NOD
As proteínas NOD são receptores intracelulares que reconhecem componentes microbianos e desempenham um papel crucial na resposta imune inata, ativando vias de sinalização inflamatória, incluindo NF-κB. Os receptores NOD estão envolvidos na detecção de infecções bacterianas e estão associados à patogênese de doenças inflamatórias intestinais, distúrbios autoimunes e inflamação crônica. Na CymitQuimica, oferecemos uma variedade de moduladores da via NOD de alta qualidade para apoiar sua pesquisa em imunidade inata, inflamação e saúde gastrointestinal.
Foram encontrados 18 produtos de "NOD"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
BAL-0028
CAS:<p>BAL-0028 is a potent inhibitor of NLRP3 activation (IC50: 25 nM) with anti-inflammatory activity for cancer research.</p>Fórmula:C24H22FN3O2Pureza:99.16%Cor e Forma:SoildPeso molecular:403.45BMS986299
CAS:BMS986299 is a modulator of NLRP3 with an EC50 of 1.28 μM and can be used in studies about NLRP3 signaling and the treatment of associated diseases.Fórmula:C18H19N7OPureza:99.93% - 99.93%Cor e Forma:SolidPeso molecular:349.39NT-0249
CAS:NT-0249 is an inflammatory vesicle NLRP3 inhibitor with anti-inflammatory activity that reverses high-fat diet-induced obesity.Fórmula:C22H28N5NaO4SPureza:98.11%Cor e Forma:SoildPeso molecular:481.54NP3-146
CAS:<p>NP3-146 (NLRP3-IN-5) is an inflammasome NLRP3 inhibitor with potential anti-inflammatory activity for the study of autoimmune diseases.</p>Fórmula:C20H27ClN2O5SPureza:99.21%Cor e Forma:SolidPeso molecular:442.96MCC950
CAS:MCC950 (CP-456773) is a NLRP3 inflammasome inhibitor (IC50=7.5-8.1 nM). MCC950 can be used to treat inflammatory diseases. High-Quality, Low-Cost!Fórmula:C20H24N2O5SPureza:97% - 98%Cor e Forma:SolidPeso molecular:404.48Diisononyl phthalate
CAS:Diisononyl phthalate (DINP), a phthalate, a plasticizer, activates the ACE/AT1R axis and inhibits NO production, inducing elevated blood pressure in mice.Fórmula:C26H42O4Pureza:99.97%Cor e Forma:Colorless Liquid In Water (Uscg 1999)Peso molecular:418.61LL-37 GKE acetate
LL-37 GKE acetate, a peptide and active structural domain of LL-37, inhibits lps-induced vascular nitric oxide production,less toxic,antimicrobial，sepsis.Fórmula:C121H206N38O30Pureza:99.88%Cor e Forma:SolidPeso molecular:2673.17Muramyl dipeptide
CAS:MDP is a synthetic peptide promoting bone formation by modulating osteoclasts, osteoblasts, and Runx2 expression via MAPK pathways.Fórmula:C19H32N4O11Pureza:99.34%Cor e Forma:SolidPeso molecular:492.48Nodinitib-1
CAS:Nodinitib-1 (CID-1088438) is a potent and selective NOD1 inhibitor with an IC50 of 0.56 μM.Fórmula:C14H13N3O2SPureza:99.97% - >99.99%Cor e Forma:SolidPeso molecular:287.34NLRP3-IN-11
CAS:NLRP3-IN-11 is an NLRP3 protein inhibitor with potential anti-inflammatory activity.NLRP3-IN-11 can be used in the study of atherosclerosis and parkinsonism.Fórmula:C17H17ClN4O2Pureza:>99.99%Cor e Forma:SolidPeso molecular:344.8AZD4144
CAS:AZD4144 is a potent and selective NLRP3 inhibitor (IC50 = 54 nM) that reducs IL-1β and IL-18 production for immune disorders.Fórmula:C18H16F3N3O3Pureza:99.02%Cor e Forma:SoildPeso molecular:379.33Emlenoflast sodium
CAS:Emlenoflast sodium (MCC7840 sodium), a sulfonylurea, is a selective NLRP3 inflammasome inhibitor with an IC50 value of less than 100 nM for NLRP3 inflammasome,Fórmula:C19H24N4NaO3SCor e Forma:SolidPeso molecular:411.47NLRP3-IN-13
CAS:<p>NLRP3-IN-13 is an NLRP3 inhibitor that inhibits NLRP3-associated inflammation.NLRP3-IN-13 can be used in the study of neurological disorders and inflammation.</p>Fórmula:C19H15N3O3SPureza:99.16%Cor e Forma:SolidPeso molecular:365.41JC124
CAS:JC124 is an inhibitor of NLRP3 Inflammasome and exhibits neuroprotective and anti-inflammatory activities.Fórmula:C17H19ClN2O4SPureza:99.64%Cor e Forma:SolidPeso molecular:382.86NLRP3-IN-10
CAS:NLRP3-IN-10 (ZVN26391) is a strong NLRP3 inhibitor, IC50 251.1 nM, that reduces IL-1β and ASC speck, hindering inflammasome activation.Fórmula:C17H14BrFO3Pureza:99.06%Cor e Forma:SolidPeso molecular:365.19NLRP3-IN-9
CAS:NLRP3-IN-9 (INF-4E) irreversibly inhibits NLRP3 ATPase, caspase-1, and prevents pyroptosis in THP-1 cells.Fórmula:C12H13ClO3Pureza:99.64%Cor e Forma:SolidPeso molecular:240.68Usnoflast
CAS:Usnoflast (ZYIL1) is an NLRP3 inhibitor, inhibiting NLRP3 inflammasome activation, used in neurological disease research.Fórmula:C21H29N3O3SPureza:98.79%Cor e Forma:SolidPeso molecular:403.54NOD1/2 antagonist-1
CAS:<p>NOD1/2 antagonist-1 inhibits NOD1 (IC50 1.13 μM) and NOD2 (IC50 0.77 μM), enhances paclitaxel antitumor efficacy and is used to study innate immune signaling.</p>Fórmula:C32H28ClF5N4O4Pureza:99.69%Cor e Forma:SolidPeso molecular:663.03
