NF-κB
O fator nuclear kappa-light-chain-enhancer de células B ativadas (NF-κB) é um fator de transcrição que regula a expressão de genes envolvidos em respostas imunes, inflamação, sobrevivência celular e proliferação. O NF-κB é ativado em resposta a vários estímulos, incluindo citocinas, patógenos e sinais de estresse. A desregulação da sinalização do NF-κB está associada a doenças inflamatórias crônicas, câncer e distúrbios autoimunes. Na CymitQuimica, oferecemos uma seleção abrangente de moduladores da via NF-κB para apoiar sua pesquisa em inflamação, oncologia e regulação imunológica.
Foram encontrados 444 produtos de "NF-κB"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
7-O-Methylaloeasinol
CAS:<p>7-O-Methylaloeasinol is a useful organic compound for research related to life sciences. The catalog number is T126468 and the CAS number is 105317-69-9.</p>Fórmula:C20H26O9Cor e Forma:SolidPeso molecular:410.419Nasunin
CAS:<p>Delphanin, also known as Nasunin, is an anthocyanin isolated as purple colored crystals from eggplant peels.</p>Fórmula:C42H47ClO23Cor e Forma:SolidPeso molecular:955.26Siegesbeckialide I
<p>Siegesbeckialide I effectively suppresses LPS-induced NO production in RAW264.7 murine macrophages by directly interacting with IKKα/β.</p>Fórmula:C20H28O6Cor e Forma:SolidPeso molecular:364.43NF-κB Signaling Compound Library
<p>A unique collection of xnum compounds targeting NF-κB signaling for high throughput screening and high content screening;</p>Cor e Forma:Odour SolidMesalamine impurity P
CAS:<p>Mesalamine impurity P, a 5-Aminosalicylic acid derivative, is a PPARγ agonist, inhibiting PAK1 and NF-κB.</p>Fórmula:C13H11NO6SCor e Forma:SolidPeso molecular:309.30NF-κΒ activator 1
CAS:<p>NF-κΒ activator 1 can activate the nf-kappa Β gene activator, EC50 of 0.9 microns.</p>Fórmula:C16H11FN2O2SPureza:99.58%Cor e Forma:SolidPeso molecular:314.33CAY10657
CAS:<p>CAY10657 has a wide range of applications in life science related research.</p>Fórmula:C17H20N4O3SCor e Forma:SolidPeso molecular:360.43PROTAC STING degrader-3
<p>PROTACSTING degrader-3 (Compound ST9) is a STINGPROTAC-type degrader with a DC50 of 0.62 μM. It induces STING degradation via the ubiquitin-proteasome pathway. This compound exerts anti-inflammatory effects by inhibiting the STING/TBK1/NF-κB signaling. Additionally, it offers renal protection and can be used in research on acute kidney injury.</p>Cor e Forma:Odour Solid3-(2-Hydroxyethyl) thio withaferin A
<p>3-(2-Hydroxyethyl) thio withaferin A, a steroidal lactone, blocks NF-kB, targets vimentin, and inhibits EPCR shedding.</p>Fórmula:C30H44O7SCor e Forma:SolidPeso molecular:548.73Licoagrochalcone C
CAS:<p>Licoagrochalcone C, a flavonoid, inhibits NF-κB and NO production effectively.</p>Fórmula:C21H22O5Cor e Forma:SolidPeso molecular:354.4TBK1/IKKε-IN-6
CAS:<p>TBK1/IKKε-IN-6 (example 110) is a potent inhibitor of TBK1 and IKKε, with IC50 values of less than 100 nM for both enzymes.</p>Fórmula:C31H36F2N8O4Cor e Forma:SolidPeso molecular:622.678Helenalin
CAS:<p>Helenalin: anti-inflammatory sesquiterpene, inhibits NF-κB by alkylating p65 cysteine groups, blocks DNA binding.</p>Fórmula:C15H18O4Pureza:98%Cor e Forma:SolidPeso molecular:262.3HS-243
CAS:<p>HS-243 is an inhibitor of IRAK-4 and IRAK-1 with IC50s of 20 and 24 nM. HS-243 shows anti-inflammatory and anticancer activity.</p>Fórmula:C17H16N4O3Pureza:98.62%Cor e Forma:SolidPeso molecular:324.33R-HP210
<p>R-HP210 blocks LPS-triggered IL-1β, IL-6, COX-2 gene transcription and has a 3.80 μM IC50 for NF-κB inhibition without activating GCs.</p>Fórmula:C22H19N3O2S2Cor e Forma:SolidPeso molecular:421.54Anti-osteoporosis agent-4
<p>Anti-osteoporosis agent-4 (Compound 11h) suppresses the differentiation of primary osteoclasts and attenuates RANKL-induced osteoclastogenesis.</p>Fórmula:C26H26ClN3O7SPureza:98%Cor e Forma:SolidPeso molecular:560.02Narlumosbart
CAS:<p>Narlumosbart (JMT103) is an IgG4κ monoclonal antibody that selectively binds to the receptor activator of nuclear factor-κB ligand (RANKL)[1].</p>Pureza:98%Cor e Forma:Liquid12-Oxo phytodienoic acid
CAS:<p>12-oxo PDA boosts alkaloid production in E. californica, enhances B. dioica tendril curls, and blocks JA-induced cell death in A. fru mutants.</p>Fórmula:C18H28O3Pureza:98%Cor e Forma:SolidPeso molecular:292.41OT-551 HCl
CAS:<p>OT-551 HCl is an NF-Κb inhibitor, a disubstituted hydroxylamine with antioxidant properties can be used for the treatment of cataracts and age-related macular</p>Fórmula:C13H24ClNO3Pureza:99.71%Cor e Forma:SolidPeso molecular:277.79Murrayafoline A
CAS:<p>Murrayafoline A is a useful organic compound for research related to life sciences. The catalog number is T124835 and the CAS number is 4532-33-6.</p>Fórmula:C14H13NOCor e Forma:SolidPeso molecular:211.264DTP3
CAS:<p>DTP3 is a selective MKK7/GADD45β inhibitor, which inhibits cancer-selective NF-κB survival pathway.</p>Fórmula:C26H35N7O5Cor e Forma:SolidPeso molecular:525.6
