NOD
As proteínas NOD são receptores intracelulares que reconhecem componentes microbianos e desempenham um papel crucial na resposta imune inata, ativando vias de sinalização inflamatória, incluindo NF-κB. Os receptores NOD estão envolvidos na detecção de infecções bacterianas e estão associados à patogênese de doenças inflamatórias intestinais, distúrbios autoimunes e inflamação crônica. Na CymitQuimica, oferecemos uma variedade de moduladores da via NOD de alta qualidade para apoiar sua pesquisa em imunidade inata, inflamação e saúde gastrointestinal.
Foram encontrados 28 produtos para "NOD".
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Dapansutrile
CAS:Dapansutrile is a potent, selective and orally active NLRP3 inflammasome inhibitor, with Anti-inflammatory and analgesic activity.Fórmula:C4H7NO2SPureza:≥98% - ≥98%Cor e Forma:SolidPeso molecular:133.169Diisononyl phthalate
CAS:Produto ControladoDiisononyl phthalate (DINP), a phthalate, a plasticizer, activates the ACE/AT1R axis and inhibits NO production, inducing elevated blood pressure in mice.Fórmula:C26H42O4Pureza:99.97%Cor e Forma:Colorless Liquid In Water (Uscg 1999)Peso molecular:418.6093NP3-146
CAS:NP3-146 (NLRP3-IN-5) is an inflammasome NLRP3 inhibitor with potential anti-inflammatory activity for the study of autoimmune diseases.Fórmula:C20H27ClN2O5SPureza:98.97%Cor e Forma:White SolidPeso molecular:442.96MCC950
CAS:MCC950 (CP-456773) is a NLRP3 inflammasome inhibitor (IC50=7.5-8.1 nM). MCC950 can be used to treat inflammatory diseases. High-Quality, Low-Cost!Fórmula:C20H24N2O5SPureza:97% - 99.89%Cor e Forma:White SolidPeso molecular:404.48NT-0249
CAS:NT-0249 is an inflammatory vesicle NLRP3 inhibitor with anti-inflammatory activity that reverses high-fat diet-induced obesity.Fórmula:C22H28N5NaO4SPureza:97.26%Cor e Forma:Yellow SolidPeso molecular:481.54BMS986299
CAS:BMS986299 is a modulator of NLRP3 with an EC50 of 1.28 μM and can be used in studies about NLRP3 signaling and the treatment of associated diseases.Fórmula:C18H19N7OPureza:99.93% - 99.93%Cor e Forma:White SolidPeso molecular:349.39Mifamurtide
CAS:Mifamurtide (MTP-PE) is a NOD2 ligand used in macrophage activation and innate immune signaling research.Fórmula:C59H109N6O19PPureza:98%Cor e Forma:SolidPeso molecular:1237.50LL-37 GKE acetate
LL-37 GKE acetate, a peptide and active structural domain of LL-37, inhibits lps-induced vascular nitric oxide production,less toxic,antimicrobial，sepsis.Fórmula:C121H206N38O30Pureza:99.88%Cor e Forma:SolidPeso molecular:2673.17Oxidized ATP trisodium salt
CAS:Oxidized ATP trisodium salt is an irreversible P2X7R inhibitor suppressing NLRP3 inflammasome activation.Fórmula:C10H11N5Na3O13P3Pureza:98%Cor e Forma:SolidPeso molecular:571.11Muramyl dipeptide
CAS:MDP is a synthetic peptide promoting bone formation by modulating osteoclasts, osteoblasts, and Runx2 expression via MAPK pathways.Fórmula:C19H32N4O11Pureza:98% - 99.34%Cor e Forma:White SolidPeso molecular:492.4776NOD-IN-1
CAS:NOD-IN-1 (Compound 4) is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptors.Fórmula:C18H17NO4SPureza:99.92% - 99.93%Cor e Forma:White SolidPeso molecular:343.397Nodinitib-1
CAS:Nodinitib-1 (CID-1088438) is a potent and selective NOD1 inhibitor with an IC50 of 0.56 μM.Fórmula:C14H13N3O2SPureza:99.71% - >99.99%Cor e Forma:SolidPeso molecular:287.34NLRP3-IN-2
CAS:NLRP3-IN-2 (5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide), an intermediate capable of synthesizing glibenclamide.Fórmula:C16H17ClN2O4SPureza:98.98%Cor e Forma:SolidPeso molecular:368.835INF39
CAS:INF39 is a noncytotoxic and irreversible NLRP3 inhibitor.Fórmula:C12H13ClO2Pureza:99.5% - 99.78%Cor e Forma:SolidPeso molecular:224.683CY-09
CAS:CY-09 is an NLRP3 inhibitor.Fórmula:C19H12F3NO3S2Pureza:99.75% - >99.99%Cor e Forma:SolidPeso molecular:423.43MCC950 sodium
CAS:MCC950 sodium (CP-456773 sodium) is a potent and selective inhibitor of the inflammatory vesicle NLRP3 (IC50=7.5 nM in BMDMs; IC50=8.1 nM in HMDMs).Fórmula:C20H23N2NaO5SPureza:95.49% - 99.80%Cor e Forma:SolidPeso molecular:426.46NLRP3-IN-11
CAS:NLRP3-IN-11 is an NLRP3 protein inhibitor with potential anti-inflammatory activity.NLRP3-IN-11 can be used in the study of atherosclerosis and parkinsonism.Fórmula:C17H17ClN4O2Pureza:99.99%Cor e Forma:Yellow SolidPeso molecular:344.8AZD4144
CAS:AZD4144 is a potent and selective NLRP3 inhibitor (IC50 = 54 nM) that reducs IL-1β and IL-18 production for immune disorders.Fórmula:C18H16F3N3O3Pureza:99.02%Cor e Forma:Yellow SolidPeso molecular:379.33Emlenoflast sodium
CAS:Emlenoflast sodium (MCC7840 sodium), a sulfonylurea, is a selective NLRP3 inflammasome inhibitor with an IC50 value of less than 100 nM for NLRP3 inflammasome,Fórmula:C19H24N4NaO3SCor e Forma:SolidPeso molecular:411.47NOD2 antagonist 1
CAS:NOD2 antagonist 1 is a selective NOD2 antagonist (IC50=5.23 μM) that suppresses MDP-induced cytokine secretion (IL-8, IL-6, TNF-α) in THP-1 and PBMCs.Fórmula:C26H26N4O3SPureza:98.83%Cor e Forma:White SolidPeso molecular:474.57
