NF-κB
O fator nuclear kappa-light-chain-enhancer de células B ativadas (NF-κB) é um fator de transcrição que regula a expressão de genes envolvidos em respostas imunes, inflamação, sobrevivência celular e proliferação. O NF-κB é ativado em resposta a vários estímulos, incluindo citocinas, patógenos e sinais de estresse. A desregulação da sinalização do NF-κB está associada a doenças inflamatórias crônicas, câncer e distúrbios autoimunes. Na CymitQuimica, oferecemos uma seleção abrangente de moduladores da via NF-κB para apoiar sua pesquisa em inflamação, oncologia e regulação imunológica.
Foram encontrados 445 produtos de "NF-κB"
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Specnuezhenide
CAS:<p>Specnuezhenide (Nuezhenide) is isolated from the fruit of Ligustrum lucidum. It inhibits NF-κB and wnt/β-catenin signaling.Cost-effective and quality-assured.</p>Fórmula:C31H42O17Pureza:98% - 99.93%Cor e Forma:SolidPeso molecular:686.66γ-Tocotrienol
CAS:<p>γ-Tocotrienol (Plastochromanol) is one of the four types of tocotrienol, a type of vitamin E.</p>Fórmula:C28H42O2Pureza:97.27% - 98.13%Cor e Forma:SolidPeso molecular:410.63Ginsenoside Rk3
CAS:<p>Ginsenosides Rk3 & Rh4 may treat inflammation and ischemic heart disease.</p>Fórmula:C36H60O8Pureza:99.33% - 99.88%Cor e Forma:SolidPeso molecular:620.86MLN120B
CAS:<p>MLN120B is a selective and ATP competitive IKKβ inhibitor (IC50: 60 nM).</p>Fórmula:C19H15ClN4O2Pureza:98.92%Cor e Forma:SolidPeso molecular:366.8PTP1B-IN-1
CAS:<p>PTP1B-IN-1 (PTP1B inhibitor) is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B) (IC50 : 1.6 mM)</p>Fórmula:C8H8N2O3SPureza:99.27%Cor e Forma:SolidPeso molecular:212.23MD2-TLR4-IN-1
CAS:<p>MD2-TLR4-IN-1 is a myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex inhibitor.</p>Fórmula:C22H14Cl2N4OPureza:97.74%Cor e Forma:SolidPeso molecular:421.28Rubiadin-1-methyl ether
CAS:<p>Rubiadin-1-methyl ether: a natural inhibitor of bone resorption, blocking NF-κB p65 phosphorylation and IκBα degradation.</p>Fórmula:C16H12O4Pureza:98.32%Cor e Forma:SolidPeso molecular:268.26Rhynchophylline
CAS:<p>Rhynchophylline (Mitrinermine) is an alkaloid isolated from Crocus sativus and is widely used in anti-inflammatory and neuroprotective studies.</p>Fórmula:C22H28N2O4Pureza:99.44% - 99.98%Cor e Forma:Red Brown Or White Fine PowderPeso molecular:384.47ETHYL CAFFEATE
CAS:<p>Ethyl Caffeate (ETHYL 3,4-DIHYDROXYCINNAMATE) suppressed the differentiation of naive CD4+ T cells into Th1 in vitro.</p>Fórmula:C11H12O4Pureza:97.79%Cor e Forma:SolidPeso molecular:208.21GSK583
CAS:<p>GSK583 is a highly effective and specific RIP2 kinase inhibitor (IC50: 5 nM).</p>Fórmula:C20H19FN4O2SPureza:98.68% - 99.81%Cor e Forma:SolidPeso molecular:398.45Isovitexin
CAS:<p>1.</p>Fórmula:C21H20O10Pureza:99.79% - 99.97%Cor e Forma:SolidPeso molecular:432.38Denosumab
CAS:<p>Denosumab is a monoclonal antibody given subcutaneously that inhibits osteoclast activity by targeting the RANK ligand</p>Fórmula:C6404H9912N1724O2004S50Pureza:95.9% (SDS-PAGE); 98.4% (SEC-HPLC) - 99.90%Cor e Forma:LiquidPeso molecular:144.71 kDaJTP 0819958 - HOIPIN-1
<p>JTP-0819958: LUBAC inhibitor, IC50 2.8 μM; blocks NF-kB activation in vitro.</p>Fórmula:C17H13NaO4Pureza:99.95%Cor e Forma:SolidPeso molecular:304.27Diethylmaleate
CAS:<p>Diethylmaleate (Maleic acid, diethyl ester) is the diethyl ester of maleic acid and a glutathione-depleting compound that inhibits NF-kB.</p>Fórmula:C8H12O4Pureza:98%Cor e Forma:Colourless LiquidPeso molecular:172.18Chelidonic acid
CAS:<p>Chelidonic acid, in Chelidonium majus, acts as an analgesic, antimicrobial, CNS sedative, and has anti-inflammatory properties.</p>Fórmula:C7H4O6Pureza:99.03%Cor e Forma:SolidPeso molecular:184.1Ac2-26 acetate
<p>Ac2-26 acetate is an active N-terminal peptide of annexin A1(AnxA1).</p>Fórmula:C141H210N32O44SPureza:98%Cor e Forma:SolidPeso molecular:3089.43Sinomenine
CAS:<p>Sinomenine (Kukoline) is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the treatment of rheumatism and arthritis.</p>Fórmula:C19H23NO4Pureza:99.02% - 99.73%Cor e Forma:White PowderPeso molecular:329.39ISOGINKGETIN
CAS:<p>ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion.</p>Fórmula:C32H22O10Pureza:98% - 99.72%Cor e Forma:SolidPeso molecular:566.51AZD3264
CAS:<p>AZD3264 is a new type IKK2 inhibitor.</p>Fórmula:C21H23N5O4SPureza:98.98% - 99.17%Cor e Forma:SolidPeso molecular:441.5Astaxanthin
CAS:<p>Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.</p>Fórmula:C40H52O4Pureza:95.1% - 99.79%Cor e Forma:Needles From Acetone/Light Petroleum SolidPeso molecular:596.84
