF3N2O2Cor e Forma:SolidPeso molecular:458.86IT-901
CAS:IT-901: Oral NF-κB c-Rel inhibitor, IC50 0.1 µM. Blocks c-Rel/DNA binding, IC50 3 µM. Antitumor naphthalene derivative for lymphoma/myeloma therapy.Fórmula:C17H14N2O4SPureza:98.06%Cor e Forma:SolidPeso molecular:342.37BAY32-5915
CAS:BAY32-5915 is a selective inhibitor of IKKalpha.Fórmula:C10H7NO3Pureza:96.48% - 97%Cor e Forma:Yellow Crystalline PowderPeso molecular:189.17TNF-α-IN-18
CAS:TNF-α-IN-18 is a small molecule TNF-α inhibitor that blocks NF-κB translocation, alleviates sepsis in models, and protects against rheumatoid arthritis in mice.Fórmula:C16H7ClF2O4Pureza:99.77%Cor e Forma:SolidPeso molecular:336.67Sul-121 HCl
CAS:Sul-121 HCl combats COPD by reducing inflammation and AHR via oxidative stress inhibition.Fórmula:C18H27ClN2O3Pureza:98%Cor e Forma:SolidPeso molecular:354.87Bay 65-1942 hydrochloride
CAS:Bay 65-1942 hydrochloride is an inhibitor of ATP-competitive and selective IKKβ.Fórmula:C22H26ClN3O4Cor e Forma:SolidPeso molecular:431.91HSR1304
CAS:HSR1304 (5d) inhibits NFκB, key in diseases like cancer, offering research potential.Fórmula:C24H21ClN2O3Cor e Forma:SolidPeso molecular:420.89Asperbisabolane L
Asperbisabolane L, a sesquiterpenoid, combats inflammation by blocking NF-κB signaling and NO in BV-2 cells.Fórmula:C12H14O3Cor e Forma:SolidPeso molecular:206.24IMD-biphenylA
CAS:IMD-biphenylA, a novel imidazoquinolinone-based dimer, functions as an NF-κB immunomodulator and enhances the adjuvant properties of small molecule immuneFórmula:C35H33N5O2Pureza:98%Cor e Forma:SolidPeso molecular:555.67IKKβ-IN-1
CAS:IKKβ-IN-1 is a potent, orally active inhibitor of IkappaB (IKK-β) (IC50: 0.20 μM).Fórmula:C31H30N4O4SCor e Forma:SolidPeso molecular:554.66DHMEQ racemate
CAS:DHMEQ racemate is an NF-κB inhibitor. The activity of DHMEQ racemate is lower than (-)-DHMEQ.Fórmula:C13H11NO5Pureza:98%Cor e Forma:SolidPeso molecular:261.23NF-κB-IN-8
CAS:NF-κB-IN-8 is a competitive antagonist of LPS for MD-2 binding, and it impedes the expression of inflammatory factors by engaging MD-2.Fórmula:C24H21N3O3Pureza:98%Cor e Forma:SolidPeso molecular:399.44NF-κB-IN-2
CAS:NF-κB-IN-2 inhibits canonical NF-κB signaling induced by TNF-α in PC-3 cells.Fórmula:C15H18O3Cor e Forma:SolidPeso molecular:246.3XT2
CAS:XT2 is a potent, oral NF-κB-inducing kinase (NIK) inhibitor with an IC50 of 9.1 nM, reduces ALT levels, and curbs immune cell liver infiltration.Fórmula:C19H14FN5OSCor e Forma:SolidPeso molecular:379.41Gue1654
CAS:Gue1654 is an OXE-R inhibitor and cardiomyocyte apoptosis.Gue1654 can be used for the study of cardiovascular diseases.Fórmula:C23H17N3OS3Pureza:98.02% - 98.04%Cor e Forma:SolidPeso molecular:447.6DMX-129
CAS:DMX-129 is a chemical compound acting as an inhibitor for both ΙΚΚε and TBK-1, demonstrating efficacy with IC50 values of below 30 nM for each [1].Fórmula:C19H17FN8Cor e Forma:SolidPeso molecular:376.39CAY10575
CAS:CAY10575 (IKK2-IN-3) is a potent IKK2 inhibitor with potential anti-inflammatory activity for the study of inflammatory and endocrine diseases.Fórmula:C22H21N3O6S2Cor e Forma:SolidPeso molecular:487.55IRAK4-IN-20
CAS:IRAK4-IN-20 is a potent and orally active IRAK4 inhibitor (IC50:3.55 nM).Fórmula:C22H25F3N4O3Pureza:98.09%Cor e Forma:SolidPeso molecular:450.45Zharp2-1
CAS:Zharp2-1 is a RIPK2 inhibitor that alleviates MDP-induced peritonitis symptoms in mice and can be used to study inflammatory bowel disease (IBD).
Fórmula:C19H18N3O2PSPureza:99.41%Cor e Forma:SolidPeso molecular:383.4NFATc1-IN-1
CAS:NFATc1-IN-1 (A04) inhibits RANKL-induced osteoclast formation with 1.57 μM IC50, blocking NFATc1 translocation.Fórmula:C13H8F2INO2Pureza:99.98%Cor e Forma:SolidPeso molecular:375.11B022
CAS:B022 is an NF-κB-induced kinase (NIK) inhibitor that protects the liver from inflammation and injury caused by oxidative stress and toxins.Fórmula:C19H16ClN5OSPureza:99.74%Cor e Forma:SolidPeso molecular:397.88RIPK1-IN-9
CAS:RIPK1-IN-9, a potent dihydronaphthone, selectively inhibits RIPK1 with IC50 of 2 nM (U937) and 1.3 nM (L929).Fórmula:C26H25FN6O2Pureza:99.74%Cor e Forma:SolidPeso molecular:472.51Ref: TM-T63055
1mg148,00€5mg344,00€10mg474,00€25mg705,00€50mg944,00€100mg1.283,00€200mg1.710,00€1mL*10mM (DMSO)399,00€SP-100030
CAS:SP-100030: Strong NF-κB/AP-1 inhibitor, IC50=50 nM. Reduces IL-2, IL-8, TNF-alpha, and murine CIA.Fórmula:C14H5ClF9N3OPureza:99.79%Cor e Forma:SolidPeso molecular:437.65Ref: TM-T24816
1mg34,00€5mg70,00€10mg99,00€25mg230,00€50mg358,00€100mg513,00€500mgA consultar1mL*10mM (DMSO)78,00€Zabedosertib
CAS:Zabedosertib (BAY 1834845) is an inhibitor of IRAK4 with immunomodulatory potential.
Fórmula:C20H21F3N4O4SPureza:98.54%Cor e Forma:SolidPeso molecular:470.47TBK1-IN-1
CAS:TBK1-IN-1 is a TANK-binding kinase 1 inhibitor with anticancer activity.TBK1-IN-1 inhibits the expression of TBK1 downstream target genes, cxcl10 and ifnβ.Fórmula:C27H37N7O2Pureza:99.81% - >99.99%Cor e Forma:SolidPeso molecular:491.63Trovafloxacin mesylate
CAS:Trovafloxacin: broad-spectrum fluoroquinolone, blocks DNA gyrase/topoisomerase IV and PANX1 channel (IC50=4μM).Fórmula:C21H19F3N4O6SPureza:99.18%Cor e Forma:SolidPeso molecular:512.46IMD-vanillin
CAS:IMD-vanillin is a novel compound characterized as an imidazoquinolinone-derived dimer with NF-κB immunomodulatory properties.Fórmula:C37H45N7O4Pureza:98%Cor e Forma:SolidPeso molecular:651.8ACHP Hydrochloride
CAS:ACHP Hydrochloride (IKK-2 Inhibitor VIII) is a highly potent and selective IKK-β inhibitor with an IC50 of 8.5 nM.Fórmula:C21H25ClN4O2Pureza:99.83%Cor e Forma:SolidPeso molecular:400.9Ref: TM-T10237
1mg66,00€5mg144,00€10mg227,00€25mg375,00€50mg540,00€100mg777,00€500mg1.549,00€1mL*10mM (DMSO)159,00€Glabrescone C
CAS:Glabrescone C exhibits strong anti-inflammatory properties through direct binding to IKKα/β.
Fórmula:C19H22O7Cor e Forma:SolidPeso molecular:362.37Ginsenoside Rk1
CAS:Ginsenoside Rk1 is a component created by processing the ginseng plant at high temperatures.Fórmula:C42H70O12Pureza:98.46% - 99.13%Cor e Forma:SolidPeso molecular:767.00IMD-biphenylC
CAS:IMD-biphenylC: New, dual-action imidazoquinolinone dimer; inhibits tumor growth, low inflammation/toxicity.Fórmula:C35H33N5O3Pureza:98%Cor e Forma:SolidPeso molecular:571.67GGTI 2147
CAS:GGTI 2147 decreased Rac1 activity, down-regulated p65 expression, and ameliorated OGD/R-induced neuronal apoptosis.Fórmula:C28H30N4O3Pureza:98.24%Cor e Forma:SolidPeso molecular:470.56Dimethoxycurcumin
CAS:Dimethoxycurcumin is a stable curcumin analog causing epigenetic shifts in leukemia cells, affecting gene expression.Fórmula:C23H24O6Pureza:99.87%Cor e Forma:SolidPeso molecular:396.43Ref: TM-T19853
5mg52,00€10mg77,00€25mg133,00€50mg225,00€100mg330,00€200mg470,00€1mL*10mM (DMSO)52,00€(Rac)-BAY-985
CAS:(Rac)-BAY-985 is a potent, ATP-competitive and selective inhibitor of TBK1(IC50 of 1.5 nM),with antitumor efficacy.Fórmula:C27H30F3N9OPureza:98%Cor e Forma:SolidPeso molecular:553.58CGA-JK3
CAS:CGA-JK3 is an IkappaB kinase inhibitor in innate immune process.Fórmula:C15H19NO3Pureza:98%Cor e Forma:SolidPeso molecular:261.32PK68
CAS:PK68 selectively inhibits RIPK1 (IC50=90nM), potentially useful in inflammation and cancer metastasis studies.Fórmula:C22H24N4O3SPureza:98.09% - 99.64%Cor e Forma:SolidPeso molecular:424.52Ref: TM-T12493
1mg81,00€5mg170,00€10mg274,00€25mg518,00€50mg747,00€100mg938,00€1mL*10mM (DMSO)188,00€RIPK1-IN-16
CAS:RIPK1-IN-16 is an orally active, potent RIPK1 inhibitor that mitigates excessive inflammation via inhibition of RIPK1-mediated necroptosis in vivo.Fórmula:C20H19N5O2SPureza:98%Cor e Forma:SolidPeso molecular:393.46NF-κB-IN-13
CAS:NF-κB-IN-13 (compound 12) markedly suppresses LPS-induced NF-κB activation and NO synthesis in RAW264.7 macrophages, exhibiting anti-inflammatory properties [1Fórmula:C20H20O5Pureza:98%Cor e Forma:SolidPeso molecular:340.37IKK-IN-4
CAS:IKK-IN-4 is a potent and selective inhibitor of IkappaB kinase 2 with IC 50 values of 45 and 650 nM against IKKβ and IKKα, respectively [1].Fórmula:C18H19N5SCor e Forma:SolidPeso molecular:337.44Bay 65-1942 (R form)
CAS:Bay 65-1942 R form is the less active R-form of Bay 65-1942. Bay 65-1942 is a selective and ATP-competitive IKKβ inhibitor.Fórmula:C22H25N3O4Pureza:98%Cor e Forma:SolidPeso molecular:395.45PF-184
PF-184: potent IKK-2 inhibitor, selective over 30+ kinases; useful for asthma & COPD research. IC50: 37 nM.Fórmula:C32H32ClFN6O4Cor e Forma:SolidPeso molecular:619.09IKK-IN-1
CAS:IKK-IN-1 is an inhibitor of IKK.Fórmula:C22H26ClN3O4Pureza:98%Cor e Forma:SolidPeso molecular:431.91IR-Crizotinib
CAS:IR-Crizotinib is a conjugate of the near-infrared dye IR-786 and Crizotinib, an NF-κB-inducing kinase (NIK) inhibitor, with an IC50 of 3.381 μM for intracranialFórmula:C53H57Cl2FIN7OPureza:98%Cor e Forma:SolidPeso molecular:1024.88RIPK1-IN-4
CAS:RIPK1-IN-4 is a potent and selective type II kinase receptor interacting protein 1 (RIP1) kinase inhibitor and binds to a DLG-out inactive form of RIP1 (IC50s
Fórmula:C23H23N5O2Pureza:99.94%Cor e Forma:SolidPeso molecular:401.46GTCpFE
CAS:GTCpFE, a compound synthesized from Dimethyl fumarate (DMF) and Aspirin (ASA), inhibits IKKα/β in the NF-κB pathway, exhibiting anti-inflammatory activity by preventing p65 from entering the nucleus. It selectively inhibits cancer stem cell (CSC) activity by reducing the growth of mammospheres and the expression of the CD44+CD24- immune phenotype. Furthermore, GTCpFE targets breast cancer stem cells, crucial in aggressive cancer phenotypes that depend on NFκB and PGE2.Fórmula:C22H20O8Cor e Forma:SolidPeso molecular:412.39AS2690168 (free base)
CAS:AS2690168 freebase is an orally active inhibitor of RANKL signaling, capable of suppressing RANKL-induced osteoclastogenesis in RAW264 cells. AS2690168 is applicable in research related to pathological bone resorption.Fórmula:C17H13F3N4OCor e Forma:SolidPeso molecular:346.306NIK-IN-2
CAS:NIK-IN-2 (compound 1) is an effective inhibitor of NF-κB inducing kinase (NIK), exhibiting a pIC50 of 7.4. It plays a crucial role in cancer research.Fórmula:C20H22N4O3Cor e Forma:SolidPeso molecular:366.41RIPK2-IN-6
CAS:RIPK2-IN-6 (Compound 15a) is an inhibitor of RIPK that specifically targets the phosphorylation of RIPK2, thereby suppressing the NF-κB and MAPK signaling pathways. It has demonstrated anti-inflammatory and anti-fibrotic activities in a mouse model of colitis induced by Dextran sodium sulfate.Fórmula:C26H21NO3Cor e Forma:SolidPeso molecular:395.45AS2690168 hydrochloride
CAS:AS2690168 hydrochloride is an orally active inhibitor of RANKL signaling that can suppress RANKL-induced osteoclastogenesis in RAW264 cells. AS2690168 is applicable in research related to pathological bone resorption.Fórmula:C17H15Cl2F3N4OCor e Forma:SolidPeso molecular:419.228TBK1/IKKε-IN-1
CAS:TBK1/IKKε-IN-1 is a dual inhibitor of TBK1 and IKKε (IC50s of <100 nM).Fórmula:C28H26N4O5Pureza:98%Cor e Forma:SolidPeso molecular:498.53Anti-osteoporosis agent-11
CAS:Anti-osteoporosis agent-11 (compound 3k) is an anti-osteoporosis compound targeting osteoclasts. It exhibits its most prominent effect by inhibiting osteoclast differentiation, with an IC50 value of 0.36 μM. Additionally, Anti-osteoporosis agent-11 suppresses osteoclast formation, bone resorption, and the expression of osteoclast-specific genes by blocking the RANKL-induced mitogen-activated protein kinase (MAPK) and NF-κB signaling pathways.Fórmula:C23H17NO2Se2Cor e Forma:SolidPeso molecular:497.31MAY0132
CAS:MAY0132 is a potent and selective EPAC2 inhibitor with an IC50 of 0.4 μM. It significantly inhibits the replication of HMPV, AdV, and RSV, reduces cytokine/chemokine production induced by viral infections, and suppresses NF-κB activation. MAY0132 exhibits antiviral activity and can be used in respiratory virus infection research.Fórmula:C16H15ClF3NCor e Forma:SolidPeso molecular:313.745K-14585
CAS:K-14585 blocks PAR(2), reduces NFkappaB activity, and IL-8 response, but alone can boost IL-8.Fórmula:C51H56Cl2N8O4Cor e Forma:SolidPeso molecular:915.95NF-κB-IN-6
NF-κB-IN-6 (Compound 3d) is an anti-inflammatory agent that works by reducing the protein expression of iNOS and COX-2 by suppressing the NF-κB signalingFórmula:C14H20N2O3Cor e Forma:SolidPeso molecular:264.32DBMB
CAS:DBMB is a spleen tyrosine kinase (Syk) inhibitor that significantly suppresses Syk enzyme activity. It possesses anti-inflammatory properties by inhibiting NF-κB signaling, thereby reducing the production of inflammatory mediators such as nitric oxide (NO) and prostaglandin E2 (PGE2). DBMB can be utilized in research on inflammatory diseases.Fórmula:C24H22N4OCor e Forma:SolidPeso molecular:382.458TLR4/NF-κB/MAPK-IN-1
CAS:TLR4/NF-κB/MAPK-IN-1 is a novel antineuroinflammatory agent that functions by inhibiting the TLR4/NF-κB/MAPK pathways.Fórmula:C19H25BrO6Cor e Forma:SolidPeso molecular:429.3oxLig-1
CAS:OxLig-1 (7-Ketocholesteryl-9-carboxynonanoate) constitutes a lipid component of oxidized low-density lipoprotein (oxLDL) and serves as a critical ligand for β-glycoprotein I (β(2)-GPI). It induces nuclear translocation by activating the NF-κB pathway. Additionally, oxLig-1 is utilized in the study of atherosclerosis (AS).Fórmula:C36H58O5Cor e Forma:SolidPeso molecular:570.84NLRP3-IN-78
CAS:NLRP3-IN-78 (compound 21) is an NLRP3 inhibitor with a 46.72% inhibition rate of GSDMD-induced pyroptosis at 5 μM. It binds to the NLRP3 protein and prevents GSDMD-NT oligomerization. Additionally, NLRP3-IN-78 inhibits GSDMD cleavage and upstream NF-κB signaling, demonstrating anti-inflammatory activity.Fórmula:C12H5Cl2N3O4S2Cor e Forma:SolidPeso molecular:390.222Anti-inflammatory agent 6
Anti-inflammatory agent 6 blocks IKKα/β, IκBα, and NF-κB p65 phosphorylation, key to controlling inflammation.Fórmula:C22H20O12Cor e Forma:SolidPeso molecular:476.39TNFα activity modulator 3
CAS:TNFα Activity Modulator 3 (example 6) is a molecule that regulates TNF activity by inhibiting TNFα-induced NF-κB activation, making it applicable for related research.Fórmula:C27H24F2N6O2Cor e Forma:SolidPeso molecular:502.52HOIPIN-8 sodium
CAS:HOIPIN-8 sodium is a LUBAC inhibitor for the study of inflammatory and immune diseases.Fórmula:C23H15F2N4NaO3Pureza:97.34%Cor e Forma:SolidPeso molecular:456.38Ref: TM-T62826
1mg66,00€5mg145,00€10mg224,00€25mg358,00€50mg512,00€100mg707,00€200mg973,00€1mL*10mM (DMSO)146,00€UBS109
CAS:UBS109, a curcumin analog, is a DNA demethylating agent in pancreatic cancer that promotes osteoblast differentiation and mineralization.Fórmula:C18H17N3OPureza:99.48%Cor e Forma:SolidPeso molecular:291.35Ref: TM-T88314
2mg37,00€5mg54,00€10mg87,00€25mg157,00€50mg241,00€100mg369,00€200mg536,00€1mL*10mM (DMSO)59,00€Antiproliferative agent-22
CAS:Antiproliferative agent-22 is an anticancer compound that shows antiproliferative activity on MCF-7, MDA-MB-231 and MDA-MB-468 cells.Fórmula:C17H13N3O3Pureza:99.20% - 99.27%Cor e Forma:SolidPeso molecular:307.3Tripeptide-41
CAS:Tripeptide-41 (CG-Lipoxyn) is a bioactive peptide known for its ability to reduce fat accumulation.Fórmula:C29H30N4O5Pureza:98%Cor e Forma:SolidPeso molecular:514.572,3-Bis(3-indolylmethyl)indole
CAS:2,3-Bis(3-indolylmethyl)indole exhibits a concentration-dependent inhibition of RANKL-induced osteoclastogenesis, actin ring formation, and bone resorption.Fórmula:C26H21N3Cor e Forma:SolidPeso molecular:375.475ALPK1-IN-1
CAS:ALPK1-IN-1 (A001) strongly inhibits ALPK1, key for innate immunity & NF-κB signaling via TIFA/TRAF.
Fórmula:C25H32N6O2SCor e Forma:SolidPeso molecular:480.63ALPK1-IN-2
CAS:ALPK1-IN-2 is a potent inhibitor of ALPK1 (α-kinase 1) (IC50: 95 nM). ALPK1-IN-2 inhibits NF-κB (IC50: 1.31 μM).
Fórmula:C20H18F2N4O2SCor e Forma:SolidPeso molecular:416.44Ref: TM-T62162
Produto descontinuadoALPK1-IN-3
CAS:ALPK1-IN-3,serves as an ALPK1 inhibitor that dampens proinflammatory gene expression in the kidney and enhances survival in animal models of sepsis-induced
Fórmula:C20H16F2N4OSPureza:98%Cor e Forma:SolidPeso molecular:398.43
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