CXCR
Os CXCRs são uma subclasse de GPCRs que se ligam a quimiocinas, pequenas proteínas sinalizadoras que guiam o movimento de células imunológicas em direção a locais de inflamação, infecção ou lesão. Os CXCRs desempenham papéis cruciais nas respostas imunológicas, metástase do câncer e doenças inflamatórias. Moduladores de CXCRs estão sendo investigados por seu potencial no tratamento de doenças autoimunes, câncer e condições inflamatórias crônicas. Na CymitQuimica, oferecemos uma gama de moduladores de CXCRs de alta qualidade para apoiar sua pesquisa em imunologia, oncologia e inflamação.
Foram encontrados 159 produtos para "CXCR".
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Delmetacin
CAS:Delmetacin: a non-steroidal anti-inflammatory drug with analgesic properties, inhibits CXCR1.Fórmula:C18H15NO3Pureza:99.91%Cor e Forma:SolidPeso molecular:293.32Quetmolimab
CAS:Quetmolimab is a humanized monoclonal antibody targeting chemokine ligand 1 (CX3CL1) that can be used to study rheumatoid arthritis.Pureza:SDS-PAGE:95% SEC-HPLC:97.59%Cor e Forma:Transparent LiquidPeso molecular:150 kDaLY2510924 acetate(1088715-84-7 free base)
Ly2510924 acetate is an potent and selective CXCR4 antagonist. It prevents the binding of SDF-1 to CXCR4 with an IC50 of 0.079 nM.Fórmula:C64H91N13O13Pureza:97.32%Cor e Forma:SolidPeso molecular:1250.49Ref: TM-T15805L
1mg150,00€5mg290,00€10mg434,00€1mL*10mM (DMSO)692,00€25mg710,00€50mg973,00€100mg1.341,00€Reparixin L-lysine salt
CAS:Reparixin L-lysine salt (Repertaxin L-lysine salt) is an allosteric chemokine receptor 1/2 (CXCR1/2) activation inhibitor.Fórmula:C20H35N3O5SPureza:99%Cor e Forma:SolidPeso molecular:429.57VUF11207 fumarate
CAS:VUF11207 fumarate is an agonist of CXCR7 and a high-potency ligand of CXCR7 (pKi: 8.1).Fórmula:C31H39FN2O8Pureza:97.98%Cor e Forma:SolidPeso molecular:586.65Ref: TM-T13324
1mg40,00€2mg52,00€5mg84,00€1mL*10mM (DMSO)92,00€10mg130,00€25mg259,00€50mg447,00€100mg645,00€200mg897,00€Eldelumab
CAS:Eldelumab (BMS-936557) is an anti-IP-10 IgG 1 monoclonal antibody.Eldelumab has anti-inflammatory activity and is used to study rheumatoid arthritis.Pureza:95%Cor e Forma:Transparent LiquidPeso molecular:146.64 kDaAMG 487
CAS:AMG 487: potent CXCR3 antagonist, blocks CXCL10/CXCL11 binding, IC50s: 8.0/8.2 nM.Fórmula:C32H28F3N5O4Pureza:99.82% - 99.89%Cor e Forma:SolidPeso molecular:603.59Ref: TM-T10297L
1mg52,00€5mg103,00€1mL*10mM (DMSO)138,00€10mg148,00€25mg235,00€50mg334,00€100mg528,00€200mg752,00€Motixafortide TFA(664334-36-5,Free)
Motixafortide TFA is a CXCR4 antagonist with ~1 nM IC50, promoting AML apoptosis by modulating miR-15a/16-1 and downregulating ERK and BCL-2.Fórmula:C99H145F4N33O21S2Pureza:>99.99%Cor e Forma:White SolidPeso molecular:2273.54Peptide R
CAS:Peptide R, a cyclic CXCR4 antagonist, remodels tumor stroma, aiding cancer research.Fórmula:C39H59N13O8S2Cor e Forma:SolidPeso molecular:902.1ITIC
CAS:"ITIC, a non-fullerene acceptor with high Tg of 180°C, shows excellent thermal stability and a low glass-crystal transition, plus unique crystallization."Fórmula:C94H82N4O2S4Pureza:98%Cor e Forma:SolidPeso molecular:1427.96CXCR4 antagonist 2
CAS:CXCR4 antagonist 2 is a CXCR4 antagonist with an IC 50 value of 47 nM.Fórmula:C25H36N6Cor e Forma:SolidPeso molecular:420.605CTCE-9908
CAS:CXCR4 blocker; triggers cell division failure in ovarian cancer, boosts taxol and docetaxel treatment effects, proven in mice.Fórmula:C86H147N27O23Pureza:98%Cor e Forma:SolidPeso molecular:1927.27ACKR3 agonist 1
ACKR3 agonist 1 (compound 27), exhibiting selective agonistic properties for ACKR3 (EC 50 =69 nM, E max =82%), demonstrates the capability to inhibit platelet aggregation and shows potential in mitigating platelet-mediated thrombosis. This compound is characterized by its metabolic stability and non-cytotoxic nature.Fórmula:C25H30N2OSCor e Forma:SolidPeso molecular:406.58PF-06835375
CAS:PF-06835375 is a humanized IgG1 antibody that selectively targets CXCR5 expressed on B cells, Tfh cells, and circulating Tfh-like cells (cTfh). It is applicable for research into systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA).Cor e Forma:LiquidCXCR4 antagonist 1
CAS:CXCR4 antagonist 1 is a potent inhibitor of the CXCR4 receptor, with notable anti-HIV activity.Fórmula:C27H43N7Cor e Forma:SolidPeso molecular:465.69TC14012
CAS:CXCR4 antagonist and ACKR3 (CXCR7) agonist (EC50 = 350 nM for CXCR7).Fórmula:C90H140N34O19S2Pureza:98%Cor e Forma:SolidPeso molecular:2066.43Vimnerixin
CAS:Vimnerixin (AZD4721) is an orally administered CXCR2 antagonist for inflammation studies.Fórmula:C19H25FN4O5S2Pureza:99.52%Cor e Forma:White SolidPeso molecular:472.55PDE4D inhibitor 1
PDE4-IN-1 is a PDE4 inhibitor characterized by high potency (IC50: 8.6 nM) and superior selectivity over other PDE subtypes. This compound inhibits the release of inflammatory cytokines and chemokines. Additionally, PDE4-IN-1 significantly restores the damaged cAMP-CREB signaling pathway, inhibits proliferation, and promotes differentiation to reverse psoriasis formation.Cor e Forma:Odour SolidITIC-4F
CAS:ITIC-4F: a postfullerene IDTT electron acceptor for high-efficiency PSCs, relevant in binary, ternary, and tandem setups.Fórmula:C94H78F4N4O2S4Pureza:98%Cor e Forma:SolidPeso molecular:1499.92Bam 12P
CAS:Bam 12P is a Pro-Met-enkephalin precursor that is isolated from the bovine adrenal medulla.Fórmula:C62H97N21O16SPureza:98%Cor e Forma:SolidPeso molecular:1424.64
