NOD
As proteínas NOD são receptores intracelulares que reconhecem componentes microbianos e desempenham um papel crucial na resposta imune inata, ativando vias de sinalização inflamatória, incluindo NF-κB. Os receptores NOD estão envolvidos na detecção de infecções bacterianas e estão associados à patogênese de doenças inflamatórias intestinais, distúrbios autoimunes e inflamação crônica. Na CymitQuimica, oferecemos uma variedade de moduladores da via NOD de alta qualidade para apoiar sua pesquisa em imunidade inata, inflamação e saúde gastrointestinal.
Foram encontrados 17 produtos de "NOD"
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BAL-0028
CAS:<p>BAL-0028 is a potent inhibitor of NLRP3 activation (IC50: 25 nM) with anti-inflammatory activity for cancer research.</p>Fórmula:C24H22FN3O2Pureza:99.16%Cor e Forma:SoildPeso molecular:403.45NP3-146
CAS:<p>NP3-146 (NLRP3-IN-5) is an inflammasome NLRP3 inhibitor with potential anti-inflammatory activity for the study of autoimmune diseases.</p>Fórmula:C20H27ClN2O5SPureza:99.21%Cor e Forma:SolidPeso molecular:442.96NT-0249
CAS:<p>NT-0249 is an inflammatory vesicle NLRP3 inhibitor with anti-inflammatory activity that reverses high-fat diet-induced obesity.</p>Fórmula:C22H28N5NaO4SPureza:98.11%Cor e Forma:SoildPeso molecular:481.54MCC950
CAS:<p>MCC950 (CP-456773) is a NLRP3 inflammasome inhibitor (IC50=7.5-8.1 nM). MCC950 can be used to treat inflammatory diseases. High-Quality, Low-Cost!</p>Fórmula:C20H24N2O5SPureza:97% - 98%Cor e Forma:SolidPeso molecular:404.48BMS986299
CAS:<p>BMS986299 is a modulator of NLRP3 with an EC50 of 1.28 μM and can be used in studies about NLRP3 signaling and the treatment of associated diseases.</p>Fórmula:C18H19N7OPureza:99.93% - 99.93%Cor e Forma:SolidPeso molecular:349.39LL-37 GKE acetate
<p>LL-37 GKE acetate, a peptide and active structural domain of LL-37, inhibits lps-induced vascular nitric oxide production,less toxic,antimicrobial，sepsis.</p>Fórmula:C121H206N38O30Pureza:99.88%Cor e Forma:SolidPeso molecular:2673.17Muramyl dipeptide
CAS:<p>MDP is a synthetic peptide promoting bone formation by modulating osteoclasts, osteoblasts, and Runx2 expression via MAPK pathways.</p>Fórmula:C19H32N4O11Pureza:99.34%Cor e Forma:SolidPeso molecular:492.48NLRP3-IN-11
CAS:<p>NLRP3-IN-11 is an NLRP3 protein inhibitor with potential anti-inflammatory activity.NLRP3-IN-11 can be used in the study of atherosclerosis and parkinsonism.</p>Fórmula:C17H17ClN4O2Pureza:>99.99%Cor e Forma:SolidPeso molecular:344.8AZD4144
CAS:<p>AZD4144 is a potent and selective NLRP3 inhibitor (IC50 = 54 nM) that reducs IL-1β and IL-18 production for immune disorders.</p>Fórmula:C18H16F3N3O3Pureza:99.02%Cor e Forma:SoildPeso molecular:379.33NLRP3-IN-13
CAS:<p>NLRP3-IN-13 is an NLRP3 inhibitor that inhibits NLRP3-associated inflammation.NLRP3-IN-13 can be used in the study of neurological disorders and inflammation.</p>Fórmula:C19H15N3O3SPureza:99.16%Cor e Forma:SolidPeso molecular:365.41Emlenoflast sodium
CAS:<p>Emlenoflast sodium (MCC7840 sodium), a sulfonylurea, is a selective NLRP3 inflammasome inhibitor with an IC50 value of less than 100 nM for NLRP3 inflammasome,</p>Fórmula:C19H24N4NaO3SCor e Forma:SolidPeso molecular:411.47NLRP3-IN-10
CAS:<p>NLRP3-IN-10 (ZVN26391) is a strong NLRP3 inhibitor, IC50 251.1 nM, that reduces IL-1β and ASC speck, hindering inflammasome activation.</p>Fórmula:C17H14BrFO3Pureza:99.06%Cor e Forma:SolidPeso molecular:365.19JC124
CAS:<p>JC124 is an inhibitor of NLRP3 Inflammasome and exhibits neuroprotective and anti-inflammatory activities.</p>Fórmula:C17H19ClN2O4SPureza:99.64%Cor e Forma:SolidPeso molecular:382.86NLRP3-IN-9
CAS:<p>NLRP3-IN-9 (INF-4E) irreversibly inhibits NLRP3 ATPase, caspase-1, and prevents pyroptosis in THP-1 cells.</p>Fórmula:C12H13ClO3Pureza:99.64%Cor e Forma:SolidPeso molecular:240.68ADS032
CAS:<p>ADS032 (BT-032) is an NLRP1 and NLRP3 inhibitor with anti-inflammatory activity for the study of respiratory inflammation or infection.</p>Fórmula:C22H29NO4SPureza:98.37%Cor e Forma:SolidPeso molecular:403.54Usnoflast
CAS:<p>Usnoflast (ZYIL1) is an NLRP3 inhibitor, inhibiting NLRP3 inflammasome activation, used in neurological disease research.</p>Fórmula:C21H29N3O3SPureza:98.79%Cor e Forma:SolidPeso molecular:403.54NOD1/2 antagonist-1
CAS:<p>NOD1/2 antagonist-1 inhibits NOD1 (IC50 1.13 μM) and NOD2 (IC50 0.77 μM), enhances paclitaxel antitumor efficacy and is used to study innate immune signaling.</p>Fórmula:C32H28ClF5N4O4Pureza:99.69%Cor e Forma:SolidPeso molecular:663.03
