CCR
Os receptores de quimiocinas C-C (CCRs) são um grupo de GPCRs que respondem às quimiocinas, moléculas de sinalização que orientam a migração de células imunológicas para locais de inflamação ou infecção. Os CCRs desempenham papéis cruciais nas respostas imunológicas, inflamação e no desenvolvimento de várias doenças, incluindo distúrbios autoimunes e câncer. A modulação da atividade dos CCRs está sendo explorada como uma estratégia terapêutica para condições como artrite reumatoide, esclerose múltipla e infecção pelo HIV. Na CymitQuimica, oferecemos uma gama de moduladores de CCR de alta qualidade para apoiar sua pesquisa em imunologia, inflamação e desenvolvimento terapêutico.
Foram encontrados 141 produtos de "CCR"
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Vicriviroc
CAS:Vicriviroc, also known as MK4176 is a CCR5 antagonist.Fórmula:C28H38F3N5O2Cor e Forma:SolidPeso molecular:533.63Bindarit
CAS:Bindarit is a selective inhibitor of monocyte chemoattractant proteins MCP-1/CCL2, MCP-3/CCL7 and MCP-2/CCL8.Cost-effective and quality-assured.Fórmula:C19H20N2O3Pureza:98.35% - 98.55%Cor e Forma:SolidPeso molecular:324.37Ref: TM-T6413
1mg35,00€2mg50,00€5mg75,00€10mg110,00€25mg178,00€50mg314,00€100mg492,00€200mg710,00€1mL*10mM (DMSO)84,00€SB297006
CAS:SB297006 is an antagonist of C-C chemokine receptor 3, which normally is activated by eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1δ.Fórmula:C18H18N2O5Pureza:99.59%Cor e Forma:SolidPeso molecular:342.35BX471
CAS:BX471 (BX 471) is a potent, selective non-peptide CCR1 antagonist.Fórmula:C21H24ClFN4O3Pureza:98% - 99.98%Cor e Forma:SolidPeso molecular:434.89Ref: TM-T2375
1mg35,00€5mg86,00€10mg117,00€25mg200,00€50mg313,00€100mg489,00€200mg740,00€1mL*10mM (DMSO)95,00€R243
CAS:R243 is CCR8 signaling and chemotaxis inhibitor.Fórmula:C21H27NO4Pureza:99.03%Cor e Forma:SolidPeso molecular:357.44Ref: TM-T24700
1mg40,00€2mg52,00€5mg80,00€10mg117,00€25mg207,00€50mg333,00€100mg495,00€1mL*10mM (DMSO)90,00€TAK-779
CAS:TAK-779 (Takeda 779) is an antagonist of chemokine receptor 5 (CCR5), CCR2b, and CXC chemokine receptor 3 (CXCR3).Fórmula:C33H39ClN2O2Pureza:99.21%Cor e Forma:SolidPeso molecular:531.13INCB 3284
CAS:INCB 3284, a potent human CCR2 antagonist with an IC50 of 3.7 nM, is researchable for acute liver failure and inhibits MCP-1/hCCR2 binding.Fórmula:C26H31F3N4O4Pureza:97.81% - 99.42%Cor e Forma:SolidPeso molecular:520.54Carlumab
CAS:Carlumab is a high-affinity human monoclonal antibody that targets CCL2, suppressing the recruitment of monocytes/macrophages in the tumour microenvironment.Pureza:95%Cor e Forma:LiquidPeso molecular:144.87 kDaTivumecirnon
CAS:Tivumecirnon (FLX475) is a selective and oral CCR4 antagonist inhibits the infiltration and migration of Treg into the tumour microenvironment, antitumourFórmula:C24H27Cl2F3N6OPureza:99.88%Cor e Forma:SolidPeso molecular:543.41Ref: TM-T69834
1mg171,00€5mg418,00€10mg666,00€25mg1.334,00€50mg2.071,00€100mg2.879,00€1mL*10mM (DMSO)500,00€CCR8 antagonist 2
CAS:CCR8 antagonist 2 blocks CCR8 activity, mainly on Treg and Th2 cells, for treating related diseases. See WO2022000443A1, compound 220.Fórmula:C23H30ClN3O3SCor e Forma:SolidPeso molecular:464.02BMS-457
CAS:BMS-457 is a potent, CCR1-selective antagonist.Fórmula:C24H35ClN2O4Pureza:98%Cor e Forma:SolidPeso molecular:451AF-399/42018025
CAS:AF-399/42018025 is a small-molecule CCR4 antagonist applied to investigate chemokine-mediated immune cell trafficking and inflammatory disease mechanisms.Fórmula:C26H16ClN3O4S3Pureza:99.96%Cor e Forma:SolidPeso molecular:566.07CCR2 antagonist 3
CAS:CCR2 antagonist 3 (AZD-2927) is an antagonist of CCR2.Fórmula:C17H25FN2O2Pureza:99.87%Cor e Forma:SolidPeso molecular:308.39Ref: TM-T10712
1mg66,00€5mg147,00€10mg225,00€25mg398,00€50mg532,00€100mg745,00€200mg982,00€1mL*10mM (DMSO)161,00€RPT193
CAS:RPT193 is an oral CCR4 inhibitor reducing Th2 cell migration in atopic dermatitis, asthma, and allergies.Fórmula:C27H34Cl3N5O2Cor e Forma:SolidPeso molecular:566.95TAK-220
CAS:TAK-220: Oral CCR5 antagonist. IC50: 3.5 nM (RANTES), 1.4 nM (MIP-1α).Fórmula:C31H41ClN4O3Pureza:98%Cor e Forma:SolidPeso molecular:553.14BI-6901
CAS:BI-6901 is a CCR10 antagonist. In a mouse model of DNFB exposure hypersensitivity, BI 6901 displays its anti-inflammatory response in a dose-dependent manner.Fórmula:C23H27N5O3SPureza:99.83% - 99.94%Cor e Forma:SolidPeso molecular:453.56AZD-1678
CAS:AZD-1678 is a potent CCR4 receptor antagonist.Fórmula:C11H8Cl2FN3O3SCor e Forma:SolidPeso molecular:352.17CCX354
CAS:CCX354 (CCR1 antagonist 1) is a potent small molecule CCR1 antagonist with anti-inflammatory activity for the treatment of rheumatoid arthritis.Fórmula:C22H22ClN7O2Pureza:99.43% - 99.44%Cor e Forma:SolidPeso molecular:451.91C-021 dihydrochloride
CAS:C-021 dihydrochloride is a potent CCR4 antagonist. It potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM.Fórmula:C27H43Cl2N5O2Pureza:98.67%Cor e Forma:SolidPeso molecular:540.57CCR1 antagonist 7
CAS:CCR1 antagonist 7 (compound 16r) is an antagonist of chemokine receptor 1 (CCR1) with an IC 50 of 4 nM [1].Fórmula:C21H24ClN5O3SPureza:98%Cor e Forma:SolidPeso molecular:461.96
