CCR
Os receptores de quimiocinas C-C (CCRs) são um grupo de GPCRs que respondem às quimiocinas, moléculas de sinalização que orientam a migração de células imunológicas para locais de inflamação ou infecção. Os CCRs desempenham papéis cruciais nas respostas imunológicas, inflamação e no desenvolvimento de várias doenças, incluindo distúrbios autoimunes e câncer. A modulação da atividade dos CCRs está sendo explorada como uma estratégia terapêutica para condições como artrite reumatoide, esclerose múltipla e infecção pelo HIV. Na CymitQuimica, oferecemos uma gama de moduladores de CCR de alta qualidade para apoiar sua pesquisa em imunologia, inflamação e desenvolvimento terapêutico.
Foram encontrados 140 produtos de "CCR"
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ML604086
CAS:ML604086 suppresses CCL1 mediated chemotaxis and enhances intracellular Ca2 concentrations.Fórmula:C27H32N4O4SPureza:99.91%Cor e Forma:SolidPeso molecular:508.63CCR2-RA-[R]
CAS:CCR2-RA-[R] is a C-C chemokine receptor type 2 (CCR2) allosteric antagonist (IC50: 103 nM).Fórmula:C18H19ClFNO3Pureza:99.7%Cor e Forma:SolidPeso molecular:351.8CCX140
CAS:CCX140 (CCX140-B) (CCX140-B) is an antagonist of CCR2.Fórmula:C20H13ClF3N5O3SPureza:99.66% - 99.95%Cor e Forma:SolidPeso molecular:495.86AZ084
CAS:AZ084 is a potent, selective, allosteric, and oral active CCR8 antagonist (Ki: 0.9 nM). It has the potential to treat asthma.Fórmula:C26H34N4O2Pureza:97.12%Cor e Forma:SolidPeso molecular:434.57Ref: TM-T10425
1mg84,00€5mg161,00€10mg245,00€25mg406,00€50mg572,00€100mg772,00€200mg1.035,00€1mL*10mM (DMSO)172,00€INCB-9471
CAS:INCB-9471 is a CCR5 antagonist with anti-HIV activity and inhibits the interaction between HIV-1 gp120.Fórmula:C30H40F3N5O2Pureza:98.80%Cor e Forma:SolidPeso molecular:559.666Mogamulizumab
CAS:Mogamulizumab is a monoclonal antibody targeting CC chemokine receptor 4 with anticancer effects, used in ATLL and CTCL studies.Pureza:SDS-PAGE:97.3%;SEC-HPLC:99.4%Cor e Forma:LiquidPeso molecular:146.43 kDaLeronlimab
CAS:Leronlimab (PRO 140), a humanized IgG4 monoclonal antibody, targets CCR5 to combat HIV and cancer.Pureza:SDS-PAGE:95.0%;SEC-HPLC:99.6%Cor e Forma:LiquidPeso molecular:146.66 kDaRS102895 hydrochloride
CAS:RS102895 hydrochloride is a potent antagonist of CCR2(IC50 of 360 nM).Fórmula:C21H22ClF3N2O2Pureza:98.95%Cor e Forma:SolidPeso molecular:426.86J-113863
CAS:J-113863 is also a potent antagonist of the human CCR3 (IC50 of 0.58 nM) , but a weak antagonist of the mouse CCR3 (IC50 of 460 nM).Fórmula:C30H37Cl2IN2O2Pureza:95.11%Cor e Forma:SolidPeso molecular:655.44Ref: TM-T11699
1mg56,00€2mg82,00€5mg119,00€10mg160,00€25mg288,00€50mg500,00€100mg718,00€1mL*10mM (DMSO)170,00€MK-0812 Succinate
CAS:MK-0812 Succinate is an effective and selective CCR2 antagonist.Fórmula:C28H40F3N3O7Pureza:98.62% - 99.93%Cor e Forma:SolidPeso molecular:587.63Met-RANTES,human,acetate
Met-RANTES (human) acetate is the acetate salt form of Met-RANTES (human). It acts as an antagonist for CCR1 and CCR5 receptors. This compound inhibits the human chemokines MIP-1α and MIP-1β, with respective IC50 values of 5 and 2 nM. Additionally, Met-RANTES (human) acetate reduces bone destruction and alleviates adjuvant-induced arthritis (AIA) in rats.Cor e Forma:Odour SolidMLN-3897 TFA
MLN-3897 TFA is a potent CCR1 antagonist that inhibits the binding of 125I-MIP-1α to THP-1 cell membranes.Fórmula:C32H32ClF3N2O6Pureza:98.62%Cor e Forma:SolidPeso molecular:633.05Ref: TM-T28072L
1mg115,00€5mg245,00€10mg363,00€25mg562,00€50mg775,00€100mg1.035,00€200mg1.406,00€1mL*10mM (DMSO)A consultarINCB 3284 dimesylate
CAS:INCB 3284 dimesylate: oral CCR2 antagonist, blocks MCP-1/hCCR2 binding (IC50: 3.7 nM), potential in acute liver failure research.Fórmula:C28H39F3N4O10S2Pureza:98%Cor e Forma:SolidPeso molecular:712.76BMS-753426
CAS:BMS-753426 is a potent and orally bioavailable antagonist of CCR2 .
Fórmula:C25H33F3N6O2Cor e Forma:SolidPeso molecular:506.574INCB3344 R-isomer
INCB3344 is a potent CCR2 antagonist. INCB3344 R-isomer is the R-isomer of INCB3344.Fórmula:C29H34F3N3O6Pureza:98%Cor e Forma:SolidPeso molecular:577.59Bertilimumab
CAS:Bertilimumab (CAT 213; iCo-008), a human monoclonal antibody that targets eotaxin-1 (CCL11), shows promise in the research of allergic disorders [1].
Cor e Forma:LiquidCCR4 antagonist 3
CAS:Orally active CCR4 antagonist with piperidinyl-azetidine; IC50: 22 nM (calcium flux), 50 nM (CTX); antitumor effects.Fórmula:C24H27Cl2N7OCor e Forma:SolidPeso molecular:500.43CCR4 antagonist 3 hydrochloride
CAS:Orally active CCR4 antagonist 3 hydrochloride with potent selectivity, IC50s: 22/50 nM; has antitumor properties.Fórmula:C24H27Cl2N7O·xHClCor e Forma:SolidZn-DPA-maytansinoid conjugate 1
Zn-DPA-maytansinoid 1 targets checkpoints, shrinks tumors, and heats TME.Fórmula:C115H145ClN18O31S2Zn2Cor e Forma:SolidPeso molecular:2505.83Maceneolignan H
CAS:Maceneolignan H, a neolignane from Myristica fragrans, selectively blocks CCR3 (EC50=1.4μM) with allergy research potential.Fórmula:C24H30O7Cor e Forma:SolidPeso molecular:430.49PF-232798
CAS:PF-232798 is a second generation oral CCR5 antagonist with potent broad-spectrum anti-HIV-1 activity.Fórmula:C29H40FN5O2Cor e Forma:SolidPeso molecular:509.66CKLF1-C27 TFA
CKLF1-C27 peptide activates ERK1/2 via CCR4, competes with CKLF1, promotes HUVEC growth, and has psoriasis research potential.Fórmula:C153H244F3N39O39Cor e Forma:SolidPeso molecular:3310.8SQA1
CAS:SQA1 is a derivative of a phthalamide (SQA) and acts as a CCR6 antagonist with a Kd of 250 nM, as well as a CXCR2 inhibitor. It occupies an intracellular pocket that overlaps with the G protein binding site, stabilizing the pocket's closed conformation.Fórmula:C22H26N4O5Cor e Forma:SolidPeso molecular:426.47CCR8 antagonist 1
CAS:CCR8 antagonist 1 is an antagonist of C-C Motif Chemokine Receptor 8 (CCR8) with a Ki value of 1.6 nM.Fórmula:C26H29N3O5SPureza:99.51%Cor e Forma:SolidPeso molecular:495.59Plozalizumab
CAS:Plozalizumab (MLN-1202) is a humanized selective and potent anti-CCR2 antibody.Plozalizumab has antitumor activity.Plozalizumab is used in the study of
Pureza:96.4%Cor e Forma:LiquidPeso molecular:146.02 kDaCH-0076989
CAS:CH-0076989 is a chemokine receptor CCR3 agonist.Fórmula:C24H22Br2N2O2Cor e Forma:SolidPeso molecular:530.25CCR6 antagonist 2
CCR6 antagonist2 (Compound 20c) acts as a CCR6 antagonist with a Ki of 1.1 nM. It inhibits CCL20-induced calcium influx with an IC50 of 4.9 nM and suppresses the chemotactic migration of CCR6+ T cells with an IC50 of 190 nM.Fórmula:C19H24N4O4Cor e Forma:SolidPeso molecular:372.42CMKLR1 antagonist 1
CMKLR1 antagonist 1 (compound S-26d) is a potent, orally active antagonist of the chemokine-like receptor 1 (CMKLR1), exhibiting a pIC50 of 7.44 in hCMKLR1-Cor e Forma:Odour SolidHGS101
HGS101 is a fully humanized CCR5 monoclonal antibody that exhibits high affinity for CCR5. It binds to the second extracellular loop (ECL-2) and functions as a signaling antagonist. HGS101 restores the inhibitory effect of Maraviroc in Maraviroc-resistant HIV-1 infected PBMCs. In an uninfected simian immunodeficiency virus model of rhesus monkeys, HGS101 shows anti-HIV activity by inhibiting CCR5 signaling.Cor e Forma:Odour LiquidCCR6 antagonist 1
CAS:CCR6 antagonist 1 blocks CCL20/CCR6, aiding autoimmune and IBD research.
Fórmula:C17H12F3NO2Pureza:99.83%Cor e Forma:SoildPeso molecular:319.28CHS-114
CHS-114 (SRF-114) is a fully human IgG1 antibody targeting the (CCR8) receptor. It shows potential for research in head and neck squamous cell carcinoma (HNSCC). The isotype control for CHS-114 can be referred to as HumanIgG1kappa, Isotype Control.Cor e Forma:Odour LiquidTagmokitug
CAS:Tagmokitug is a humanized IgG1κ monoclonal antibody inhibitor targeting CCR8. It exhibits anti-tumor activity and is applicable in cancer immunotherapy research, including studies on breast cancer, colon cancer, and lung cancer.Lanerkitug
Lanerkitug is a humanized IgG1λ2 antibody that targets CCR8, with HumanIgG1lambda2, Isotype Control serving as its corresponding isotype control.Cor e Forma:Odour LiquidCafelkibart
Cafelkibart is a chimeric IgG1κ monoclonal antibody targeting CCR8, with HumanIgG1kappa, Isotype Control serving as its corresponding isotype control.Cor e Forma:Odour LiquidWAY-639418
CAS:WAY-639418 has potential anti-inflammatory and anti-HIV activity and can be used to study CCR5-mediated inflammatory and immunomodulatory diseases.Fórmula:C17H16ClN5Pureza:99.89%Cor e Forma:SolidPeso molecular:325.8Chemokine Inhibitor Library
A unique collection of xnum chemokines or chemokine receptors targeted compounds for high throughput and high content screening;
Cor e Forma:Odour Solid2-Methoxyhydroquinone
CAS:2-Methoxyhydroquinone inhibits MAO-A and MAO-B and reduces TNF-α-induced CCL2 production, a precursor for synthesising the Hsp90 inhibitor Geldanamycin.Fórmula:C7H8O3Pureza:98.25%Cor e Forma:SolidPeso molecular:140.14CCR6 inhibitor 1
CAS:CCR6 inhibitor 1 selectively blocks CCR6 (0.45 nM in monkeys, 6 nM in humans), aiding in vitro/vivo disease studies.
Fórmula:C24H23F3N4O3SPureza:99.89%Cor e Forma:SolidPeso molecular:504.52Nebokitug
Nebokitug is a humanized IgG1κ antibody targeting CCL24, with HumanIgG1kappa, Isotype Control serving as its corresponding isotype control.Cor e Forma:Odour LiquidDenikitug
Denikitug is a chimeric antibody of the IgG1κ type that targets CCR8, with its corresponding isotype control being HumanIgG1kappa, Isotype Control.Cor e Forma:Odour LiquidCCR2 antagonist 1
CAS:CCR2 antagonist 1 is a high-affinity and long-residence-time antagonist of CCR2 (Ki: 2.4 nM).Fórmula:C28H32BrF3N2OCor e Forma:SolidPeso molecular:549.47NI-0701
NI-0701 is a humanized antibody targeting CCL5/RANTES.Pureza:95.4% (SDS-PAGE); 99.4% (SEC-HPLC) - 95.4% (SDS-PAGE); 99.4% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:144.83 kDaCCR8 agonist 1
CCR8 agonist1 (Compound 2) is an activator of CCR8 and is applicable in studies related to autoimmune diseases.Fórmula:C22H29NO3Cor e Forma:SolidPeso molecular:355.47ZK 756326
CAS:ZK 756326: Selective CCR8 agonist, IC50 1.8 μM (human), 2.6 μM (mouse), no CCR4/5, CXCR3/4 action, 28-fold selectivity vs 26 GPCRs, anti-HIV fusion.Fórmula:C21H28N2O3Pureza:99.43%Cor e Forma:SolidPeso molecular:356.46Cenicriviroc
CAS:Cenicriviroc (TAK-652), oral CCR2/CCR5 blocker, inhibits HIV-1/HIV-2, with strong anti-infective/anti-inflammatory effects.Fórmula:C41H52N4O4SPureza:97.87%Cor e Forma:SolidPeso molecular:696.94Ref: TM-TQ0297
1mg63,00€2mg90,00€5mg133,00€10mg212,00€25mg423,00€50mg550,00€100mg715,00€200mg964,00€1mL*10mM (DMSO)200,00€AZD2098
CAS:AZD2098 is a potent CC-chemokine receptor 4 (CCR4) inhibitor used for asthma research.Fórmula:C11H9Cl2N3O3SPureza:99.80% - >99.99%Cor e Forma:SolidPeso molecular:334.18Ref: TM-T4300
1mg34,00€5mg66,00€10mg105,00€25mg217,00€50mg334,00€100mg502,00€500mg1.063,00€1mL*10mM (DMSO)73,00€R243
CAS:R243 is CCR8 signaling and chemotaxis inhibitor.Fórmula:C21H27NO4Pureza:99.03%Cor e Forma:SolidPeso molecular:357.44Ref: TM-T24700
1mg40,00€2mg52,00€5mg80,00€10mg117,00€25mg207,00€50mg333,00€100mg495,00€1mL*10mM (DMSO)90,00€Vicriviroc maleate
CAS:Vicriviroc maleate (SCH-417690 (maleate))(Sch-417690) is a piperazine-based CCR5 receptor antagonist with activity against human immunodeficiency virus.
Fórmula:C32H42F3N5O6Pureza:98.16% - 98.37%Cor e Forma:SolidPeso molecular:649.7Bindarit
CAS:Bindarit is a selective inhibitor of monocyte chemoattractant proteins MCP-1/CCL2, MCP-3/CCL7 and MCP-2/CCL8.Cost-effective and quality-assured.Fórmula:C19H20N2O3Pureza:98.35% - 98.55%Cor e Forma:SolidPeso molecular:324.37Ref: TM-T6413
1mg35,00€2mg50,00€5mg75,00€10mg110,00€25mg178,00€50mg314,00€100mg492,00€200mg710,00€1mL*10mM (DMSO)84,00€BX471
CAS:BX471 (BX 471) is a potent, selective non-peptide CCR1 antagonist.Fórmula:C21H24ClFN4O3Pureza:98% - 99.98%Cor e Forma:SolidPeso molecular:434.89Ref: TM-T2375
1mg35,00€5mg86,00€10mg117,00€25mg200,00€50mg313,00€100mg489,00€200mg740,00€1mL*10mM (DMSO)95,00€SB297006
CAS:SB297006 is an antagonist of C-C chemokine receptor 3, which normally is activated by eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1δ.Fórmula:C18H18N2O5Pureza:99.59%Cor e Forma:SolidPeso molecular:342.35Vicriviroc
CAS:Vicriviroc, also known as MK4176 is a CCR5 antagonist.Fórmula:C28H38F3N5O2Cor e Forma:SolidPeso molecular:533.63CCR2 antagonist 4 hydrochloride
CAS:CCR2 antagonist 4 hydrochloride is a specific CCR2 antagonist (IC50s: 180 nM for CCR2b). It potently inhibits MCP-1-induced chemotaxis (IC50: 24 nM).Fórmula:C21H22Cl2F3N3O2Cor e Forma:SolidPeso molecular:476.32RS 504393
CAS:RS 504393 is a highly selective CCR2 chemokine receptor antagonist (IC50s: 89 nM and > 100 μM for human recombinant CCR2 and CCR1).Fórmula:C25H27N3O3Pureza:98.64% - 99.62%Cor e Forma:SolidPeso molecular:417.5Vercirnon sodium
CAS:Vercirnon (GSK1605786A) sodium: oral CCR9 antagonist, inhibits Ca2+ mobilization/chemotaxis, IC50 = 2.6-5.4 nM, selective for CCR9 vs. CCR1-12/CX3CR1-7.Fórmula:C22H21ClN2NaO4SCor e Forma:SolidPeso molecular:467.92RE-640
CAS:NSC-5844 (RE-640) (RE640) is a bisquinoline compound with C-C chemokine receptor type 1 (CCR1)-agonistic activities.Fórmula:C20H16Cl2N4Pureza:99.60% - 99.87%Cor e Forma:SolidPeso molecular:383.27BMS-813160
CAS:BMS-813160 is the first dual CCR2/CCR5 antagonist to enter Clinical development for cardiovascular.Fórmula:C25H40N8O2Pureza:99.66% - 99.79%Cor e Forma:SolidPeso molecular:484.64Ref: TM-T4584
1mg63,00€5mg137,00€10mg187,00€25mg341,00€50mg567,00€100mg810,00€500mg1.644,00€1mL*10mM (DMSO)145,00€DAPTA
CAS:DAPTA (Adaptavir) is an inhibitor of CCR5, shows potent anti-HIV activities.Fórmula:C35H56N10O15Pureza:>99.99%Cor e Forma:SolidPeso molecular:856.887,4'-Dihydroxyflavone
CAS:7,4'-Dihydroxyflavone (4',7-Dihydroxyflavone) can induce transcription of nodulation (nod) genes in Rhizobium meliloti.Fórmula:C15H10O4Pureza:99.39% - 99.6%Cor e Forma:SolidPeso molecular:254.24PF-4136309
CAS:PF-4136309 (INCB8761) is a specific, effective, and orally bioavailable CCR2 antagonist.Fórmula:C29H31F3N6O3Pureza:98.85% - 99.47%Cor e Forma:SolidPeso molecular:568.59C-021
CAS:C 021 dihydrochloride is a potent CCR4 antagonist.Fórmula:C27H41N5O2Pureza:99.74% - 99.90%Cor e Forma:SolidPeso molecular:467.65Ref: TM-T21870
1mg49,00€2mg67,00€5mg90,00€10mg144,00€25mg286,00€50mg444,00€100mg622,00€1mL*10mM (DMSO)90,00€Maraviroc
CAS:Maraviroc: a CCR5 antagonist blocking HIV-1 entry; IC50s—MIP-1α: 3.3nM, MIP-1β: 7.2nM, RANTES: 5.2nM.Fórmula:C29H41F2N5OPureza:97.13% - 99.59%Cor e Forma:Brown SolidPeso molecular:513.67Ref: TM-T6016
5mg49,00€10mg90,00€25mg152,00€50mg259,00€100mg465,00€200mg600,00€500mg945,00€1mL*10mM (DMSO)56,00€Vercirnon
CAS:Vercirnon (Traficet-EN) is a selective and potent antagonist of CCR9 (IC50: 10 nM). It is also used in the research of inflammatory bowel diseases.Fórmula:C22H21ClN2O4SPureza:99.23%Cor e Forma:SolidPeso molecular:444.93Ref: TM-T17225
1mg105,00€5mg259,00€10mg406,00€25mg680,00€50mg938,00€100mg1.301,00€500mg2.593,00€1mL*10mM (DMSO)363,00€AZD-4818
CAS:AZD-4818 (CCR1 antagonist) is a chemokine CCR1 antagonist for the treatment of chronic obstructive pulmonary disease.Fórmula:C27H32Cl2N2O7Pureza:99.01%Cor e Forma:SolidPeso molecular:567.46RS102895
CAS:RS102895 is a potent CCR2 antagonist (IC50: 360 nM) and shows no effect on CCR1.Fórmula:C21H21F3N2O2Pureza:97.64% - 99.80%Cor e Forma:SolidPeso molecular:390.4TAK-779
CAS:TAK-779 (Takeda 779) is an antagonist of chemokine receptor 5 (CCR5), CCR2b, and CXC chemokine receptor 3 (CXCR3).Fórmula:C33H39ClN2O2Pureza:99.21%Cor e Forma:SolidPeso molecular:531.13INCB 3284
CAS:INCB 3284, a potent human CCR2 antagonist with an IC50 of 3.7 nM, is researchable for acute liver failure and inhibits MCP-1/hCCR2 binding.Fórmula:C26H31F3N4O4Pureza:97.81% - 99.42%Cor e Forma:SolidPeso molecular:520.54Tivumecirnon
CAS:Tivumecirnon (FLX475) is a selective and oral CCR4 antagonist inhibits the infiltration and migration of Treg into the tumour microenvironment, antitumourFórmula:C24H27Cl2F3N6OPureza:99.88%Cor e Forma:SolidPeso molecular:543.41Ref: TM-T69834
1mg171,00€5mg418,00€10mg666,00€25mg1.334,00€50mg2.071,00€100mg2.879,00€1mL*10mM (DMSO)500,00€CCR1 antagonist 7
CAS:CCR1 antagonist 7 (compound 16r) is an antagonist of chemokine receptor 1 (CCR1) with an IC 50 of 4 nM [1].Fórmula:C21H24ClN5O3SPureza:98%Cor e Forma:SolidPeso molecular:461.96YM022
CAS:YM022 is a highly effective and selective gastrin/cholecystokinin (CCK)-B receptor antagonist.Fórmula:C32H28N4O3Pureza:98%Cor e Forma:SolidPeso molecular:516.59TAK-220
CAS:TAK-220: Oral CCR5 antagonist. IC50: 3.5 nM (RANTES), 1.4 nM (MIP-1α).Fórmula:C31H41ClN4O3Pureza:98%Cor e Forma:SolidPeso molecular:553.14MLN3126
CAS:MLN3126: Oral CCR9 blocker, hinders CCL25-triggered chemotaxis/thymocyte calcium influx, IC50 of 6.3 nM.Fórmula:C21H19ClN2O5SCor e Forma:SolidPeso molecular:446.9AZD-1678
CAS:AZD-1678 is a potent CCR4 receptor antagonist.Fórmula:C11H8Cl2FN3O3SCor e Forma:SolidPeso molecular:352.17CCR1 antagonist 9
CAS:CCR1 antagonist 9 (compound 19e) is a selective CCR1 antagonist based on aziridine. CCR1 inhibition in calcium flux assays.Fórmula:C20H16FN5O3SPureza:99.13%Cor e Forma:SolidPeso molecular:425.44Ref: TM-T10710
1mg101,00€5mg241,00€10mg402,00€25mg727,00€50mg1.046,00€100mg1.525,00€1mL*10mM (DMSO)265,00€ALK4290
CAS:ALK4290 (AKST4290), a potent oral CCR3 inhibitor with a Ki of 3.2 nM, may treat macular degeneration and Parkinsonism.Fórmula:C27H34ClN5O3Cor e Forma:SolidPeso molecular:512.04RPT193
CAS:RPT193 is an oral CCR4 inhibitor reducing Th2 cell migration in atopic dermatitis, asthma, and allergies.Fórmula:C27H34Cl3N5O2Cor e Forma:SolidPeso molecular:566.95CCR8 antagonist 2
CAS:CCR8 antagonist 2 blocks CCR8 activity, mainly on Treg and Th2 cells, for treating related diseases. See WO2022000443A1, compound 220.Fórmula:C23H30ClN3O3SCor e Forma:SolidPeso molecular:464.02BI-6901
CAS:BI-6901 is a CCR10 antagonist. In a mouse model of DNFB exposure hypersensitivity, BI 6901 displays its anti-inflammatory response in a dose-dependent manner.Fórmula:C23H27N5O3SPureza:99.83% - 99.94%Cor e Forma:SolidPeso molecular:453.56CCR2 antagonist 3
CAS:CCR2 antagonist 3 (AZD-2927) is an antagonist of CCR2.Fórmula:C17H25FN2O2Pureza:99.87%Cor e Forma:SolidPeso molecular:308.39Ref: TM-T10712
1mg66,00€5mg147,00€10mg225,00€25mg398,00€50mg532,00€100mg745,00€200mg982,00€1mL*10mM (DMSO)161,00€CCR4 antagonist 3-1
CAS:CCR4 antagonist 3-1 is a weak inhibitor of [125I]TARC binding and CEM cell migration, with IC50 values of 1.7 μM and 6.4 μM, respectively.
Fórmula:C14H12N2SPureza:99.53%Cor e Forma:SolidPeso molecular:240.32PNU-177864 hydrochloride
CAS:PNU-177864 hydrochloride is a potent, selective and orally active antagonist of dopamine D3 receptor.
Fórmula:C18H22ClF3N2O3SPureza:99.95%Cor e Forma:SolidPeso molecular:438.89PNU-177864
CAS:PNU-177864 is a selective dopamine D3 receptor antagonist.Fórmula:C18H21F3N2O3SPureza:99.92%Cor e Forma:SolidPeso molecular:402.43C-021 dihydrochloride
CAS:C-021 dihydrochloride is a potent CCR4 antagonist. It potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM.Fórmula:C27H43Cl2N5O2Pureza:98.67%Cor e Forma:SolidPeso molecular:540.57CCX354
CAS:CCX354 (CCR1 antagonist 1) is a potent small molecule CCR1 antagonist with anti-inflammatory activity for the treatment of rheumatoid arthritis.Fórmula:C22H22ClN7O2Pureza:99.43% - 99.44%Cor e Forma:SolidPeso molecular:451.91APC-3316 tosylate
CAS:APC-3316 tosylate is a vinyl sulfone cysteine protease inhibitor and selective CCR4 antagonist.Fórmula:C39H46N4O7S2Cor e Forma:SolidPeso molecular:746.94GW 766994
CAS:GW 766994 is a specific and oral chemokine receptor-3 (CCR3) antagonist. It has the potential for asthma and eosinophilic bronchitis treatment.Fórmula:C21H24Cl2N4O3Pureza:98.77%Cor e Forma:SolidPeso molecular:451.35AF-399/42018025
CAS:AF-399/42018025 is a small-molecule CCR4 antagonist applied to investigate chemokine-mediated immune cell trafficking and inflammatory disease mechanisms.Fórmula:C26H16ClN3O4S3Pureza:99.96%Cor e Forma:SolidPeso molecular:566.07BMS-457
CAS:BMS-457 is a potent, CCR1-selective antagonist.Fórmula:C24H35ClN2O4Pureza:98%Cor e Forma:SolidPeso molecular:451JNJ-27141491
CAS:JNJ-27141491 is a potent, noncompetitive antagonist of human CCR2.Fórmula:C17H15F2N3O3SPureza:98%Cor e Forma:SolidPeso molecular:379.38Cosalane
CAS:Cosalane (NSC 658586) is an HIV replication inhibitor and an inhibitor of chemokine receptor 7 (CCR7) signalling in humans and mice.Fórmula:C45H60Cl2O6Pureza:99.53% - 99.78%Cor e Forma:SolidPeso molecular:767.86Ancriviroc
CAS:Ancriviroc (SCH-351125) is an orally bioavailable small molecule chemokine receptor CCR5 antagonist.Cost-effective and quality-assured.Fórmula:C28H37BrN4O3Pureza:99.76% - 99.82%Cor e Forma:SolidPeso molecular:557.533CCR2 antagonist 5
CAS:JNJ-41443532: oral hCCR2 antagonist, IC50=37 nM, anti-chemotaxis, treats inflammation & diabetes.Fórmula:C22H25F3N4O3SPureza:99.98%Cor e Forma:SolidPeso molecular:482.52BMS-817399
CAS:BMS-817399: oral CCR1 antagonist with binding and chemotaxis inhibition IC50s, potential for rheumatoid arthritis research.Fórmula:C23H36ClN3O4Pureza:99.7%Cor e Forma:SolidPeso molecular:454Ref: TM-T26861
1mg152,00€5mg319,00€10mg485,00€25mg770,00€50mg1.035,00€100mg1.395,00€1mL*10mM (DMSO)356,00€SB 328437
CAS:SB 328437 ((S)-methyl 2-(1-naphthamido)-3-(4-nitrophenyl)propanoate) is an effective and selective antagonist of CCR3 (IC50 = 4.5 nM).Fórmula:C21H18N2O5Pureza:99.54%Cor e Forma:SolidPeso molecular:378.38Ref: TM-T23321
1mg39,00€5mg82,00€10mg123,00€25mg250,00€50mg394,00€100mg618,00€200mg874,00€1mL*10mM (DMSO)69,00€BMS CCR2 22
CAS:BMS CCR2 22 is a potent and selective antagonist of CCR2 with calcium flux IC50 of 18 nM, chemotaxis IC50 of 1 nM, and binding IC50 of 5.1 nM.Fórmula:C28H34F3N5O4SPureza:99.65%Cor e Forma:SolidPeso molecular:593.66Ref: TM-T14688
1mg55,00€5mg110,00€10mg173,00€25mg349,00€50mg532,00€100mg718,00€200mg964,00€1mL*10mM (DMSO)147,00€GSK2239633A
CAS:GSK2239633A is an allosteric antagonist of CC-chemokine receptor 4 (CCR4) with a pIC50 of 7.96 for the binding of [125I]-TARC to human CCR4.Fórmula:C24H25ClN4O5S2Pureza:99.82%Cor e Forma:SolidPeso molecular:549.06Ref: TM-T11481
1mg35,00€5mg79,00€10mg118,00€25mg245,00€50mg355,00€100mg515,00€500mgA consultar1mL*10mM (DMSO)87,00€CCR1 antagonist 6
CAS:CCR1 antagonist 6 is a CCR1 antagonist (IC50: 3 nM).
Fórmula:C21H23ClN4O3SPureza:99.02% - 99.15%Cor e Forma:SolidPeso molecular:446.95Tanimilast
CAS:Tanimilast (CHF-6001) is a potent PDE4 inhibitor with IC50 of 0.026 nM, used topically for obstructive lung disease.Fórmula:C30H30Cl2F2N2O8SPureza:99.18%Cor e Forma:SolidPeso molecular:687.54CCR4 antagonist 4
CAS:CCR4 Antagonist 4 (Compound 22) is a potent and selective antagonist of the CC chemokine receptor-4 (CCR4), displaying an IC50 value of 0.02 μM. It also inhibits MDC-mediated chemotaxis and Ca2+ mobilization, with IC50 values of 0.007 μM and 0.003 μM, respectively. This compound is utilized in research on allergic inflammation [1].Fórmula:C24H27Cl2N7OCor e Forma:SolidPeso molecular:500.42MLN-3897
CAS:MLN-3897 is an oral CCR1 antagonist, Ki 2.3 nM, blocks 125I-MIP-1α binding, and inhibits Akt signaling in MM cells.Fórmula:C30H31ClN2O4Pureza:98.62%Cor e Forma:SolidPeso molecular:519.03
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